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NCT ID: NCT05593250 Enrolling by invitation - Asthma Clinical Trials

A Trial of SHR-1905 in Subjects With Severe Uncontrolled Asthma

Start date: January 17, 2023
Phase: Phase 2
Study type: Interventional

This study is a phase 2 study of SHR-1905 in subjects with severe uncontrolled asthma. The purpose of the study is to evaluate efficacy and safety of SHR-1905 in subjects with severe uncontrolled asthma.

NCT ID: NCT05593224 Not yet recruiting - Clinical trials for Intracranial Atherosclerosis

The Efficacy and Safety of Intracranial Stent (Tonbridge) in Endovascular Treatment of Intracranial Atherosclerotic Stenosis

Start date: November 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to verify the efficacy and safety of the Intracranial Stent (Tonbridge) in endovascular treatment of intracranial atherosclerotic stenosis.

NCT ID: NCT05593146 Recruiting - Clinical trials for Periacetabular Tumor

A Randomized Controlled Study Evaluating Modified Cup Anteversion Placement in Prevention of Postoperative Dislocation in Patients Undergoing Acetabular Tumor Resection and Reconstruction

Start date: April 13, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this clinical study is to investigate whether patients who receive modified anteversion angle (( α-15°)±10°) of the acetabular cup have a lower risk of dislocation within one year after surgery, compared to patients who receive conventional anteversion angle ( α±10°) of the acetabular cup. The hypothesis is that patients with placement of the modified (( α-15°)±10°) anteversion angle of the acetabular component will have decreased risk of dislocation 1 year after surgery compared to patients with conventional anteversion angle ( α±10°) placement. PS: α refers to the preoperative anteversion angle of the affected hip. α equals to the anteversion angle of the contralateral limb if it cannot be accurately measured on the affected limb. A standard error within 10° is accepted

NCT ID: NCT05593120 Recruiting - Clinical trials for Coronary Artery Disease

Evaluation of Health Economics for Noninvasive Coronary Fractional Flow Reserve Measurement Technology

Start date: June 29, 2022
Phase:
Study type: Observational

To determine whether, in a Chinese population of patients presenting to Wuhan Asia Heart Hospital, Fractional Flow Reserve Derived from Coronary Computed Tomography Angiography (CT-FFR) as a default test is noninferior in terms of total costs when compared to routine clinical pathway recommended by the investigator and the institution's heart team.

NCT ID: NCT05593107 Recruiting - Neoplasms Clinical Trials

68Ga-N188 PET/CT Imaging in Malignancy

Start date: August 12, 2022
Phase: N/A
Study type: Interventional

The Nectin-4 protein belongs to the cell adhesion factors family and has a tissue-specific expression spectrum in normal human tissues. However, Nectin-4 is overexpressed in various malignancies, especially those of epithelial origins, such as uroepithelial carcinoma, making Nectin-4 a highly specific and significant imaging target for malignancies. [68Ga]N188, a novel molecular probe of PET imaging agent that targets Nectin-4, can be used in the diagnosis and research of a wide variety of Nectin-4 high-expression malignancies, including bladder cancer.

NCT ID: NCT05593081 Recruiting - Clinical trials for Diabetes Mellitus, Type 1

Multicenter Study of Fulminant Type 1 Diabetes in China

Start date: May 20, 2022
Phase:
Study type: Observational [Patient Registry]

This study took FT1D(fulminant type 1 diabetes) as the research object, collected the cases of FT1D patients, and described the clinical characteristics of this type of disease. The HLA susceptibility genes of FT1D were identified by PCR and other techniques, taking age-sex-matched healthy subjects as controls and HLA genes as the research entry point.

NCT ID: NCT05592925 Recruiting - Clinical trials for Lymph Node Metastasis

Association Between Multiple Coagulation-related Factors and Lymph Node Metastasis in Patients With Gastric Cancer: A Retrospective Cohort Study

MA
Start date: January 1, 2018
Phase:
Study type: Observational

We initially selected a total of 1128 patients with primary gastric cancer who presented at Shandong Provincial Hospital between January 2018 and October 2022, and retrospectively collected their clinical and pathological data. And retrospectively analyzed preoperative baseline characteristics, preoperative laboratory tests, and postoperative pathological results for these patients

NCT ID: NCT05592795 Active, not recruiting - Choledocholithiasis Clinical Trials

Explore the Effects and Mechanisms of ERCP and EST on Biliary Microecology

Start date: September 1, 2022
Phase:
Study type: Observational [Patient Registry]

The objective of this observational study is to explore the structure of biliary flora in normal people, explore the dynamic impact of ERCP and EST on biliary microecology, study the marker flora, metabolites and functional genes related to biliary diseases, explore the occurrence and development mechanism, regulatory pathways and key targets of biliary diseases, and provide new strategies for the prevention and treatment of biliary diseases from the perspective of biliary microecology.

NCT ID: NCT05592717 Recruiting - Uveitis Clinical Trials

A Study of YUTIQ® 0.18 mg Intravitreal Implant for the Management of Chronic Non-infectious Uveitis

Start date: January 5, 2023
Phase:
Study type: Observational

This project is designed to evaluate the efficacy of YUTIQ® 0.18 mg intravitreal implant for the management of chronic non-infectious uveitis.

NCT ID: NCT05592262 Completed - Malignant Tumor Clinical Trials

Pharmacokinetic Test of High-fat Diet After Oral Administration of SHR2554 in Healthy Subjects

Start date: November 15, 2022
Phase: Phase 1
Study type: Interventional

The objective of the study is to assess the effect of food on the pharmacokinetics, and safety of SHR2554 Tablets in healthy subjects.