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NCT ID: NCT06039163 Completed - COVID-19 Clinical Trials

A Study to Assess the Safety, Tolerability and Preliminary Efficacy of HH-120 for the Treatment of COVID-19

Start date: April 16, 2022
Phase: Phase 1
Study type: Interventional

This is a randomized, double-blind, placebo-controlled Phase 1 study in participants over the age of 18 years with mild to moderate COVID-19. This study aims to assess the safety, tolerability and preliminary antiviral effect of HH-120. This study includes dose escalation phase and dose expansion phase.

NCT ID: NCT06039059 Completed - Clinical trials for Coronary Artery Disease

Influence of Risk Factors on ISR and Nonintervened Lesions

Start date: January 1, 2020
Phase:
Study type: Observational

This study enrolled patients who used to received PCI therapy with nonintervened coronary lesions. Baseline characteristics and laboratory testing were collected to find out the risk factor difference between ISR and nonintervened coronary lesions.

NCT ID: NCT06038994 Recruiting - Clinical trials for Myocardial Infarction, Acute

Prognostic Value of Surem TRAF3IP2 Level in Patients With Acute Myocardial Infarction

Start date: September 1, 2023
Phase:
Study type: Observational

To evaluate the prognostic value of surem TRAF3IP2 levels in patients with acute myocardial infarction

NCT ID: NCT06038916 Recruiting - Clinical trials for Acute Respiratory Distress Syndrome

To Evaluate The Safety and Initial Efficacy of STSA-1002 Injection in Patients With Acute Respiratory Distress Syndrome

Start date: December 9, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the safety and initial efficacy of STSA-1002 injection in patients with acute respiratory distress syndrome.

NCT ID: NCT06038552 Completed - Liver Metastases Clinical Trials

The Long-term Efficacy of Imatinib With Hepatic Resection or Other Local Treatment for GIST Liver Metastases

Start date: January 1, 2002
Phase:
Study type: Observational

The goal of this observational study is to evaluate the overall survival benefits of local treatment combined with imatinib(IM) and IM alone in patients suffering from GIST liver metastases. The main question it aims to answer is: • Whether IM combined with hepatic resection (HR) or other local treatments such as radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) has better long-term survival benefits compared to IM monotherapy. Patients are divided into different treatment groups: - IM group - IM combined with HR group - IM combined with RFA or TACE group Researchers will compare the IM + HR group and IM + RFA/TACE group with the IM group to see if it has a better Overall survival (OS).

NCT ID: NCT06038461 Not yet recruiting - Clinical trials for Neuroendocrine Tumors

An Open, Single-center Clinical Study of Surufatinib Combined With Temozolomide and S-1 in the First-line Treatment of Advanced Neuroendocrine Tumors

Start date: September 15, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is a prospective, open, single-center study evaluating the efficacy and safety of surufatinib Combined With Temozolomide and S-1 as the first-line treatment of advanced neuroendocrine tumors

NCT ID: NCT06038396 Recruiting - Clinical trials for Advanced Solid Tumor

A Study of RC118 Plus Toripalimab in Patients With Locally Advanced Unresectable or Metastatic Solid Tumors

Start date: August 3, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

In Phase I, This study will explore the tolerability and safety of RC118 in combination with toripalimab for treatment of patients with locally advanced unresectable or metastatic malignant solid tumors with positive Claudin 18.2 expression, and determine the maximum tolerated dose (MTD) and the recommended dose in phase II clinical trials (RP2D); In Phase IIa, to explore the clinical effectiveness and safety of long-term use of RC118 in combination with toripalimab at RP2D doses for patients with different tumor types.

NCT ID: NCT06038123 Recruiting - Heart Failure Clinical Trials

China 3T MRI Study

Start date: November 28, 2023
Phase: N/A
Study type: Interventional

The purpose of the China CIED 3.0T MRI Performance Study is to confirm safety of SureScan CIED in the clinical 3.0T MRI environment when subjects receive MRI scans. ll subjects will have required follow-up visits at baseline, MRI visit, 1-month post-MRI. The MRI scans will occur at the MRI visit. The MRI scan region will be determined by investigator according to the subject's clinical condition.

NCT ID: NCT06038058 Not yet recruiting - Clinical trials for Advanced Malignancies

A Phase I Study of BRY812 for Injection Alone in Subjects With Advanced Malignancies

Start date: October 2023
Phase: Phase 1
Study type: Interventional

This is a Phase I, multicenter, open-label, single-arm and first-in-human clinical study of BRY812 for injection. The study objectives are to evaluate the safety, tolerability, pharmacokinetic profile, anti-tumor activity and immunogenicity of BRY812 for injection in patients with advanced malignancies. Patients will receive treatment every 3 weeks until intolerable toxicity, disease progression, pregnancy, withdrawal of informed consent, death, study discontinuation, or withdrawal from the study.

NCT ID: NCT06038006 Recruiting - Clinical trials for Sleep Breathing Disorders

A Clinical Trial Evaluating the Effectiveness and Safety of a mmWave Radar Based Sleep Respiratory Monitoring System

Start date: July 13, 2023
Phase: N/A
Study type: Interventional

This study compares the diagnostic capability of a millimeter-wave radar-based Sleep Respiratory Monitoring System to the gold standard polysomnography.