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NCT ID: NCT06053021 Recruiting - Clinical trials for Acute Ischemic Stroke

Antiplatelet Therapy for AIS Patients With Thrombocytopenia

PERSIST
Start date: September 15, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the safety and effectiveness of antiplatelet therapy in acute ischemic stroke (AIS) patients with thrombocytopenia. Participants will be prescribed antiplatelet agents and followed up for 3 months.

NCT ID: NCT06052813 Recruiting - AML, Adult Clinical Trials

A Study of BN104 in the Treatment of Acute Leukemia

Start date: September 16, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The Phase I/II trial is to learn the safety, pharmacokinetics, and preliminary efficacy of BN104 taken once daily or twice daily in patients with acute lymphocytic leukemia or acute myeloblastic leukemia.

NCT ID: NCT06052098 Recruiting - Clinical trials for Stage IA Lung Cancer

Transbronchial vs Transthoracic Ablation for Early-stage Peripheral Lung Cancer

Start date: October 11, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the efficacy and safety of RFA through a transthoracic or transbronchial approach in the treatment of early-stage peripheral lung cancer.

NCT ID: NCT06052033 Recruiting - HPV Infection Clinical Trials

Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection

Start date: September 11, 2023
Phase: N/A
Study type: Interventional

Non-RCT clinical trial comparing 5-ALA photodynamic therapy and CO2 laser for persistent high-risk HPV-related low-grade cervical lesions.

NCT ID: NCT06052020 Recruiting - Stroke Clinical Trials

Extra Alirocumab in Addition to Statin Therapy in Symptomatic IntraCranial Atherosclerotic Stenosis ----a Pilot Study

EAST-sICAS
Start date: September 15, 2023
Phase:
Study type: Observational

The primary goal of the trial is to investigate whether the lipid lowering strategy using Alirocumab plus statin could cause more changes from baseline in intracranial atherosclerotic plaque and hemodynamic features during 6 months of follow-up, in patients with recent stroke/transient ischemic attack (TIA) caused by intracranial artery stenosis.

NCT ID: NCT06051851 Recruiting - Clinical trials for Pancreatic Adenocarcinoma Metastatic

Penpulimab Combined With Anlotinib and Nab-paclitaxel Plus Gemcitabine as First-line Treatment for Advanced Metastatic Pancreatic Cancer

RCT-PAAG
Start date: July 1, 2023
Phase: Phase 2
Study type: Interventional

This is a multi-center, open-label, randomized controlled Phase II clinical study to observe and evaluate the efficacy and safety of Penpulimab combined with Anlotinib and Nab-paclitaxel plus Gemcitabine (PAAG ) versus AG first-line treatment in patients with metastatic pancreatic cancer.

NCT ID: NCT06051513 Recruiting - Clinical trials for Carbapenem-Resistant Enterobacteriaceae Infection

Efficacy and Safety of Colistimethate Sodium for Injection in The Treatment of Carbapenem-Resistant Enterobacteriaceae Infection

Start date: September 21, 2023
Phase: N/A
Study type: Interventional

Colistin can be used to treat the infection caused by carbapenem-resistant enterobacteriaceae(CRE). In China, patients diagnosed with Hospital-acquired-pneumonia (HAP)or bloodstream infection caused by CRE are recruited, and randomly assigned to two groups, and in one group the patients accept treatment with colistin, however in another group, the patients accept treatment without colistin. The efficacy and safety of the treatment between the two groups are compared.

NCT ID: NCT06051409 Recruiting - Ph+ ALL Clinical Trials

A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ALL.

Start date: August 31, 2023
Phase: Phase 3
Study type: Interventional

A global multicenter, open-label, randomized and registrational Phase 3 study to evaluate efficacy and safety of Olverembatinib combined with chemotherapy versus Imatinib combined with chemotherapy in subjects with newly diagnosed Ph+ALL.

NCT ID: NCT06051266 Recruiting - Edentulous Jaw Clinical Trials

Accuracy of Dynamic Navigation and Static Template in Completely Edentulous Patients

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The study was a prospective, multicentre, randomized parallel controlled clinical trial. Randomisation was conducted by central randomisation, with random allocation codes generated by the main central computer. Enrollment was conducted by competition between different centres. In this study, the coronal, apical and angular deviations (mean, standard deviation, median, quartiles, minimum, maximum, 95% confidence interval) of the static template and dynamic navigation group guided implant placement were calculated. The data is proposed to be analysed using a mixed linear effects model.

NCT ID: NCT06050980 Recruiting - NSCLC Clinical Trials

Phase I Study of HSK40118 in NSCLC Patients With EGFR Mutation

Start date: March 27, 2023
Phase: Phase 1
Study type: Interventional

This is a phase I, open-label, dose-escalation and expansion study to evaluate the safety, tolerability, PK and PD of HSK40118 when given orally in patients with active EGFR mutation locally advanced or metastatic non-small cell lung cancer (NSCLC). The study will contain two phase: Phase Ia is dose escalation phase and Phase Ib is dose expansion phase.