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NCT ID: NCT01499667 Terminated - Clinical trials for Relapsing Remitting Multiple Sclerosis (RRMS)

Disease Control and Safety in Patients With Relapsing Remitting Multiple Sclerosis (RRMS) Switching From Natalizumab to Fingolimod

TOFIINGO
Start date: September 2011
Phase: Phase 3
Study type: Interventional

This study evaluated disease control during different lengths of treatment transition from natalizumab to fingolimod.

NCT ID: NCT01499355 Terminated - Lupus Nephritis Clinical Trials

BIIB023 Proof-of-Concept Study in Participants With Lupus Nephritis

ATLAS
Start date: July 2012
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to assess the efficacy of BIIB023 as an add-on treatment to background therapy compared with placebo in combination with background therapy in the treatment of participants with active, biopsy-proven Lupus Nephritis. The secondary objectives of this study are to assess the safety and tolerability of BIIB023 compared with placebo in this study population. Participants who complete this study through Week 52 will be offered the option to enter an Extension study under a separate protocol 211LE202 (NCT0193089).

NCT ID: NCT01497171 Terminated - Clinical trials for Pelvic Organ Prolapse

The ELEGANT Trial: Elevate Transvaginal Mesh vs. Anterior Colporrhaphy

Start date: November 2011
Phase: Phase 4
Study type: Interventional

This study is designed to compare the safety and efficacy of a commercially available mesh kit used for surgical repair of anterior vaginal wall prolapse with traditional suture repair surgery.

NCT ID: NCT01493505 Terminated - Ovarian Cancer Clinical Trials

TRINOVA-3: A Study of AMG 386 or AMG 386 Placebo in Combination With Paclitaxel and Carboplatin to Treat Ovarian Cancer

Start date: January 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether AMG 386 or AMG 386 Placebo in combination with Paclitaxel and Carboplatin are effective in the treatment of ovarian cancer.

NCT ID: NCT01491854 Terminated - Clinical trials for Short Children Born Small for Gestational Age (SGA)

Long-term Safety Follow-up After Growth Hormone Treatment of Short Children Born Small for Gestational Age

SGA
Start date: July 20, 2009
Phase: N/A
Study type: Interventional

This study is performed as part of the Marketing Authorisation Holder's post-marketing pharmacovigilance plan to investigate the long-term safety, in particular the diabetogenic potential and immunogenicity of rhGH therapy in short children born small for gestational age (SGA).

NCT ID: NCT01490827 Terminated - Clinical trials for Retinitis Pigmentosa

Argus® II Retinal Prosthesis System Post-Market Surveillance Study

Start date: November 2011
Phase:
Study type: Observational

This post-market surveillance study is conducted in the European Economic Area where Argus II has been CE certified for use in outer retinal degeneration patients.

NCT ID: NCT01487083 Terminated - Schizophrenia Clinical Trials

A Long-Term Study in Schizophrenia

Start date: December 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the long-term safety of pomaglumetad methionil in participants with schizophrenia.

NCT ID: NCT01485432 Terminated - Clinical trials for Renal Transplant Surgery

Goal Directed Hemodynamic Management and Renal Outcome After Renal Transplant Surgery

IROR
Start date: October 2011
Phase:
Study type: Observational

This study is designed to compare the incidence of delayed graft function in patients following renal transplant surgery with different perioperative hemodynamic managements: a goal directed hemodynamic management group (using PiCCO) and a control group.

NCT ID: NCT01485094 Terminated - Neuralgia Clinical Trials

A Study to Assess the Safety and Efficacy of 7 Days Treatment With a Novel Analgesic in Subjects With Peripheral Neuropathic Pain

Start date: February 2012
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to determine whether a novel analgesic is effective in treating of neuropathic pain caused by herpetic infection, surgery, or trauma.

NCT ID: NCT01483183 Terminated - Atrial Fibrillation Clinical Trials

Ascending Dose Study of OPC-108459 Intravenous Infusions in Patients With Paroxysmal and Persistent Atrial Fibrillation

CADENCE 215
Start date: November 2011
Phase: Phase 1
Study type: Interventional

The purpose of Part 1 of this study is to determine the maximally tolerated dose of OPC-108459 in patients with paroxysmal and persistent atrial fibrillation (AF). The purpose of Part 2 of this study is to determine potential efficacy of dose(s) of OPC-108459 for the treatment of paroxysmal and persistent atrial fibrillation.