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NCT ID: NCT05842798 Completed - Healthy Volunteers Clinical Trials

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TNM002 in Chinese Healthy Adults

Start date: October 15, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics properties of TNM002 following a single intramuscular dose in Chinese healthy adults.

NCT ID: NCT05841940 Completed - Clinical trials for Mass Balance Study in Healthy Subjects

Mass Balance Study of [14C]HLX208 in China Healthy Subjects

Start date: June 17, 2023
Phase: Phase 1
Study type: Interventional

Mass Balance Study of [14C]HLX208 in China Healthy Subjects.

NCT ID: NCT05841446 Completed - Healthy Clinical Trials

Bioequivalence Study of Apixaban Tablets in Healthy Chinese Subjects

Start date: March 2, 2021
Phase: Phase 1
Study type: Interventional

To evaluate the single-center, open, randomized, single-dose, two-cycle, two-sequence, cross-over bioequivalence of test preparation apixaban tablet 2.5mg and reference preparation 2.5mg in healthy adult subjects in fasting and fed state

NCT ID: NCT05841394 Completed - Clinical trials for Stress Ulcer Bleeding

A Multi-center, Double-blinding, Parallel and Positive-controlled Phase III Clinical Trial for Efficacy and Safety Evaluation of Ilaprazole Sodium for Injection on Prevention of Stress Ulcer Bleeding

Start date: July 16, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of the study drug (Ilaprazole Sodium for Injection) for potential effect on preventing stress ulcer bleeding in vulnerable population by comparing the radio of upper gastrointestinal bleeding when they are administered Ilaprazole Sodium for Injection and Esomeprazole Sodium for Injection respectively.

NCT ID: NCT05841329 Completed - Clinical trials for Transcranial Direct Current Stimulation

Efficacy of tDCS to Enhance Virtual Reality Exposure Therapy Response in Acrophobia

Start date: August 6, 2020
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to examine whether transcranial direct current stimulation(tDCS) can enhance the effect of virtual reality exposure therapy(VRET) in acrophobia in college students with significant fear of heights. The main question it aims to answer are: • the enhancement of tDCS on the effect of VRET Participants will randomly allocated to tDCS active stimulated group and sham stimulated group and receive VRET.

NCT ID: NCT05841043 Completed - Dry Eye Disease Clinical Trials

Efficacy and Safety of SHR8028 Eye Drops for the Treatment of Dry Eye Disease

Start date: March 4, 2021
Phase: Phase 3
Study type: Interventional

The study is being conducted to assess the efficacy, safety and tolerability of SHR8028 eye drops in comparison to the vehicle for the treatment of dry eye disease.

NCT ID: NCT05839639 Completed - Chronic Hepatitis B Clinical Trials

A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With HBeAg-Negative Chronic Hepatitis B Treated With Nucleos(t)Ide Reverse Transcriptase Inhibitors

Start date: October 9, 2021
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, controlled Phase IIa study of HH-003 injection, HH-003 injection is a monoclonal antibody targeting Hepatitis B virus. This study aims to evaluate the antiviral activity and safety in subjects with with HBeAg-negative Chronic Hepatitis B treated with nucleos(t)ide reverse transcriptase inhibitors.

NCT ID: NCT05839288 Completed - Breast Cancer Clinical Trials

Pyrotinib Plus Trastuzumab and Chemotherapy in HER2+ Metastatic Breast Cancer Patients

Start date: November 1, 2022
Phase:
Study type: Observational

To evaluate the patterns and treatment outcomes of pyrotinib plus trastuzumab and chemotherapy in the real world.

NCT ID: NCT05839158 Completed - Wound Heal Clinical Trials

Evaluation of the Effect of HFMT in Promoting Donor-site Wound Healing

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Autologous hair transplantation involves follicle extraction, trimming, and implantation. Follicle trimming improves efficiency and postoperative appearance, resulting in the discarded tissue known as hair follicle-derived microtissue (HFMT). In a clinical case, HFMT homogenate was applied to the FUE donor area wound, resulting in reduced pain, relief from itching, and faster healing compared to conventional treatment. This study aims to compare the effects of HFMT on FUE donor area wound healing.

NCT ID: NCT05838885 Completed - Turner Syndrome Clinical Trials

A Trial of YPEG-rhGH in Children With Short Stature

Start date: February 15, 2022
Phase: Phase 2
Study type: Interventional

To explore the dose-response relationship between pharmacokinetics and pharmacodynamics of Y- Shaped Pegylated growth hormone injection (YPEG-GH) in children with short stature (idiopathic short stature (ISS), small for gestational age (SGA), Turner syndrome (TS)). To evaluate its tolerability, safety and efficacy and to provide evidence for dose selection and titration for future clinical development and clinical application in these population.