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NCT ID: NCT00460408 Completed - Clinical trials for Macular Degeneration

Ocular Safety Of Patients Receiving Macugen For Neovascular Age Related Macular Degeneration

Start date: August 2006
Phase: N/A
Study type: Observational

The study will provide additional safety data for specific safety events in persons receiving intravitreal injections. The Committee for Medicinal Products for Human Use (CHMP) is interested in obtaining additional safety information when Macugen is used in real world settings by practitioners in Europe treating patients with neovascular (wet) age-related macular degeneration (AMD). The study will provide information about physician practice patterns and characteristics of patients treated with Macugen.

NCT ID: NCT00459966 Completed - Spine Surgery Clinical Trials

Preoperative Prevention and Early Rehabilitation for Patients Undergoing Elective Spine Surgery

Start date: February 2005
Phase: N/A
Study type: Interventional

Aim: The aim is to evaluate the outcome after spine surgery when using an integrated program that combined preoperative prevention and early postoperative rehabilitation compared to the routine procedures. Outcome measurements: Postoperative hospital stay, complications, function, pain, and patient satisfaction. Method: 60 patients scheduled for surgery for degenerative lumbar disease. The control group followed the routines in the department. The intervention group followed the integrated program consisting of preoperative prevention.

NCT ID: NCT00459940 Completed - Clinical trials for Growth Hormone Deficiency

The Effects of TZD on Fat Metabolism and Insulin Sensitivity in GH-Replaced GHD Patients

Start date: September 2004
Phase: N/A
Study type: Interventional

In the present double blind, placebo-controlled, parallel study we evaluated the impact of 12 weeks thiazolidinedione (TZD) administration on basal and insulin-stimulated substrate metabolism in growth hormone-replaced adults with growth hormone deficiency.

NCT ID: NCT00459706 Completed - Clinical trials for Rheumatoid Arthritis

Study Comparing Perceptions and Satisfaction for Two Different Delivery Mechanisms for Etanercept

Start date: September 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to explore and compare the perceptions and satisfaction for two different delivery mechanisms for Etanercept (Etanercept Autoinjector and the Etanercept Prefilled Syringe) in patients with rheumatoid arthritis (RA).

NCT ID: NCT00459667 Completed - Clinical trials for Multiple Sclerosis, Relapsing-Remitting

BEYOND Follow-up: Betaferon®/Betaseron® Efficacy Yielding Outcomes of a New Dose

Beyond
Start date: May 2007
Phase: Phase 3
Study type: Interventional

The BEYOND Follow-Up study will give patients who participated in the preceding BEYOND study the opportunity to continue treatment with the 500µg dose of interferon beta (IFNB) 1b and will further investigate the safety and tolerability profile of interferon beta 1b 500µg during longer-term treatment.

NCT ID: NCT00459433 Completed - Low Back Pain Clinical Trials

The Right Intervention for the Right Patient

Start date: October 2006
Phase: N/A
Study type: Interventional

Complicated and expensive interventions are used to treat unspecific low back pain and the intervention is not always targeted the patients specific problems.It is therefore not surprising that a large fraction of unspecific low back pain patients do not respond very well to the usual biopsychosocial intervention. We would therefore like to identify the patients specific problems regarding the patients biomedical, psychological, and social needs.

NCT ID: NCT00458302 Completed - HIV Infections Clinical Trials

Treatment Simplification by Darunavir/Ritonavir 800/100 mg Once a Day Versus a Triple Combination Therapy With Darunavir/Ritonavir

MONET
Start date: June 2007
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare the efficacy, safety and tolerability of darunavir/ritonavir 800/100 mg once a day (O.D.) as a monotherapy versus a triple combination therapy containing 2 nucleosides and darunavir/ritonavir in 250 HIV-1 infected patients who have been on Highly Active Antiretroviral Therapy (HAART) and have plasma viral load below 50 copies/ml for at least 24 weeks.

NCT ID: NCT00457457 Completed - Clinical trials for Prostatic Hyperplasia

Study the Effects of Different Doses of UK-369,003 in Men With Lower Urinary Tract Symptoms.

Start date: May 2007
Phase: Phase 2
Study type: Interventional

This is a 12 week study in which different doses and formulations of UK-369,003 will be administered to patients with a diagnosis of enlarged prostate. Patients will complete a series of questionnaires before, during and after treatment to assess if UK-369,003 has improved their urinary symptoms and erectile function . There will be several blood samples taken during the study to asses the level of drug in the blood and correlate it with the responses to the questionnaires.

NCT ID: NCT00457392 Completed - Clinical trials for Carcinoma, Non-Small Cell Lung

A Study In Patients With Non-Small Cell Lung Cancer To Test If Erlotinib Plus SU011248 Is Better Than Erlotinib Alone

Start date: July 2007
Phase: Phase 3
Study type: Interventional

This study will test whether treatment with erlotinib plus SU011248 is better than erlotinib alone in patients with advanced/metastatic lung cancer who have received previous treatment with a platinum-based regimen.

NCT ID: NCT00457002 Completed - Pulmonary Embolism Clinical Trials

Study of Apixaban for the Prevention of Thrombosis-related Events in Patients With Acute Medical Illness

ADOPT
Start date: June 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to learn if apixaban can prevent blood clots in the leg (deep vein thrombosis [DVT]) and lung (pulmonary embolism [PE]) that sometimes occur within patients hospitalized for acute medical illness, and to learn how apixaban compares to enoxaparin (Lovenox®) for preventing these clots. The safety of apixaban will also be studied.