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NCT ID: NCT06207344 Recruiting - Clinical trials for Postoperative Complications

The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy

Start date: October 21, 2023
Phase: N/A
Study type: Interventional

In one-lung ventilation surgery, compared with dexmedetomidine combined with propofol, dexmedetomidine combined with desflurane may be beneficial to accelerate patients' recovery and reduce postoperative pulmonary complications and does not increase the incidences of delirium and postoperative nausea and vomiting.

NCT ID: NCT06207331 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Effects of Atomized Dexmedetomidine on Lung Function in Patients With Chronic Obstructive Pulmonary Disease

Start date: October 28, 2023
Phase: N/A
Study type: Interventional

Studies have shown that intravenous infusion and nebulized dexmedetomidine can improve lung function in mechanically ventilated patients, including those with preoperative COPD, exerting lung protection. However, these studies are based on mechanical ventilation patients under general anesthesia, and more intuitive research is needed on whether dexmedetomidine can also exercise pulmonary precaution in awake patients. Pulmonary function monitoring is the most direct way to evaluate changes in lung function in awake patients. Portable pulmonary function machines can assess lung function in a variety of settings. In addition, compared with intravenous administration, nebulized inhalation administration directly acts on the mucosa of the respiratory tract, does not involve invasive operations, and has higher safety and comfort. Therefore, this study intends to use portable pulmonary function instruments and non-invasive ambulatory respiratory monitors to evaluate the effect of nebulized dexmedetomidine on lung function in COPD patients to guide the perioperative management of COPD patients.

NCT ID: NCT06207279 Recruiting - Healthy Clinical Trials

Preliminary Study on the Development and Reliability and Validity of Attention Rating Scale

Start date: September 28, 2023
Phase:
Study type: Observational

This study, based on preliminary experimental results, literature review, and expert consultations, developed the Attentional Rating Scale (ARS). The aim was to rapidly assess participants' attention and potential influencing factors. The research focused on the scale's reliability and validity among healthy adults. Additionally, the Attention Network Test (ANT) served as the gold standard for evaluating attention. The study attempted to identify correlations between various dimensions of attention and the three attentional networks.

NCT ID: NCT06206902 Recruiting - Clinical trials for Non-Hodgkin's Lymphoma

F01 in the Treatment of Relapsed/Refractory Non-hodgkin's Lymphoma

Start date: April 2024
Phase: Phase 1
Study type: Interventional

This is a multicenter, open, Phase I clinical study to evaluate the safety and tolerability of F01 in subjects with relapsed/refractory non-Hodgkin lymphoma, and to determine MTD and/or RD.

NCT ID: NCT06206733 Recruiting - Clinical trials for Gastric Adenocarcinoma

ASKB589 in Combination With CAPOX and PD-1 Inhibitor in Patients With Advanced or Metastatic GC/GEJ Adenocarcinoma

Start date: January 25, 2024
Phase: Phase 3
Study type: Interventional

This study is a multicenter, randomized, double-blind, standard-of-care controlled phase III clinical study conducted in China. The purpose of this study is to evaluate the efficacy of ASKB589 plus CAPOX and PD-1 inhibitor compared with placebo plus CAPOX and PD-1 inhibitor (as first-line treatment) as measured by Progression Free Survival (PFS).

NCT ID: NCT06206720 Recruiting - Clinical trials for Respiratory Syncytial Virus Infection

A Study of Deuremidevir Hydrobromide for Suspension in Chinese Infants Hospitalized With RSV

Start date: January 31, 2024
Phase: Phase 2
Study type: Interventional

To evaluate the safety, efficacy, pharmacokinetic (PK) characteristics and antiviral activity of different doses of Deuterium Hydrobromide for suspension in the treatment of respiratory syncytial virus infection in infants.

NCT ID: NCT06206681 Recruiting - Keratosis Clinical Trials

Efficacy and Safety of Ultrapulse Carbon Dioxide Laser Treatment in Eyelid Tumors

Start date: November 1, 2022
Phase:
Study type: Observational

This study aims to assess the long-term efficacy and safety of ultrapulse carbon dioxide (CO₂) laser excision in the treatment of eyelid tumors, including xanthelasma, pigmented nevi, keratoses, and so on.

NCT ID: NCT06206642 Completed - Malignant Neoplasm Clinical Trials

Comparing 18F-FAPI-04 and 18F-FDG PET/CT in Cancer Detection

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Evaluating fluoro-18-fibroblast activation protein inhibitor-04 positron emission computed tomography's diagnostic efficacy for primary malignancies versus 18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose.

NCT ID: NCT06206590 Recruiting - Neonatal Disease Clinical Trials

Analysis of Differential Proteins and Maternal Influencing Factors of Septic Shock in Neonates

Start date: November 1, 2023
Phase:
Study type: Observational

1. Explore 32 weeks of premature infants or maternal pregnancy infection of newborn septic shock maternal influence factors. 2. Through maternal blood samples before delivery and labor cord blood sample screening and septic shock related proteomics analysis, explore the relationship between the difference protein and septic shock and prognosis, and explore the pathway mechanism, in order to prevent and reduce the occurrence of septic shock in premature infants

NCT ID: NCT06206538 Withdrawn - Parkinson Disease Clinical Trials

Efficacy of Stellate Ganglion Block in Patients With Parkinson's Disease

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

The goal of this or clinical trial is to explore efficacy of stellate ganglion block on dysphagia and activities of daily living in patients with Parkinson's disease. The main question it aims to answer are: • Can stellate ganglion block improve the dysphagia and activities of daily living in patients with Parkinson's disease. Participants will be divided into the the control group and observation group evenly. All the patients were provided with routine therapy, while the patients in the observation group were given stellate ganglion block. The swallowing function, and activities of daily living of the two groups of patients before and after treatment were evaluated.