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NCT ID: NCT00758706 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

A Phase IIa Study Assessing the Effects of AZD1236 on Biomarkers in Chronic Obstructive Pulmonary Disease (COPD) Patients

BICO
Start date: September 2008
Phase: Phase 2
Study type: Interventional

The primary aim of this study is to investigate the effects of AZD1236 compared with placebo ("inactive substance") in COPD patients by analysing biomarkers for inflammation and tissue degradation in blood, urine and sputum.

NCT ID: NCT00757848 Completed - Cystic Fibrosis Clinical Trials

A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Cystic Fibrosis

INCA
Start date: October 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate if treatment with AZD9668 for 28 days is effective in treating Cystic Fibrosis (CF) and if so how it compares to placebo (a substance which does not have any action).

NCT ID: NCT00757237 Completed - Cystic Fibrosis Clinical Trials

Aztreonam for Inhalation Solution vs Tobramycin Inhalation Solution in Patients With Cystic Fibrosis & Pseudomonas Aeruginosa

Start date: August 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study was to assess the comparative safety and effectiveness of aztreonam for inhalation solution versus tobramycin inhalation solution in adult and pediatric patients with cystic fibrosis (CF) and pulmonary Pseudomonas aeruginosa (PA) infection.

NCT ID: NCT00756028 Completed - Quality of Life Clinical Trials

Short Versus Long Protocol for IVF and IVF+ICSI

KvL
Start date: January 2009
Phase: Phase 4
Study type: Interventional

Purpose: Comparing a GnRH agonist and an antagonist protocol for IVF/ICSI with regard to 1. frequency of ovarian hyperstimulation syndrome (OHSS) (1. outcome measure) 2. quality of life (2. outcome measure) 3. live birth rate (2. outcome measure) 4. gene expression profiles of granulosa and cumulus cells, and concentrations of estradiol and vascular endothelial growth factor in follicular fluid(not only compared between GnRH agonist and antagonist protocol, but also between patients with OHSS and no OHSS and patients becoming pregnant and not becoming pregnant (2. outcome measure), and 5. number of oocytes removed per treatment, number of embryo transfers per treatment and number of spontaneous abortions per treatment (these three parameters are tertiary outcome measures). In addition to the above mentioned efficacy outcome measures the safety outcome measure "frequency of known side-effects" will be compared between the two protocols.

NCT ID: NCT00755573 Completed - Clinical trials for Chronic Pancreatitis

Pain and Chronic Pancreatitis - Clinical End Experimental Studies

CPP
Start date: October 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study is to investigate the effect of pregabalin in pain resulting from chronic pancreatitis. The effect will be investigated by means of questionnaires concerning the daily experience of pain and the general quality of life. Furthermore the patients will be invited to participate in experimental testing with a multimodal pain model. The experimental testing will include stimulation of the skin, muscle and visceral tissue. The results from the experimental part of the study may help us to understand the mechanisms of action of pregabalin in this patient population.

NCT ID: NCT00753688 Completed - Clinical trials for Sarcoma, Soft Tissue

Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy

PALETTE
Start date: October 2008
Phase: Phase 3
Study type: Interventional

A randomized double blind phase III trial of Pazopanib versus placebo in patients with soft tissue sarcoma whose disease has progressed during or following prior therapy

NCT ID: NCT00751998 Completed - Clinical trials for Biliary Tract Diseases

Spy II Clinical Registry

Start date: November 2006
Phase:
Study type: Observational

A prospective, multi-center registry for subjects undergoing Endoscopic retrograde Cholangiopancreatography (ERCP) and cholangioscopy for known or suspected pancreaticobiliary disease.

NCT ID: NCT00751985 Completed - Alcohol Abuse Clinical Trials

Web-based Ultra-brief Intervention for Heavy Drinkers Trial

Start date: September 2008
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine whether a web-based ultra-brief intervention, consisting of personalized normative feedback or standardized self-help material, is effective in lowering self reported alcohol use in heavy drinkers.

NCT ID: NCT00751062 Completed - Ocular Hypertension Clinical Trials

A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinavia

Start date: November 1992
Phase: Phase 3
Study type: Interventional

PhXA41 is not inferior to timolol in reducing intra-ocular pressure

NCT ID: NCT00750984 Completed - Arthritis Clinical Trials

A Comparison of Two Different Surgical Techniques for Total Hip Resurfacing

Start date: September 2008
Phase: N/A
Study type: Interventional

This study compares the posterior approach to the anterolateral approach using the ReCap® Total Hip Resurfacing System.