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NCT ID: NCT04972669 Recruiting - Clinical trials for Postprostatectomy Incontinence

The Study of Electrical Acupuncture Stimulation Therapy for Postprostatectomy Incontinence

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

More than 50% patients underwent prostatectomy suffered from postoperative incontinence, and the effect of pelvic floor muscle training is very limited. Electrical acupuncture stimulation therapy has been demonstrated to work on other kinds of Urinary Incontinence. Before this trial, the researchers have conducted pre-experiments where electrical acupuncture stimulation therapy was conducted for few postprostatectomy Incontinence patients. On the basis of the preliminary work, this prospective, random control research aims to verify the safety and effectiveness of electroacupuncture in the treatment of postprostatectomy Incontinence.

NCT ID: NCT04972656 Recruiting - Clinical trials for Pulmonary Arterial Hypertension

Treatment With Ambrisentan in Patients With Borderline Pulmonary Arterial Hypertension

TAPE
Start date: September 5, 2022
Phase: N/A
Study type: Interventional

An Investigator initiated trial (IIT) using a prospective, randomized, double-blind, parallel group, placebo-controlled, clinical study design.

NCT ID: NCT04972591 Recruiting - Healthy Clinical Trials

Follow-up Study of Population Vaccinated With COVID-19 Vaccine

Start date: March 15, 2021
Phase:
Study type: Observational

A multi-centered clinical follow-up study to investigate the long-term dynamic of COVID-19 antibody level after vaccination.

NCT ID: NCT04972422 Recruiting - Solid Tumors Clinical Trials

A Phase 1b Study of ZN-c3 in Chinese Subjects

Start date: July 15, 2021
Phase: Phase 1
Study type: Interventional

This is a Phase 1b open-label, multicenter study, evaluating the safety, tolerability, efficacy, pharmacokinetics (PK) and pharmacodynamics of ZN c3.

NCT ID: NCT04972201 Recruiting - Cancer Clinical Trials

A Proof of Concept Study of Pan-cancer Early Detection by Liquid Biopsy

PROMISE
Start date: July 5, 2021
Phase:
Study type: Observational

PROMISE is a multi-center, prospective and proof of concept study aimed to evaluate the performance of 3 prototype assays of cell-free DNA (cfDNA) mutation, cfDNA methylation and microRNA (miRNA) expression in early detection of multi-cancer. Assay(s) will be selected for further development. The study will enroll approximately 2035 participants, including participants with cancers and healthy participants.

NCT ID: NCT04972032 Recruiting - Clinical trials for Intrauterine Adhesion

Efficacy of Estrogen-intrauterine Stent System After Intrauterine Adhesiolysis

Start date: September 2, 2020
Phase: N/A
Study type: Interventional

This is a prospective, randomized, single-blinded,multi-center trial to compare the efficacy of an Estrogen-intrauterine stent system with foley balloon combined with intrauterine cross-linked sodium hyaluronate gel in the prevention of intrauterine adhsion recurrence after hysteroscopic adhesiolysis.

NCT ID: NCT04971980 Recruiting - Clinical trials for Rheumatoid Arthritis

Safety and Efficacy Study of Human Umbilical Cord-Derived Mesenchymal Stem Cells(BC-U001) for Rheumatoid Arthritis

Start date: April 12, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

BC-U001 is an allogeneic fresh human umbilical cord-derived mesenchymal stem cell product, which showed therapeutic potential for rheumatoid arthritis(RA) based on its anti-inflammatory, immunomodulatory and tissue repair activities. The primary objective of this open-label, non-randomized, dose-escalation study is to evaluate the safety and tolerability of a single intravenous infusion of BC-U001 for RA patients using a 3+3 design.

NCT ID: NCT04971616 Recruiting - Low Back Pain Clinical Trials

Risk Screening and Assessment of Shoulder, Neck and Lower Back Discomfort.

Start date: August 1, 2020
Phase:
Study type: Observational

Identifying high-risk factors that may lead to shoulder, neck and lower back discomfort and contributing to the primary prevention of disease progression.

NCT ID: NCT04971122 Recruiting - Clinical trials for The Angle of Trendelenburg

Comparison of the Effects of Trendelenburg Position and Passive Leg Lift on Hemodynamics in Abdominal Surgery Patients

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

How to maintain the stability of circulation during anesthesia has always been a concern of clinicians, including shorting the preoperative fasting time under the condition of full preoperative preparation, and giving appropriate amount of nutrient solution in combination with the patient's situation 2~4 h before surgery to reduce the blood volume insufficiency of patients before general anesthesia induction, vasoactive drugs, etc. Among them, passive leg lifting experiment is widely recognized in the world. Although passive leg lifting has many advantages, it still has some limitations in the operation process. This study tried to find the corresponding head low and foot high Angle corresponding to the same hemodynamic changes caused by passive leg lifting.

NCT ID: NCT04970914 Recruiting - Colorectal Cancer Clinical Trials

Anlotinib Plus Penpulimab (AK105) for Chemo-refractory Metastatic Colorectal Cancer:ALTER-C003

ALTER-C003
Start date: November 5, 2021
Phase: Phase 2
Study type: Interventional

A single-arm, open-label clinical trial, focus on the safety and efficacy of anlotinib hydrochloride in combination with Penpulimab (AK105) in patients with Chemo-refractory Metastatic Colorectal Cancer (mCRC)