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NCT ID: NCT05564442 Recruiting - Anesthesia, Local Clinical Trials

Compare the Efficacy of Various Pain Alleviating Methods in Reducing Pain in Children During Intraoral Local Anaesthetic Injections

Start date: June 5, 2022
Phase: N/A
Study type: Interventional

The aim of study is to compare the efficacy of various pain alleviating methods by application of Emla gel, TENS, and topical cooling of injection sites compared with 20% benzocaine gel in reducing pain in children requiring anesthesia during routine dental procedures.

NCT ID: NCT05563636 Recruiting - Clinical trials for Failed Back Surgery Syndrome

High Voltage VS Standard Voltage Radiofrequency in a Patient With Failed Back Surgery Syndrome

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

Postoperative lumbar spine pain syndrome (FBSS) refers to patients who have undergone surgery for lumbar spine disease one or more times and still have intractable lumbosacral pain after surgery, with or without lower limb sensory and motor dysfunction. Pain is the main reason for reducing patients' quality of life. Hussain and Erdek believe that despite up to 3 months of postoperative intervention, pain may still exist. Since persistent pain seriously affects patients' daily life and work, optimizing the FBSS treatment plan and improving the quality of life of FBSS patients cannot be ignored. At present, the treatment methods for neuropathic pain radiated to the lower extremity after lumbar spine surgery mainly include oral drug therapy, nerve block, pulsed radio frequency (PRF) and spinal cord electrical stimulation, and other minimally invasive interventional methods. Still, there is no domestic or foreign treatment method is reported in the literature to be effective.

NCT ID: NCT05561881 Recruiting - Clinical trials for Genicular Nerve Block

Genicular Nerve Block Versus IPACK Block for Knee Arthroscopic Surgery

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

Postoperative pain management after knee arthroscopic surgery continues to evolve with better treatment strategies being formulated to improve patient satisfaction, and clinical outcomes and reduce opioid use in the immediate postoperative period. appropriate perioperative pain management has been shown to result in faster recovery and rehabilitation leading to better functional outcomes in patients undergoing knee arthroscopic surgery. this has necessitated the development of multimodal analgesics. peripheral nerve blockade has been reported to deliver optimal postoperative pain relief and is increasingly preferred in patients undergoing arthroscopic procedures and various different techniques such as sciatic nerve block, femoral nerve block, and genicular block have been described.

NCT ID: NCT05561569 Recruiting - Retinal Detachment Clinical Trials

Air Versus Gas Tamponade in Primary Retinal Detachment

Start date: September 26, 2022
Phase: N/A
Study type: Interventional

Management of primary retinal detachment due to upper retinal break is one of controversial situation that may face ophthalmologists in vitreoretinal subspecialty.

NCT ID: NCT05561062 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Atorvastatin in Patients With Ulcerative Colitis

Start date: December 1, 2022
Phase: Phase 2
Study type: Interventional

Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa; however, the exact underlying mechanisms of UC remain poorly understood. Statins exert numerous pleiotropic effects including anti-inflammatory, antioxidant properties, endothelial function improvement, and immunomodulation independent of their basic lipid-lowering property.

NCT ID: NCT05559723 Recruiting - Clinical trials for Lumbar Disc Herniation

Effect of Electromagnetic Field in Lumbar Disc Prolapse Patients

Start date: November 25, 2022
Phase: N/A
Study type: Interventional

to investigate the effect of electromagnetic field therapy on sciatica and postural control in lumbar disc prolapse patients BACKGROUND: lumbar disc prolapse is a clinical condition resulting from compression of lumbar nerve roots resulting in decreased postural control and alleviating sciatic pain Pulsed electromagnetic field (PEMF) therapy is an easy, non-invasive, safe, and relatively new treatment method that is used with growing interest in physical and rehabilitation medicine. Historically, the benefits from magnetotherapy have been reported for patients with musculoskeletal and neurological disorders

NCT ID: NCT05559632 Recruiting - Clinical trials for Completely Edentulous Maxilla

Peri-Implant Marginal Bone Loss And Implant Stability In Maxillary Implant Overdenture When Using Osseodensification Versus Conventional Drills: A Randomized Clinical Trial

Start date: November 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Is to compare between the conventional drills versus osseodensification drills for implant stability and peri-implant marginal bone loss in maxillary implant overdenture.

NCT ID: NCT05558761 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Pentoxifylline as Adjunctive Therapy in Patients With Ulcerative Colitis

Start date: October 10, 2022
Phase: Phase 2
Study type: Interventional

The exact underlying mechanisms of ulcerative colitis (UC), an idiopathic, chronic inflammatory disease marked by diffused inflammation of the colon and rectum mucosa, are still unknown. Due to genetic, immune, and environmental factors, UC is highly dependent on cellular immune reactions and exaggerated inflammatory responses. The release of several cytokines, kinins, leukotrienes, platelet-activating factor (PAF), and reactive oxygen species is connected to immunological activity (ROS). Additionally, many of the cytokines will start an acute phase response, making the inflammation worse.

NCT ID: NCT05557734 Recruiting - Motor Activity Clinical Trials

Compartive Study Between Caudal and Perianal Block During Anal Sphincter Sparing Procedures Under General Anesthesia

Start date: October 14, 2023
Phase: N/A
Study type: Interventional

Anal fistula is an abnormal tract communicating an external opening in the perianal skin with an internal opening in the anal canal. Anal fistula is treated by fistulotomy . sphincter sparing procedures are usually done under general anesthesia omitting neuromuscular blocking agents in order to preserve sphincter tone intraoperatively. The aim of this study is to evaluate the effect of caudal block analgesia versus perianal block analgesia combined with general anesthesia on the postoperative analgesic profile and the tone of external anal sphincter in sphincter sparing surgery.

NCT ID: NCT05556759 Recruiting - Hip Arthropathy Clinical Trials

Anterior Iliopsoas Muscle Space Block Versus Supra-iliac Anterior Quadratus Lumborum Block in Total Hip Arthroplasty

Start date: September 30, 2022
Phase: N/A
Study type: Interventional

Approximately 1.66 million hip fractures happen in a year worldwide. About 95% of these fractures happen in individuals older than 60 years. Surgical treatment involving THA is considered the best option for patients with hip fractures and those with degenerative changes in the hip joint, especially in the elderly, however, it is associated with moderate to severe postoperative pain. Pain is one of the main factors limiting ambulation, increasing the risk of thromboembolism by immobility, and causing metabolic changes that affect other systems. Therefore, individualized pain management with the use of appropriate analgesia techniques is of paramount importance. Moreover, early intervention of rehabilitation aiming at a better postoperative recovery may reduce the length of hospital stay and return to daily. Effective pain management is one of the crucial components of enhanced recovery after surgery (ERAS). Numerous regional anesthetic techniques have been used to provide analgesia following THA, including intrathecal morphine, epidural analgesia, fascia iliaca block, lumber plexus block, sacral plexus block, and local infiltration analgesia, however, each of these techniques has specific limitations that prevent them from being the analgesic technique of choice for THA. Up to investigators' knowledge, there is no study done to compare the supra-iliac approach to the anterior QL block versus the Anterior iliopsoas muscle space block as pre-emptive analgesia in patients undergoing THA under general anesthesia