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NCT ID: NCT03230786 Completed - Clinical trials for Type 2 Diabetes Mellitus

Study to Evaluate the Efficacy and Safety of KBP-042 in Patients With Type 2 Diabetes

Start date: August 23, 2017
Phase: Phase 2
Study type: Interventional

This is a multicentre, randomized, double-blind, placebo-controlled, parallel-group Phase II trial of twelve weeks of KBP-042 administered as daily s.c. injections in subjects with Type 2 Diabetes Mellitus with inadequate glycaemic control while treated with a stable dose of metformin. The trial is planned to be performed in Czech Republic, Denmark, Moldova, Poland, Romania and United Kingdom

NCT ID: NCT03229161 Completed - Clinical trials for Gestational Diabetes Mellitus in Pregnancy

Interval Walking Intervention for Pregnant Women Diagnosed With Gestational Diabetes Mellitus

Start date: January 3, 2017
Phase: N/A
Study type: Interventional

It is well-known that regular physical activity (PA) can improve glycemic control and physical fitness in type 2 diabetes patients. However, studies examining the effects of PA in patients with gestational diabetes mellitus (GDM) are limited. Interval walking training (IWT) is a careful type of PA consisting of repeatedly cycles of 3 min. fast and slow walking. The investigators aimed to examine, if IWT is feasible as PA intervention for GDM patients, and to examine the effects of IWT on glycemic control, PA levels and physical fitness.

NCT ID: NCT03228355 Completed - Headache, Migraine Clinical Trials

Headache Inducing Effect of Cromakalim in Migraine Patients

Start date: May 24, 2017
Phase: N/A
Study type: Interventional

To investigate the role of KATP channels on the cerebral hemodynamic in migraine patients.

NCT ID: NCT03226262 Completed - Clinical trials for Coronary Artery Disease

FFRangio Accuracy vs. Standard FFR

FAST-FFR
Start date: September 27, 2017
Phase:
Study type: Observational

This is a prospective, observational, multi-center, single-arm, clinical trial designed to assess the efficacy of FFRangio in measuring FFR obtained from angiography compared to Invasive FFR for diagnosing hemodynamically significant coronary stenosis.

NCT ID: NCT03225950 Completed - Clinical trials for Rheumatoid Arthritis

Interaction Between Immune Cells and Bacteria Associated With Periodontitis

Start date: February 1, 2017
Phase:
Study type: Observational

This study evaluates the interaction between host immune cells and bacteria associated with periodontitis. It comprises biological material from donors with and without periodontal disease. Specifically, we collect a spit and blood sample to conduct in vitro stimulations and measurements of selected parameters related to periodontitis to clarify obscure areas in the immunologic pathogenesis of this disease.

NCT ID: NCT03224702 Completed - Healthy Clinical Trials

First-in-Human Trial of Anti-ADAMTS-5 Nanobody in Healthy Volunteers

Start date: September 4, 2017
Phase: Phase 1
Study type: Interventional

This First-In-Human trial will be conducted in healthy male subjects to explore the safety, tolerability, immunogenicity, pharmacokinetics, and pharmacodynamics of single doses of M6495.

NCT ID: NCT03222232 Completed - Intestinal Failure Clinical Trials

Catheter Salvage in Intestinal Failure Patients

Start date: January 1, 2002
Phase: N/A
Study type: Observational

This is an observational study evaluating a catheter salvage strategy in relation to catheter-related bloodstream infections in patients with chronic intestinal failure dependent on home parenteral support. The study is confined to the period 2002 to 2016.

NCT ID: NCT03221699 Completed - Clinical trials for Microbiome of the Axillae

Effects of a Zinc Oxide Underarm Formula on Normal and Injured Skin in Healthy Volunteers

ZINC-ON
Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Bothersome odor from the axilla is in most cases caused by Corynebacterium spp. Anti-microbial effects of zinc oxide (ZnO) are well documented. The overall objective of this study is to verify that repeated applications of a ZnO containing formulation can be directly linked to reduced growth of Corynebacterium spp. in the axillae.

NCT ID: NCT03221686 Completed - Inguinal Hernia Clinical Trials

Effects of Oral Supplementation of Arginine, Zinc and Vitamin C on Collagen Synthesis in Inguinal Hernia Patients

Start date: February 20, 2016
Phase: N/A
Study type: Interventional

Collagen synthesis is depressed systemically in the immediate postoperative period. Arginine, zinc and vitamin C impact collagen synthesis. The aim of this study is to investigate the effect of a pre and postoperative oral supplement consisting of arginine, zinc and vitamin C on collagen synthesis in patients undergoing inguinal hernia repair.

NCT ID: NCT03220425 Completed - Clinical trials for Diabetes Mellitus, Type 1

Evaluation of the Efficacy and Safety of Insulin Detemir Compared With That of NPH Insulin in Subjects With Type 1 Diabetes.

Start date: February 1, 2001
Phase: Phase 3
Study type: Interventional

The aim of this trial is to evaluate the efficacy and safety of insulin detemir using the 2400 nmol/mL formulation to optimise dosing in subjects with type 1 diabetes on a basal (once daily)-bolus regimen.