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NCT ID: NCT03046186 Completed - Obesity, Morbid Clinical Trials

Physiological Effects of Gastric Sleeve Operation

Start date: June 2016
Phase:
Study type: Observational

After gastric sleeve patients undergo a substantial weight loss, but the physiological mechanisms behind the weight loss is not fully elucidated. Studies suggest that gut-hormone secretion is altered comparable to what is also seen after Roux-en-Y gastric bypass, however to which extent is not fully established and furthermore, the mechanisms behind an altered secretion are unclear. The purpose of this study is to investigate absorption and postprandial metabolism of glucose and protein in addition to gut hormonal responses after gastric sleeve compared with a group of un-operated subjects machted on sex, age and BMI. Furter, a group of Roux-en-Y gastric bypass operated patients matched on pre-operative BMI, current BMI, sex and age will be included for comparison.

NCT ID: NCT03044808 Completed - Opioid Use Clinical Trials

Investigation of the Effect of Intravenous Lidocaine Infusion on Postoperative Pain Treatment and Bowel Function in Robotic Bowel Surgery

Start date: February 2, 2016
Phase: Phase 4
Study type: Interventional

Single center double blind randomised controlled trial. 60 subjects. Giving lidocaine IV or saline to patients due to robot assisted colorectal surgery. Primary outcome is cumulative morphine consumption at 24 hours.

NCT ID: NCT03044288 Completed - Ileostomy - Stoma Clinical Trials

Evaluation of the Effect of Output on Skin Covered by a New Adhesive

Start date: January 23, 2017
Phase: N/A
Study type: Interventional

The study investigates the impact real output has on peristomal skin covered by a newly developed adhesive and a standard adhesive

NCT ID: NCT03044275 Completed - Ileostomy - Stoma Clinical Trials

The Influence of Output on Skin Covered by Adhesive With Topfilm

Start date: January 16, 2017
Phase: N/A
Study type: Interventional

The study investigates the impact real output has on peristomal skin covered by a newly developed adhesive with topfilm and a standard adhesive with a topfilm.

NCT ID: NCT03044262 Completed - Stoma Ileostomy Clinical Trials

Evaluation of the Influence of New Adhesives of Output on Skin

Start date: January 9, 2017
Phase: N/A
Study type: Interventional

The study investigates the impact real output has on peristomal skin covered by a newly developed adhesive and a standard adhesive

NCT ID: NCT03042793 Completed - Multiple Myeloma Clinical Trials

Vaccination With PD-L1 Peptide Against Multiple Myeloma

Start date: February 1, 2017
Phase: Phase 1
Study type: Interventional

Title: Vaccination with PD-L1 peptide with Montanide against multiple myeloma after high dose chemotherapy with stem cell support. A phase I first-in-human study. Hypothesis: In this trial the investigators assess a new immunotherapeutic strategy targeting the immune checkpoint molecule PD-L1 to investigate the potential of vaccination against PD-L1 as a possible anticancer target.

NCT ID: NCT03042364 Completed - Infertility, Female Clinical Trials

Cytokine Profile of the Uterine Secretome After Therapeutic Endometrial Scratching

Start date: October 1, 2016
Phase: N/A
Study type: Interventional

This study investigates the impact of endometrial scratching on endometrial secretion, when correlated to pregnancy.

NCT ID: NCT03042195 Completed - Clinical trials for Head and Neck Neoplasm

Supplementary Postoperative Parenteral Nutrition for Head and Neck Cancer Patients

SpPN-HNC
Start date: December 18, 2016
Phase: N/A
Study type: Interventional

The purpose of the study is to examine whether postoperative nutrition with endeavours of 100% coverage of the patient's estimated energy and protein needs, can reduce the incidence of postoperative complications.

NCT ID: NCT03040388 Completed - Depression Clinical Trials

Exploring Effects of Electroconvulsive Therapy on the Human Brain in Depression - The Danish ECT/MRI Study

Start date: August 9, 2017
Phase:
Study type: Observational

The main purpose of this study is to determine whether electroconvulsive therapy (ECT) causes any structural or functional brain changes and thus indicating its mechanism of action. The second aim is to find predictors of an immediate response, sustained remission, relapse and side-effects. Thirdly, this study aims to explore whether ECT causes any changes in blood-brain barriers permeability and whether these changes correlate to memory problems. The fourth objective is to examine whether ECT causes any brain tissue damage.

NCT ID: NCT03039114 Completed - Lymphoma Clinical Trials

Study Evaluating Safety and Efficacy of INCB050465 Combined With Bendamustine and Obinutuzumab in Relapsed or Refractory Follicular Lymphoma (CITADEL-102)

Start date: February 15, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of parsaclisib when combined with bendamustine and obinutuzumab in subjects with relapsed or refractory follicular lymphoma (FL).