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NCT ID: NCT05297682 Recruiting - Anesthesia Clinical Trials

Effects of Repeated Intravenous Anesthesia With Propofol on the Postoperative Neurological Function of Patients Undergoing Hysteroscopic Surgery

Start date: April 1, 2022
Phase:
Study type: Observational

Perioperative neurocognitive disorders(PND) is a common complication during the perioperative period, which affects the patient's rehabilitation and quality of life. Animal studies have found that repeated anesthesia and operation lead to neurological disorders. However, there is currently a lack of clinical studies on the effects of repeated anesthesia on patients' neurological function. With the full liberalization of China's three-child policy, the number of women in need of childbearing has increased, and infertile women who repeatedly undergo hysteroscopic surgery under intravenous anesthesia is increasing . Therefore, it is of great significance to investigate whether repeated and repeated general anesthesia and hysteroscopic surgery affect the patient's neurological function. The purpose of this study is to explore the effect of repeated propofol intravenous anesthesia on the neurological function of patients undergoing hysteroscopic surgery.

NCT ID: NCT05297552 Recruiting - Clinical trials for Muscle Invasive Bladder Carcinoma

A Study of RC48-ADC Combined With JS001 For Perioperative Treatment of Muscle-Invasive Bladder Cancer

Start date: May 26, 2022
Phase: Phase 2
Study type: Interventional

This study will evaluate the efficacy and safety of intravenous RC48-ADC combined with JS001 in perioperative treatment of muscle-invasive bladder cancer.

NCT ID: NCT05297474 Recruiting - Systemic Sclerosis Clinical Trials

Structural and Functional Impairment of Multiple Organs in Patients With Systemic Sclerosis: A MR Imaging Study

Start date: July 1, 2021
Phase:
Study type: Observational

This study intends to carry out a prospective, multi-center cohort study based on MRI to explore the incidence of structural and functional damage of central, brain and kidney in patiant with SSc and its clinical relevance, and to search for the characteristics of serological markers of structural and functional damage of heart, brain and kidney.

NCT ID: NCT05297292 Recruiting - Clinical trials for Wet Age-related Macular Degeneration

A Study to Evaluate the Efficacy and Safety of MW02 in the Treatment of nAMD

Start date: May 7, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of MW02 versus Lucentis in the treatment of neovascular age-related macular degeneration.The study was divided into two stages. The first stage was to explore the dose and the second stage was to explore the frequency of administration.

NCT ID: NCT05297123 Recruiting - Clinical trials for Acute Myeloid Leukemia

Treatment of Acute Myeloid Leukemia With Arsenic and All-trans Retinoid Acid

Start date: February 3, 2019
Phase: Phase 1
Study type: Interventional

The clinical trial was designed to prove that Arsenic plus ATRA possibly had an effect on improving the symptoms, reducing the early mortality rate and prolonging the total survival time of patients with newly diagnosed or relapsed AML.

NCT ID: NCT05296876 Recruiting - Carotid Stenosis Clinical Trials

SSPC Evaluation on Carotid Artery Stenosis After Endarterectomy

SSPC
Start date: April 1, 2022
Phase:
Study type: Observational [Patient Registry]

SSPC includes degree of Stenosis, Symptoms, Plaque stability and Compensation of the cerebral blood flow. SSPC, a comprehensive evaluation system on carotid artery stenosis, is established and advocated in this trial in order to make assessment on risk of carotid revascularization preoperatively and prediction of cerebral events postoperatively.

NCT ID: NCT05296798 Recruiting - Clinical trials for Locally Advanced or Metastatic Breast Cancer

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

Start date: July 4, 2022
Phase: Phase 3
Study type: Interventional

This Phase III, randomized, two-arm, open-label, multicenter study will evaluate the efficacy and safety of giredestrant plus Phesgo compared with Phesgo after induction therapy with Phesgo plus taxane in participants with human epidermal growth factor receptor 2 (HER2)-positive, estrogen receptor (ER)-positive advanced breast cancer (metastatic or locally advanced disease not amenable to curative treatment) who have not previously received a systemic non-hormonal anti-cancer therapy in the advanced setting.

NCT ID: NCT05296603 Recruiting - Clinical trials for Small Cell Lung Cancer

Efficacy and Biomarker Explanation of IBI-322 Plus Lenvatinib on Extensive Stage Small Cell Lung Cancer

Start date: December 3, 2021
Phase: Phase 2
Study type: Interventional

This study aimed to explore the efficacy and biomarker explanation of IBI-322 Plus Lenvatinib on extensive stage small cell lung cancer who failed from first line PD-(L)1 inhibitors.

NCT ID: NCT05296577 Recruiting - Breast Cancer Clinical Trials

Anlotinib Combination With Vinorelbine in the HER2- Advanced Breast Cancer

Start date: March 22, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of anlotinib combined with vinorelbine in the treatment of HER2- advanced breast cancer.

NCT ID: NCT05296369 Recruiting - Lung Cancer Clinical Trials

Folic Acid Interferes With Radiation Esophagitis

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

This randomized study compared the incidence and severity of radiation esophagitis with folic acid and with conventional symptomatic treatment.