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NCT ID: NCT05584033 Recruiting - Apraxia of Speech Clinical Trials

Searching of Apraxia of Speech in Children With Specific Language Impairment

Start date: October 2022
Phase:
Study type: Observational

Searching of Apraxia of Speech in Children with Specific Language Impairment

NCT ID: NCT05583370 Recruiting - Aflatoxin Poisoning Clinical Trials

The Effect of Aflatoxin Metabolites Concentration in Follicular Fluid on Laboratory and Clinical Outcomes in ICSI

Start date: November 1, 2023
Phase:
Study type: Observational

Mycotoxins are secondary toxic metabolites produced by Aspergillus, Penicillium, and Fusarium species of fungi, when they infect and proliferate on various agricultural commodities either in the field and/or during storage. The well-known detrimental health effects of mycotoxins in humans include liver cancer, Balkan endemic nephropathy, child growth impairment, immune suppression, neural tube defects and death in acute exposure. However, growing evidence also suggests that mycotoxins may negatively influence human fertility.

NCT ID: NCT05583253 Recruiting - Refractive Errors Clinical Trials

Visual Outcome of Vitrectomy After Refractive Surgery

Start date: October 13, 2022
Phase: N/A
Study type: Interventional

Results of retinal detachment surgery may be affected in cases with history of previous intraocular surgery.

NCT ID: NCT05581537 Recruiting - Stroke Clinical Trials

Effect of Adding Systematic Desensitization to Goal Directed Paradigm on Risk of Falling in Patients With Stroke

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Stroke is the leading cause of disability in the elderly . The most common manifestations of stroke are deficits in motor control that involve abnormal synergistic organization of movements, muscle weakness, sensory deficits, and loss of range of motion. Poor posture, which is one of its main symptoms, affects falls or injured falls. Fear of falling is a psychological condition associated with balance disorders and fall risks after a stroke.

NCT ID: NCT05579613 Recruiting - Clinical trials for Forward Head Posture

Effect of Interactive Virtual Reality Device on Cervical Proprioception and Range of Motion in Forward Head Posture

Start date: June 20, 2022
Phase: N/A
Study type: Interventional

Forward head posture (FHP) is one of the most common postural deformities, which affects 66% of the patient population and this study will be designed to investigate the effect of interactive virtual reality device on cervical proprioception and range of motion in symptomatic forward head posture.

NCT ID: NCT05578638 Recruiting - Pressure Injury Clinical Trials

Comparing Aloe Vera Gel and Rosemary Oil in Pressure Injury Prevention

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Most patients admitted to the orthopedic ward are at risk of developing pressure ulcers. Today, the tendency to use medicinal herbs in pressure ulcer treatment has increased due to the variety of effective compounds and their fewer side effects.

NCT ID: NCT05576818 Recruiting - Parkinson Disease Clinical Trials

Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease

Start date: June 30, 2022
Phase: Phase 3
Study type: Interventional

This study aims to investigate the possible efficacy and safety of synbiotic preparation of Lactobacillus acidophilus probiotic with prebiotic fibers as an adjuvant therapy in the treatment of Parkinson's disease

NCT ID: NCT05576519 Recruiting - Ovarian Carcinoma Clinical Trials

Immunohistochemical Expression of Epithelial Cell Adhesion Molecule (EpCAM) in Epithelial Ovarian Carcinoma

Start date: June 1, 2017
Phase:
Study type: Observational

Cancer stem cells (CSCs) can undergo self-renewal and differentiation. EpCAM is a 40-kDa type I transmembrane glycoprotein composed of a large extracellular domain, one transmembrane region, and a small intracellular domain of 26 amino acids. Recent insights revealed that it is involved in promoting cancer cell proliferation, migration, and invasiveness. It is used as a diagnostic and prognostic marker. EpCAM has also recently been identified as a marker for CSCs.

NCT ID: NCT05575505 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Phosphodiesterase Inhibitors, Pentoxifylline, as Adjunctive Therapy in Patients With Ulcerative Colitis.

Start date: February 2, 2023
Phase: Phase 2
Study type: Interventional

Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa; however, the exact underlying mechanisms of UC remain poorly understood. Also, it is associated with high risk of colon cancer, so there is a continuous need for introducing new therapies that decrease progression, and hence better outcomes

NCT ID: NCT05574387 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Metformin as Added on Therapy in Patients With Ulcerative Colitis

Start date: January 20, 2023
Phase: Phase 2
Study type: Interventional

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is marked by increased intestinal motility and bloody diarrhea. The clinical value of existing therapeutic strategies of UC, including glucocorticoids, anti-tumor necrosis factor α (TNF-α), mesalamine, and thiopurines is still limited. Therefore, the discovery of new therapeutic approaches is essential to improve the effectiveness of the treatment.Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a conserved fuel-sensing enzyme that plays an important role in the regulation of cellular metabolism where it increases glucose and fatty acids uptake and activates the oxidation process to improve the cellular energy utilization