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NCT ID: NCT05786781 Recruiting - Hemoptysis Clinical Trials

An Exploratory Study on the Application of Transarterial CT Angiography in the Interventional Treatment of Hemoptysis

Start date: March 2, 2023
Phase: N/A
Study type: Interventional

This is a single-arm, exploratory study to evaluate the value of transarterial CT angiography applying Nexaris Angio-CT in the interventional treatment of hemoptysis

NCT ID: NCT05786586 Recruiting - Myopia Clinical Trials

650nm Low-level Red-light for Myopia Control and Prevention in Children

Start date: March 26, 2023
Phase: N/A
Study type: Interventional

A multicenter randomized controlled trial, evaluating the efficacy and safety of 650nm low-level red-light irradiation for myopia control and prevention in children. Participants included children(aged 6 to 12 years, spherical equivalent error of 0.5D or below) who are already myopic at recruitment, and those who are of Emmetropia or low hyperopia.

NCT ID: NCT05786313 Recruiting - Clinical trials for Cervical Spinal Cord Injury

Study of Individualized, Precise and Standardized Cervical Open-door Surgery for Cervical Spinal Stenosis

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

To evaluate the safety and effectiveness of individualized, precise and standardized open-door posterior cervical surgery through a single-center, exploratory clinical study, so as to provide a more reliable basis for the treatment of cervical spinal stenosis.

NCT ID: NCT05785949 Recruiting - Cartilage Defects Clinical Trials

Chondro-Gide® Bilayer Collagen Membrane in Knee Cartilage Defect Repair

Start date: April 13, 2023
Phase: N/A
Study type: Interventional

A prospective, multicenter, randomized, parallel controlled study evaluating the safety and efficacy of Chondro-Gide® bilayer collagen membrane in knee cartilage defect repair. The objective of this clinical trial is to evaluate the efficacy and safety of Chondro-Gide® bilayer collagen membrane in knee cartilage defect repair

NCT ID: NCT05785793 Recruiting - Clinical trials for Autoimmune Hepatitis

Autoimmune Hepatitis Cohort in China

CAMERA
Start date: February 1, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to describe the clinical features and long-term prognosis in patients diagnosed with autoimmune hepatitis (AIH) in China and assess the effectiveness and safety of AIH treatment options in a real-world setting.

NCT ID: NCT05785741 Recruiting - Clinical trials for Advanced Solid Tumor

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

Start date: April 10, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1310 in subjects with advanced solid tumors.

NCT ID: NCT05785325 Recruiting - Colorectal Cancer Clinical Trials

RC48-ADC Combined With Bevacizumab in HER2-positive Advanced Colorectal Cancer

Start date: August 20, 2023
Phase: Phase 2
Study type: Interventional

A phase II clinical study of RC48-ADC combined with Bevacizumab as late-line treatment in patients with HER2-expressed metastatic colorectal cancer. A total of 30 patients are planned to be enrolled.

NCT ID: NCT05785221 Recruiting - Healthy Clinical Trials

Lifestyle Intervention on Metabolic Homeostasis

Start date: March 2, 2023
Phase: N/A
Study type: Interventional

This is an exploratory controlled before-after study, which involves 112 participants, of whom 28 are with normal weight and 84 are overweight or obese. Twelve weeks of personalized nutritional and lifestyle weight reduction intervention will be conducted in the overweight or obese participants. The objectives of this study are to 1) characterize metabolic homeostasis under resting and exercise conditions, 2) to explore the potential impact factors on metabolic homeostasis, and 3) to investigate whether personalized nutritional and lifestyle weight reduction intervention can improve metabolic health in overweight or obese Chinese individuals and how is it comparable to healthy normal weight Chinese population.

NCT ID: NCT05785195 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

A Mechanistic Study of Inhaled Nitric Oxide in COPD

Start date: March 14, 2023
Phase: N/A
Study type: Interventional

There is a lack of effective treatments for chronic obstructive pulmonary disease (COPD) complicated with pulmonary hypertension. Previous studies have found that inhaled nitric oxide (iNO) can reduce pulmonary artery pressure and improve exercise capacity in COPD with pulmonary hypertension patients. However, the specific mechanism is unclear. The study aims to evaluate pulmonary ventilation/perfusion, pulmonary artery pressure, oxygenation, symptoms and quality of life in COPD with pulmonary hypertension patients after short-term treatment with iNO. Observing a series of pathophysiological changes caused by the treatment of pulmonary hypertension with iNO in COPD, the investigators hope to provide new theoretical basis and research ideas.

NCT ID: NCT05785039 Recruiting - Solid Tumor Clinical Trials

A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Locally Advanced or Metastatic Urinary System Tumors

Start date: April 20, 2023
Phase: Phase 2
Study type: Interventional

Phase IIa/IIb clinical study to evaluate the safety, tolerability, pharmacokinetics and efficacy of BL-B01D1 for injection in patients with multiple solid tumors such as locally advanced or metastatic urinary system tumors.