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Clinical Trial Summary

There is a lack of effective treatments for chronic obstructive pulmonary disease (COPD) complicated with pulmonary hypertension. Previous studies have found that inhaled nitric oxide (iNO) can reduce pulmonary artery pressure and improve exercise capacity in COPD with pulmonary hypertension patients. However, the specific mechanism is unclear. The study aims to evaluate pulmonary ventilation/perfusion, pulmonary artery pressure, oxygenation, symptoms and quality of life in COPD with pulmonary hypertension patients after short-term treatment with iNO. Observing a series of pathophysiological changes caused by the treatment of pulmonary hypertension with iNO in COPD, the investigators hope to provide new theoretical basis and research ideas.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05785195
Study type Interventional
Source China-Japan Friendship Hospital
Contact Ruoxi He
Phone +8618874167666
Email heruoxi1985@yeah.net
Status Recruiting
Phase N/A
Start date March 14, 2023
Completion date March 31, 2024

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