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NCT ID: NCT06102291 Recruiting - Clinical trials for Non-specific Low Back Pain

Acupoint Application With Yanqing Zhitong Ointment for Chronic Non-specific Low Back Pain

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

This is a non-inferiority randomized controlled trial, recruiting 150 patients with chronic non-specific low back pain. The patients will be randomly assigned either to Yanqing Zhitong Ointment acupoint application group (Treatment Group) or the acupuncture group (Control Group) in a 1:1 ratio.

NCT ID: NCT06102278 Completed - Clinical trials for Peritoneal Metastasis

ML Models for Predicting Postoperative Peritoneal Metastasis After Hepatocellular Carcinoma Rupture

Start date: January 1, 2020
Phase:
Study type: Observational

This study aimed to address the issue of peritoneal metastasis (PM) following the rupture of hepatocellular carcinoma (HCC) and its adverse impact on patient prognosis. Clinical data from 522 patients with ruptured HCC who underwent surgery at seven different medical centers were collected and analyzed. Machine learning models were employed for analysis and prediction.

NCT ID: NCT06102226 Recruiting - Clinical trials for Coronary Artery Disease

Deep Learning Algorithm for Detecting Obstructive Coronary Artery Disease Using Fundus Photographs

Start date: July 1, 2021
Phase:
Study type: Observational

Artificial Intelligence, trained through model learning, can quickly perform medical image recognition and is widely used in early disease screening and assisted diagnosis. With the continuous optimization of deep learning, the application of AI has helped to discover some previously unknown associations with other systemic diseases. Artificial intelligence based on retinal fundus images can be used to detect anemia, hepatobiliary diseases, and chronic kidney disease, and to predict other systemic biomarkers. The above studies provide a theoretical basis for the application of artificial intelligence technology based on retinal fundus images to the diagnosis and prediction of cardiovascular diseases. At present, there is still a lack of accurate, rapid, and easy-to-use diagnostic and therapeutic tools for predictive modeling of coronary heart disease risk and early screening tools in China and the world. Fundus image is gradually used as a tool for extensive screening of diseases due to its special connection with blood vessels throughout the body, as well as easy access, cheap and efficient. It is of great scientific and social significance to develop and validate a model for identification and prediction of coronary heart disease and its risk factors based on fundus images using AI deep learning algorithms, and to explore the value of AI fundus images in assisting coronary heart disease diagnosis and screening for a wide range of applications.

NCT ID: NCT06102187 Recruiting - Chronic Disease Clinical Trials

Cohort Study in Fujian Province

Start date: January 1, 2017
Phase:
Study type: Observational

In this study, Chinese residents aged 35 to 75 years old were recruited from Fujian Province. Physical examination, questionnaire survey and biological sample collection were performed at baseline, and at least 4 years of follow-up were conducted. Information on newly discovered cardiovascular metabolic illnesses and comorbidities was collected during follow-up, and repeated surveys similar to baseline were conducted. To explore the relationship between environment, diet and lifestyle and the risk of cardiovascular metabolic diseases and concomitant disorders.

NCT ID: NCT06102161 Not yet recruiting - Lung Cancer Clinical Trials

Wedge Resection for Ground-glass Opacity-featured Lung Cancer (ECTOP-1020)

Start date: November 2023
Phase: Phase 3
Study type: Interventional

This is a clinical trial from the Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1020. The goal of this clinical trial is to confirm the therapeutic effect of Wedge resection for ground-glass opacity-featured lung cancer with a size less than 2cm and a consolidation-to-tumor ratio between 0.25 to 0.5.

NCT ID: NCT06102018 Recruiting - Clinical trials for Breast Neoplasm Female

Diagnostic Biomarkers Exploration of Breast Cancer From Serum and Urine

Start date: June 22, 2022
Phase:
Study type: Observational

The goal of this observational study is to find the diagnostic biomarkers in serum and urine from early breast cancer patients. The main questions it aims to answer are: - compare the different biomarkers in serum and urine from breast cancer patients, benign lesions and healthy population. - construct the best diagnostic model by machine learning to distinguish breast cancer and non-breast cancer patients. Participants, including breast and non-breast cancer patients will be asked to provides blood and urine during their diagnosis and treatment process without changing the original treatment. When necessary, specimens will be collected during the surgery,without affecting pathological diagnosis.

NCT ID: NCT06102005 Recruiting - Asthma Clinical Trials

Dose Ranging Study of Lunsekimig Compared With Placebo-control in Adult Participants With Moderate-to-severe Asthma

AIRCULES
Start date: October 16, 2023
Phase: Phase 2
Study type: Interventional

This is a Phase 2b, global, multicenter, randomized, double-blind, placebo-controlled, parallel group, dose ranging study to assess the efficacy, safety, and tolerability of add-on therapy with SC lunsekimig in adult participants aged 18 to 80 years, (inclusive) with moderate-to-severe asthma.

NCT ID: NCT06101966 Not yet recruiting - Cervical Cancer Clinical Trials

A Predictive Model for Early Metastasis in Cervical Cancer Patients After Radiotherapy

Start date: December 1, 2023
Phase:
Study type: Observational

This study aims to help to screen out appropriate cases for consolidation therapy and more intensive follow up.

NCT ID: NCT06101940 Enrolling by invitation - Clinical trials for Myotonic Dystrophy 1

A Multicenter Phenotype-Genotype Analysis of DM1 Patients in China

Start date: August 1, 2021
Phase:
Study type: Observational

Myotonic dystrophy 1 (DM1) is an autosomal, dominantly inherited neuromuscular disorder characterized by skeletal muscle weakness, myotonia, cardiac conduction abnormalities, cataracts, and other abnormalities. This disease results from an expansion of a cytosine-thymine-guanine (CTG) trinucleotide repeat in the 3'-untranslated region of the dystrophia myotonica protein kinase (DMPK) gene on chromosome 19. Currently, there is limited phenotype and genotype data available for DM1 patients with Chinese Han ethnicity. Therefore, this study aims to fill this gap and provide complementary data.

NCT ID: NCT06101888 Recruiting - Clinical trials for Aortic Regurgitation

Safety and Effectiveness of TaurusTrio™ Heart Valve System in Patients With Severe Aortic Regurgitation (AR)

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

To evaluate the safety and effectiveness of the TaurusTrio™ Heart Valve System in a patient population with symptomatic severe AR requiring replacement/repair of their native aortic valve that are at high risk for open surgical aortic valve replacement/repair (SAVR).