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NCT ID: NCT06171061 Recruiting - Clinical trials for Chronic Coronary Syndrome

Yangxinshi Tablet Intervention for Exercise Capacity in Patients With Chronic Coronary Syndrome

Start date: December 18, 2023
Phase: Phase 4
Study type: Interventional

This study is a prospective, multicentre, randomized, open-label, blinded-endpoint clinical trial to evaluate the efficacy and safety of Yangxinshi tablets in the treatment of patients with chronic coronary syndrome (CCS).

NCT ID: NCT06171048 Not yet recruiting - Healthy Clinical Trials

Study Evaluating the Pharmacokinetics of CM310 in Healthy Subjects

Start date: April 30, 2024
Phase: Phase 1
Study type: Interventional

This is a single-center, randomized, open-label study to evaluate the pharmacokinetics of CM310 in healthy subjects.

NCT ID: NCT06170996 Recruiting - Clinical trials for Attention Deficit Hyperactivity Disorder (ADHD)

Internet-Assisted Behavioral Parent Training Intervention for Children With Attention Deficit Hyperactivity Disorder

Start date: September 12, 2023
Phase: N/A
Study type: Interventional

This study aims to investigate the effectiveness of an Internet-Assisted behavioral parent training intervention on children's ADHD symptoms and children's and parents' mental health status.

NCT ID: NCT06170840 Recruiting - Psoriasis Clinical Trials

A Study of QY101 Ointment in Subjects With Plaque Psoriasis

Start date: May 17, 2023
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to evaluate the effectiveness of QY101 ointment in adult patients with plaque psoriasis (2-20% BSA).

NCT ID: NCT06170788 Recruiting - Clinical trials for Non-small Cell Lung Cancer (NSCLC)

Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

Start date: December 15, 2023
Phase: Phase 3
Study type: Interventional

The primary objective of the study is to compare sacituzumab tirumotecan combined with pembrolizumab to pembrolizumab alone with respect to overall survival (OS). The primary hypothesis is that the combination of sacituzumab tirumotecan and pembrolizumab is superior to pembrolizumab alone with respect to OS. All participants who have completed the first course of pembrolizumab may be eligible for up to an additional 9 cycles of pembrolizumab monotherapy if there is blinded independent central review (BICR)-verified progressive disease by Response Evaluation Criteria In Solid Tumors version 1.1 (RECIST 1.1) after initial treatment.

NCT ID: NCT06170749 Recruiting - Anemia Clinical Trials

Prediction Model for Anemia After Bariatric Surgery

Start date: September 1, 2017
Phase:
Study type: Observational [Patient Registry]

To develop and validate a prediction model for estimating the short and long-term risk of anemia after bariatric surgery.

NCT ID: NCT06170710 Recruiting - Clinical trials for Head and Neck Squamous Cell Carcinoma

Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC

Start date: December 1, 2023
Phase: Phase 2
Study type: Interventional

This trial aims to evaluate whether the addition of anti-PD-1 antibody to adjuvant postoperative chemoradiotherapy could improve disease free survival in patients with high-risk locally advanced head and neck squamous cell carcinoma (HNSCC).

NCT ID: NCT06170697 Recruiting - Clinical trials for Head and Neck Squamous Cell Carcinoma

Advanced First-line Treatment of Short-term Postoperative Progression of Head and Neck Squamous Cell Carcinoma

Start date: March 1, 2023
Phase: Phase 2
Study type: Interventional

Every year, about 6% of patients with malignant tumors are diagnosed as head and neck cancer. There are about 650000 new cases and 350000 deaths. A considerable number of patients have simple local recurrence in the short term after operation suggesting that the biological behavior of this kind of tumor is relatively more invasive and the overall prognosis is poor. This project intends to study the efficacy and safety of camrelizumab combined with concurrent chemoradiotherapy for short-term postoperative progression of head and neck squamous cell carcinoma.

NCT ID: NCT06170489 Recruiting - Hodgkin Lymphoma Clinical Trials

A Phase III Clinical Study Comparing JS004 Plus Toripalimab With Investigator-Selected Chemotherapy in Patients With PD-(L)1monoclonal Antibody Refractory Classic Hodgkin Lymphoma (cHL)

Start date: December 19, 2023
Phase: Phase 3
Study type: Interventional

The study is being conducted to compare JS004 plus Toripalimab with Investigator-Selected Chemotherapy in Patients with PD-(L)1 monoclonal antibody refractory Classic Hodgkin Lymphoma (cHL)

NCT ID: NCT06170476 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in PONV

Start date: November 10, 2023
Phase: N/A
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled Dose-Finding study. About 200 subjects undergoing elective laparoscopic abdominal or gynecological surgery are planned to be enrolled and randomized into four groups by a ratio of 1:1:1:1.