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NCT ID: NCT06255379 Not yet recruiting - Rectal Cancer Clinical Trials

Study of Fruquintinib Combined With Tegafur Gimeracil Oteracil in Patients With Metastatic Colorectal Cancer

Start date: May 6, 2024
Phase: Phase 2
Study type: Interventional

This is an Open, Single-arm, Multicenter, Prospective Phase II Study of Fuquinitinib Combined With Tegafur Gimeracil Oteracil in the Third-line Treatment of Patients With Advanced Metastatic CRC

NCT ID: NCT06255262 Not yet recruiting - Clinical trials for Biliary Tract Cancer

Durvalumab Combined With Surufatinib as Maintenance Therapy in Patients With Advanced Biliary Tract Cancer

Start date: February 15, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

A Real-World Study of Durvalumab combined with Surufatinib as maintenance therapy in patients with advanced biliary tract cancer whose disease did not progress after completion of first-line Durvalumab combined with Gemcitabine+cisplatin treatment.

NCT ID: NCT06255223 Recruiting - Clinical trials for Renal Cell Carcinoma

A Study of Multimodal Radiotherapy for Renal Cell Carcinoma Progressed After Prior Immunotherapy

Start date: December 15, 2023
Phase: Phase 2
Study type: Interventional

The objective of this single-center clinical study was to evaluate the disease control rate(DCR) and safety of multimodal radiotherapy in the treatment of patients with renal cell carcinoma (RCC) progressed after prior immunotherapy.

NCT ID: NCT06255210 Recruiting - Clinical trials for Olfactory Neuroblastoma

Efficacy and Safety of Induction Chemotherapy for Olfactory Neuroblastoma (ESICON)

ESICON
Start date: March 1, 2024
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to learn about the induction chemotherapy efficacy in olfactory neuroblastoma. The main question it aims to answer is: wether olfactory neuroblastoma patients with different pathology subtypes apply to different induction chemotherapy schemes. Participants will be treated with different chemotherapy schemes, to evaluate the tumor remission rate and long term survival.

NCT ID: NCT06255197 Recruiting - Lung Cancer Clinical Trials

Characteristics, Treatment Patterns and Outcomes for Patients With Surgically Resected Lung Cancers

Start date: November 4, 2019
Phase:
Study type: Observational

This study is a multi-center, observational, real-world study for patients with resected lung cancers in China. With the help of a properly designed data processing algorithm and extensively performed data quality assurance, this study aims to harness the potential of real-world big data to (1) describe characteristics and treatment patterns and their evolving trends; (2) discover features associated with overall survival; and (3) address recently-emerging clinical questions.

NCT ID: NCT06254859 Recruiting - Thyroid Cancer Clinical Trials

Intraoperative Neuromuscular Monitoring and Its Impact on Pre- and Postoperative Acoustic Outcomes in Thyroid Surgery

Start date: March 1, 2024
Phase:
Study type: Observational

This study examines the impact of intraoperative recurrent laryngeal nerve monitoring signal changes on the postoperative voice quality of thyroid surgery patients. By analyzing extensive surgical data and postoperative voice recordings, the investigation seeks to identify patterns in the variations of these signals and their correlation with voice quality outcomes. The goal is to enhance clinical understanding and surgical practices, allowing for more precise assessments of nerve function, informed surgical interventions, and improved postoperative patient well-being.

NCT ID: NCT06254742 Not yet recruiting - Clinical trials for Patients With Nonmyeloid Malignancies Receiving Antineoplastic Therapy Based on Chemotherapy Regimens at Moderate to High Febrile Neutropenia (FN) Risk

A Trial of HHPG-19K Injection and Auto-HHPG-19K Injection in Prevention of Chemotherapy-related Moderate to Severe Neutropenia of Patients With Nonmyeloid Malignancies

Start date: February 2024
Phase: Phase 3
Study type: Interventional

The study is being conducted to evaluate the preference, and safety of HHPG-19K Injection and Auto-HHPG-19K Injection in Prevention of chemotherapy-related moderate to severe neutropenia of Patients with nonmyeloid malignancies.

NCT ID: NCT06254716 Recruiting - Quality of Life Clinical Trials

A Study on the Prognosis of Two Different Surgery Methods in Patients With Rectal Endometriosis

Start date: January 1, 2024
Phase:
Study type: Observational

This retrospective study aims to compare the surgical and pregnancy outcomes of disc and segmental resection for rectal DIE through a single-center retrospective analysis, to summarize clinical experience, and to explore the possible factor of the differences. The results would provide preliminary clinical basis for the treatment and selection of surgical methods for patients with rectal DIE, and also provide a research basis for the prospective clinical studies.

NCT ID: NCT06254690 Recruiting - Breast Cancer Clinical Trials

The Dosing Regimen of Pyrotinib in HER2-positive Advanced First-line Breast Cancer: a Phase II Clinical Study

Start date: January 1, 2024
Phase: Phase 2
Study type: Interventional

Evaluate the safety and efficacy of Pyrotinib in the transition from low-dose to normal-dose regimen for HER2-positive advanced first-line breast cancer

NCT ID: NCT06254599 Not yet recruiting - Clinical trials for Non-small Cell Lung Cancer

A Study Of SY-3505 Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC

Start date: May 1, 2024
Phase: Phase 3
Study type: Interventional

A phase 3 study to evaluate the efficacy and safety of SY-3505 vs. crizotinib in patients with ALK-positive non-small cell lung cancer who had not received prior systemic therapy.