Clinical Trials Logo

Filter by:
NCT ID: NCT05661097 Recruiting - Clinical trials for Abdominal Wall Hernia

Clinical Study of Hernia Ring Closure Method in Laparoscopic Abdominal Wall Hernia Repair

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

By comparing the time of closing the hernia ring, the degree of pain, and the recovery of gastrointestinal tract in different groups Intervening, infection, recurrence and medical cost, to find out whether patients with abdominal wall hernia have different hernias It is the best way to close the hernia ring under laparoscopy and provide evidence based medicine. with In the research process of the research group, a database on abdominal wall hernia will be established for the future Further study of hernia has laid a solid foundation.

NCT ID: NCT05660915 Recruiting - Pancreatic Cancer Clinical Trials

A Prospective Clinical Study Using an Artery-first Intermediate Approach in Robot-assisted Pancreaticoduodenectomy

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Pancreaticoduodenectomy, as a standard surgical procedure for malignant tumors of the head of the pancreas, ampulla and distal common bile duct, has brought the hope of clinical cure for these diseases.In the whole surgical process, the resection of the uncinate process of the pancreas is considered to be a major difficulty in the whole operation, which can affect the rehabilitation process and long-term prognosis. Two main methods have been developed around the dissection of the uncinate process of the pancreas. One is the Venous-first approach based on the portal vein-superior mesenteric vein axis. The other is the Artery-first approach that first explores whether the superior mesenteric artery is invaded by the tumor to judge resectable. The latter is gradually promoted in clinical practice because it can reduce intraoperative bleeding, reduce postoperative complications, and improve long-term prognosis. The intermediate approach is a surgical approach based on the Artery-first approach and adapted to the layout of the robot arm. The area between superior mesenteric artery and superior mesenteric vein was used as an intermediate area to treat the uncinate process of the pancreas in order to reduce perioperative complications and achieve better surgical results. However, the safety and effectiveness of intermediate approach have not been verified,in this prospective clinical study, the investigators will use a robotic surgical platform to perform robot-assisted pancreaticoduodenectomy surgery through the intermediate approach to verify its safety and efficacy.

NCT ID: NCT05660785 Recruiting - Untreated Clinical Trials

Herombopag Added to Cyclosporine in Non Severe Aplastic Anemia

Start date: December 1, 2022
Phase: Phase 2
Study type: Interventional

This is a prospective, multicenter, single-arm, phase 2 trial. The aim of this study is to evaluate the efficacy and safety of herombopag combined with cyclosporine for patients with non severe aplastic anemia (NSAA).

NCT ID: NCT05660720 Active, not recruiting - Healthy Subject Clinical Trials

Evaluate the Effect of Orelabrutinib on Cardiac Repolarization in Healthy Subjects

Start date: November 19, 2022
Phase: Phase 1
Study type: Interventional

This is A Randomized, Blinded, Placebo- and Positive-Controlled, Four-Period, Crossover-Design Thorough QT/QTc (TQT) Study to Evaluate the Effect of Orelabrutinib on Cardiac Repolarization in Healthy Subjects

NCT ID: NCT05660473 Recruiting - Clinical trials for Precursor Cell Lymphoblastic Leukemia-Lymphoma

Pediatric-inspired Regimen Combined With Venetoclax for Adolescent and Adult Patients With de Novo Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Start date: October 31, 2022
Phase: Phase 2
Study type: Interventional

The pediatric-inspired regimen has greatly improved the prognosis of adult patients with with Philadelphia chromosome-negative acute lymphoblastic leukemia (Ph- ALL), but relapse remains a great challenge. Venetoclax (Ven) is an oral, selective inhibitor of B-cell lymphoma 2 (Bcl-2). Although this drug is currently used primarily for acute myeloid leukemia, in vitro as well as small cohort studies suggest a effect in acute lymphoblastic leukemia. This study proposes to combine pediatric-inspired regimen with venetoclax for the treatment of adult patients with Ph- ALL, aiming to improve the MRD-negative complete remission rate measured by flow cytometry after induction and to reduce relapse, thus further improving patients overall survival.

NCT ID: NCT05659992 Recruiting - Clinical trials for Acute Myeloid Leukemia

Clinical Study of Venetoclax Combined With CACAG Regimen in the Treatment of Newly Diagnosed Acute Myeloid Leukemia

Start date: January 10, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of venetoclax combined with CACAG regimen in the treatment of newly diagnosed acute myeloid leukemia.

NCT ID: NCT05659940 Recruiting - Clinical trials for Corneal Neovascularization

Correlation Between a Novel Subset of Neutrophil and Corneal Neovascularization.

Start date: January 1, 2023
Phase:
Study type: Observational

The purpose of this study is to determine whether a novel subset of neutrophils is correlated with corneal neovascularization in the patients suffered from ocular chemical injury.

NCT ID: NCT05659927 Active, not recruiting - Asthma Clinical Trials

Single Dose Clinical Trial of MG-ZG122 in Chinese Healthy Adult Subjects

Start date: February 9, 2023
Phase: Phase 1
Study type: Interventional

To determine the safety and tolerability of MG-ZG122 in Chinese healthy adult subjects

NCT ID: NCT05659654 Completed - COVID-19 Clinical Trials

The Application of Ursodeoxycholic Acid for the Prevention of SARS-CoV-2 Infection (COVID-19)

Start date: December 16, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Evaluation of the efficacy and safety of ursodeoxycholic acid in blocking the transmission of infectious novel coronaviruses in a population of medical workers

NCT ID: NCT05659641 Enrolling by invitation - Clinical trials for Cardiovascular Diseases

The Branch-based Intraoperative Stent System in the Treatment of Stanford A Aortic Dissection(BROAD)

BROAD
Start date: January 18, 2023
Phase: N/A
Study type: Interventional

The purpose of the study was to evaluate the safety and efficacy of a branched type intraoperative stent system for the treatment of Stanford type A aortic dissection