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NCT ID: NCT06413615 Not yet recruiting - Clinical trials for Advanced Solid Tumor

A Study of FDA022-BB05 in Advanced/Metastatic Solid Tumors

Start date: May 13, 2024
Phase: Phase 2
Study type: Interventional

This is an open-label, multicenter, Phase II study to evaluate the efficacy and safety of FDA022-BB05 for the treatment in locally advanced, unresectable, or metastatic patients with selected HER2 overexpressing/expressing solid tumors which are not eligible for curative therapy.

NCT ID: NCT06413303 Recruiting - Health Behavior Clinical Trials

The Effect of Experiential Classroom on Establishing Healthy Behaviors During Pregnancy

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

A multi-center, prospective, randomized controlled clinical trial was conducted to explore the effect of experiential classroom on establishing healthy behaviors during pregnancy.

NCT ID: NCT06413212 Recruiting - Breast Cancer Clinical Trials

Exploratory Study of Precise Therapy for Advanced Tumor Patients With Malignant Hydrothorax or Ascites by Using PTC Drug Sensitivity Testing

Start date: August 4, 2023
Phase:
Study type: Observational

To explore the consistency between result of PTC drug screening tests and actual clinical outcome for patients with advanced malignancy.

NCT ID: NCT06413017 Recruiting - HCC Clinical Trials

Nimotuzumab Combined With ICIs for the Treatment of Advanced Liver Cancer After First Line Treatment Failure

Start date: August 31, 2023
Phase: Phase 2
Study type: Interventional

This is a phase II, open-label, single-arm clinical study of nimotuzumab in combination with immune checkpoint inhibitors in patients with advanced liver cancer who have failed first-line therapy

NCT ID: NCT06412952 Recruiting - Glioma Clinical Trials

68Ga-NOTA-RM26 PET/CT in Glioma Patients

Start date: October 1, 2022
Phase: Early Phase 1
Study type: Interventional

The aim of this study was to investigate the value of 68Ga-NOTA-RM26, an antagonist targeting gastrin-releasing peptide receptor (GRPR) PET tracer, in the diagnosis of high WHO grade glioma and prediction the grade of glioma using positron-emission tomography/computed tomography (PET/CT).

NCT ID: NCT06412783 Completed - Clinical trials for Intracranial Aneurysm

Population-based Investigation of Aneurysm Incidence

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Most intracranial aneurysms are found accidentally in neurovascular imaging. And these inspection methods are limited by the problems of instrument fixation, radiation, time-consuming, contrast agent toxicity and so on. At present, blood test is an ideal alternative method for early diagnosis. Compared with imaging examination, it is economical, general screening and convenient. Blood test is simple to operate, easy to be accepted by patients, and less invasive. Early screening of aneurysms can be performed.

NCT ID: NCT06412575 Completed - Clinical trials for Gastric/Gastroesophageal Junction (g/Gej) Cancer

JNT Versus TNT to Guided OGT-overlap Oesophagojejunostomy

Start date: January 23, 2023
Phase: N/A
Study type: Interventional

Gastric/gastroesophageal junction (G/GEJ) cancer patients who underwent laparoscopic total gastrectomy (LTG) were eligible for this study

NCT ID: NCT06412471 Not yet recruiting - Clinical trials for First-line Advanced NSCLC Patients

A Phase II Study of SSGJ-707 Combination Therapy in Advanced NSCLC Patients

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This study includes two parts, part A is for non-squamous NSCLC and part B is for squamous NSCLC.

NCT ID: NCT06412458 Not yet recruiting - Clinical trials for Recurrent Osteosarcoma

IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma

Start date: June 15, 2024
Phase: Phase 1
Study type: Interventional

The purpose of this study, a single-center, open, single-dose clinical study, was to evaluate the safety, tolerability, and pharmacokinetic profile of IM83 CAR-T cells in the treatment of patients with relapsed or refractory osteosarcoma

NCT ID: NCT06412419 Not yet recruiting - Clinical trials for Esophageal Neoplasms Malignant

Multimodal Endoscopic Image Fusion for Assessing Infiltration in Superficial Esophageal Squamous Cell Carcinoma

Start date: May 15, 2024
Phase:
Study type: Observational

The objective of this project is to pioneer a novel protocol for the adjunctive screening of early-stage esophageal cancer and its precancerous lesions. The anticipated outcomes include simplifying the training process for users, shortening the duration of examinations, and achieving a more precise assessment of the extent of esophageal cancer invasion than what is currently possible with ultrasound technology. This research endeavors to harness the synergy of endoscopic ultrasound (EUS) and Magnifying endoscopy, augmented by the pattern recognition and correlation capabilities of artificial intelligence (AI), to detect early esophageal squamous cell carcinoma and its invasiveness, along with high-grade intraepithelial neoplasia. The overarching goal is to ascertain the potential and significance of this approach in the early detection of esophageal cancer. The project's primary goals are to develop three distinct AI-assisted diagnostic systems: An AI-driven electronic endoscopic diagnosis system designed to autonomously identify lesions. An AI-based EUS diagnostic system capable of automatically delineating the affected areas. A multimodal diagnostic framework that integrates electronic endoscopy with EUS to enhance diagnostic accuracy and efficiency.