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NCT ID: NCT05660616 Recruiting - Clinical trials for Malignant Pleural Mesothelioma

Switch-Maintenance Gemcitabine After First-Line Chemotherapy In Patients With Malignant Pleural Mesothelioma

Start date: April 1, 2023
Phase: Phase 2
Study type: Interventional

Mesothelioma is an aggressive form of cancer. Treatments are available, but for many people, a cure isn't possible. This thesis is to assess the efficacy and safety of switch-maintenance Gemcitabine in Mesothelioma patients after first line chemotherapy (Pemetrexed-Platinum)

NCT ID: NCT05660603 Recruiting - Hip Fractures Clinical Trials

Circum-Psoas Blocks Versus Combined Lumbar and Sacral Plexus Blocks in Hip Fracture Surgery

Start date: December 20, 2022
Phase: N/A
Study type: Interventional

Hip fracture (HF) is one of the major worldwide problems that constitute a significant mortality rate, ranging from 14- 36% in the first year after injury, and is associated with profound temporary and sometimes permanent impairment of independence and quality of life in the geriatric population. Surgical treatment is considered the best option for patients with hip fractures,s especially in the elderly, however, it is associated with moderate to severe postoperative pain. Pain is one of the main factors limiting ambulation, increasing the risk of thromboembolism by immobility and causing metabolic changes that affect other systems. Therefore, individualized pain management with the use of appropriate analgesic techniques is of paramount importance. Moreover, early intervention of rehabilitation aiming at a better postoperative recovery may reduce the length of hospital stay and return to daily. Effective pain management is one of the crucial components in enhanced recovery after surgery (ERAS). • Numerous regional anesthetic techniques have been used to provide analgesia following hip fracture surgery, including intrathecal morphine, epidural analgesia, fascia iliaca block, lumber plexus block, and sacral plexus block, however, each of these techniques has specific limitations that prevent them from being the analgesic technique of choice for hip fracture surgery. To our knowledge, there is no study done to compare circum-psoas block versus the combined lumbar and sacral plexus blocks as pre-emptive analgesia in patients undergoing hip fracture surgery under general anesthesia.

NCT ID: NCT05658991 Recruiting - Obesity Clinical Trials

Electrophysiological Changes With Diet.

Start date: December 11, 2022
Phase: N/A
Study type: Interventional

Dietary habits may affect our body by certain mechanisms, visual sense is one of the most vital human senses that needs special attention in our daily habits.

NCT ID: NCT05658900 Recruiting - Jaw Cysts Clinical Trials

Volumetric Analysis of Bone Following Jaw Cysts Enucleation With and Without Alb-PRF

Start date: May 19, 2022
Phase: N/A
Study type: Interventional

Cyst is the main cause for longstanding swelling in the mandible or the maxilla, its enlargement usually results in resorption and weakening of bone. Thus the treatment of the cysts is essential to preserve the bone and the adjacent vital structures. Healing of the bone defect and its surrounding soft tissues is a critical issue that needs concerns. Although the Platelet rich fibrin has promising effects in wound healing, it can resorb during 10-14 days. Thus a new autologous platelet concentrate is introduced by Kawasi et al that can remain stable for 4-6 months called albumin PRF.

NCT ID: NCT05658848 Recruiting - Fertility Issues Clinical Trials

Effect of Collaborative Infertility Counseling on Coping Strategies and Marital Satisfaction

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

Effect of collaborative infertility counseling on coping strategies and marital satisfaction among women undergoing in vitro fertilization: a randomized control trial

NCT ID: NCT05657132 Recruiting - Infection Primary Clinical Trials

Antibacterial Effect of New Herbal Paste Used as an Intracanal Medication

Start date: August 19, 2021
Phase: Phase 3
Study type: Interventional

studying the antibacterial effect of Cosuts paste as an intracanal medication against Enterococcus faecalis that present in necrotic primary teeth

NCT ID: NCT05657028 Recruiting - Anesthesia Clinical Trials

Dexmedetomidine Versus Lidocaine in Attenuating Airway Reflexes During Recovery of Thyroidectomy Patients

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

It is widely believed that most of the patients experience a cough upon emergence from general anesthesia, due to many causes including the presence of an endotracheal tube, uncleared secretions and anesthetic gas. Cough during tracheal extubation may lead to several complications, such as hypertension, tachycardia and postoperative bleeding. In this study the investigators are going to compare the effectiveness of intravenous Dexmedetomidine and intravenous lidocaine in attenuating the air way reflexes and coughing during recovery of thyroidectomy patients.

NCT ID: NCT05655923 Recruiting - Periodontitis Clinical Trials

Clinical and Biochemical Assessment of Ozonated Olive Oil Mixed Bone Substitute in Treating Intra Bony Periodontal Defect

Start date: July 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

The goal of this study is to investigate the effect of ozonated olive oil in treating intra bony defect by means of clinical and radiographic parameters, and gingival cervicular fluid BMP2 level.

NCT ID: NCT05655806 Recruiting - Anesthesia Clinical Trials

Effect of Aminophylline Bolus Versus Infusion on Recovery Time in Patients Undergoing Lumbar Spine Surgery

Start date: December 30, 2022
Phase: Phase 4
Study type: Interventional

To determine optimal dose, method and time of administration of aminophylline to enhance the recovery from general anesthesia. andTo estimate the recovery time from isoflurane closure in each group. We hypothesize that starting administration of loading and maintenance dose of aminophylline half an hour before discontinuing isoflurane will shorten the duration needed to extubate patients undergoing lumbar disc surgery. We hypothesized that it will yield superior results compared to bolus administration after discontinuing isoflurane.

NCT ID: NCT05654649 Recruiting - Postoperative Ileus Clinical Trials

Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section

Start date: December 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Postoperative ileus is a perplexing problem for clinical surgeons. It occurs not only after abdominal surgery but also after any surgery that requires general anesthesia. Postoperative ileus is defined as the dysfunction of gastrointestinal motility after surgery, characterized by a decrease in, or stagnation of, intestinal peristalsis.