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NCT ID: NCT05620589 Not yet recruiting - Clinical trials for Helicobacter Pylori Infection

The Effect of Time Intervals for Rescue Treatment on Eradication Effect of Helicobacter Pylori Infection

Start date: November 11, 2022
Phase:
Study type: Observational

The researchers collect patients who accepted eradication program of the helicobacter pylori but failed to eradicate helicobacter pylor from the outpatient clinic. After rescue therapy, evaluating the effect of retreatment interval on eradication effect of Helicobacter pylori infection.

NCT ID: NCT05620537 Completed - Prognosis Clinical Trials

A Novel Nomogram to Predict the Postoperative Overall Survival in Gastrointestinal Cancer Patients

Start date: November 10, 2022
Phase:
Study type: Observational

This multicenter retrospectively observational cohort study was conducted on participants with histologically confirmed gastric and colorectal cancer who underwent radical surgery in 11 medical centers in China from August 1, 2015, to June 31, 2018. Baseline clinicopathologic data and nutritional status assessments including Nutrition Risk Screening 2002 (NRS 2002) score and Patient-generated Subjective Global Assessment (PG-SGA) rating were collected. Variables will be screened using the least absolute shrinkage and selection operator (LASSO) regression model and Cox regression analysis. Internal and external validations will be performed via the receiver operating curve (ROC), the area under the curve (AUC), the concordance index (C-index), calibration plots, decision curve analysis (DCA), and Five folds cross-validation by 200 times.

NCT ID: NCT05620498 Recruiting - Clinical trials for Potentially Resectable Locally Advanced Intrahepatic Cholangiocarcinoma and Gallbladder Cancer

Tislelizumab Combined With Lenvatinib and GEMOX Versus Tislelizumab Combined With GEMOX in Conversion Therapy of ICC and GBC.

Start date: September 8, 2022
Phase: Phase 2
Study type: Interventional

This is an Open Phase II Clinical Study of Tislelizumab Combined with Lenvatinib and GEMOX Versus Tislelizumab Combined with GEMOX in the Treatment of Locally Advanced Intrahepatic Cholangiocarcinoma and Gallbladder Cancer.

NCT ID: NCT05620420 Recruiting - Insomnia Clinical Trials

A Multicenter Cross-sectional Study on Mental Health of Patients With Multiple Myeloma

Start date: November 15, 2022
Phase:
Study type: Observational

Multiple myeloma patients with normal ability of communication and understanding will be enrolled. DT, GAD-7, PHQ-15 and PSQI scales are designed to assess the mental health status of the patients. Demographic and disease data of patients will be collected as well. The main aim is to explore the factors affecting the mental health of myeloma patients.

NCT ID: NCT05620355 Recruiting - Uterine Fibroids Clinical Trials

Efficacy and Safety of BG2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids.

Start date: December 16, 2022
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to demonstrate the superior efficacy versus placebo of BG2109 alone and in combination with add-back therapy for the reduction of heavy menstrual bleeding associated with uterine fibroids in premenopausal women.

NCT ID: NCT05620160 Completed - Clinical trials for Mild to Moderate COVID-19

Study of RAY1216 Tablets Compared With Placebo in Patients With Mild to Moderate COVID-19

Start date: November 12, 2022
Phase: Phase 3
Study type: Interventional

This is a multi-center, randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of RAY1216 tablets in the treatment of mild to moderate SARS-CoV-2 infection. The total study duration is up to 28 days.

NCT ID: NCT05620095 Recruiting - Clinical trials for Peripheral Artery Disease

Durg Coated Balloon Angioplasty in Infrapopliteal Lesions

Act
Start date: December 1, 2020
Phase:
Study type: Observational [Patient Registry]

This study is a multicenter observational study designed to evaluate the the effectiveness and safety of drug-coated balloon (DCB) angioplasty for below the knee arterial lesions in patients critical with Limb Threatening Ischemia (CLTI).

NCT ID: NCT05620056 Completed - Pregnancy Clinical Trials

A Population-based Study of Drug Exposures and Adverse Pregnancy Outcomes in China (DEEP)

Start date: January 1, 2013
Phase:
Study type: Observational

The DEEP cohort is the first population-based cohort of pregnant population in China that longitudinally documents drug uses throughout the pregnancy life course and adverse pregnancy outcomes.

NCT ID: NCT05620004 Recruiting - Clinical trials for Advanced Hepatocellular Carcinoma

Safety and Efficacy of Bifidobacterium Therapy in Patients With Advanced Liver Cancer Receiving Immunotherapy

Start date: November 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This study plans to observe the changes of liver cancer and immune cell subsets by replicating the high abundance intestinal flora and liver cancer mouse model, reveal the relationship and mechanism of intestinal flora in the immunotherapy of liver cancer, and study the impact on prognosis by regulating the positive correlation of lactic acid bacteria and bifidobacteria of rumen coccus in patients with advanced liver cancer receiving immunotherapy

NCT ID: NCT05619926 Completed - Hemophilia Clinical Trials

Safety and Efficacy of STSP-0601 in Adult Patients With Hemophilia A or B Without Inhibitor

Start date: January 9, 2023
Phase: Phase 2
Study type: Interventional

This study will assess the safety,efficacy,pharmacokinetics and pharmacodynamics of multiple-dose of STSP-0601 at two dose levels for the treatment of bleeding episodes in hemophilia A or B patients without inhibitor.