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NCT ID: NCT05600699 Completed - Clinical trials for Atrioventricular Block

Long-term Efficacy and Safety Research of Left Bundle Branch Pacing

Start date: April 1, 2018
Phase:
Study type: Observational [Patient Registry]

Patients with successful left bundle branch pacing in our center were included in this study from April 2018 to December 2019. Baseline data was collected, and pacing parameters, ECG and echocardiographic results were analyzed during 3 years follow-up. According to whether or not a potential was recorded and the specific potential characteristics at implantation, the patients were divided into 3 groups: left bundle branch potential group; Purkinje potential group; and no-potential group. During the 3 years follow-up, the investigators collected the ECG、UCG and pacemaker parameters to analyze.

NCT ID: NCT05600504 Completed - Predictive Model Clinical Trials

Development and Validation of a Prediction Model for Depression and Anxiety in Perioperative Elderly Adults

Start date: April 1, 2020
Phase:
Study type: Observational

Anxiety and depression in later life are highly prevalent, often appear as comorbid disorders, and have many adverse consequences for both the individual and society. Given the disease burden, the large influx of new cases, and the economic costs, efforts should be made to prevent the onset of anxiety and depression in later life. Preventive interventions are likely to become more cost effective when they are targeted at elderly who have been exposed to risk factors known to be predictive of the onset of anxiety and/or depression. As the population aging is speeding up, senile diseases have become a significant and severe public health problem, influencing national health. More than 20 million elderly patients undergo surgery each year in China, accounting for a quarter of the population who undergo surgery. Therefore, it is necessary to construct a predictive model of anxiety and depression in perioperative elderly hospitalized patients

NCT ID: NCT05600335 Completed - Clinical trials for Esophageal Cancer Patients

Short-term Outcomes of ERAS Protocol in RAME for Esophageal Cancer

Start date: January 1, 2019
Phase:
Study type: Observational

This single-center, retrospective cohort study aimed to evaluate the short-term outcomes of enhanced recovery after surgery (ERAS) protocol in perioperative robotic-assisted McKeown esophagectomy (RAME) among esophageal cancer patients.

NCT ID: NCT05600322 Completed - Bladder Cancer Clinical Trials

Comparative Study of Hexvix Blue Light Cystoscopy and White Light Cystoscopy in the Detection of Bladder Cancer

Start date: November 3, 2022
Phase: Phase 3
Study type: Interventional

A study to compare Hexvix Blue light cstoscopy with standard White light cystoscopy in the detection of bladder cancer.

NCT ID: NCT05598658 Completed - Clinical trials for Remote Ischemic Conditioning

Effect of Remote Ischemic Conditioning on Cerebral Hemodynamics in Patients After Intravenous Thrombolysis (RICCH-IVT)

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of remote ischemic conditioning on cerebral hemodynamics in patients after intravenous thrombolysis

NCT ID: NCT05598606 Completed - Denosumab Allergy Clinical Trials

Denosumab vs Zoledronate After Vertebroplasty

Start date: January 12, 2021
Phase: Phase 4
Study type: Interventional

Osteoporotic vertebral compression fracture (OVCF) patients had a proportion of secondary fractures after percutaneous vertebroplasty (PVP). Denosumab and zoledronate acid is both effective to prevent bone loss for OVCF postmenopausal women. However, trial evidence comparing effect of denosumab vs zoledronate after PVP was unknown. The study aims to assess the efficiency of denosumab vs zoledronate for OVCF patients bone mineral density (BMD), bone turnover markers (BTMs), secondary fracture and adverse events after PVP.

NCT ID: NCT05598177 Completed - Clinical trials for Ischemia-Reperfusion Injury

Effect of Dexmedetomidine Preconditioning on Myocardial Ischemia-reperfusion Injury in Patients Undergoing Open Heart Surgery With Cardiopulmonary Bypass

Start date: September 1, 2022
Phase: Phase 4
Study type: Interventional

About 200000 cardiac operations are performed in China every year. Cardiopulmonary bypass is the basic strategy of open-heart surgery, which may lead to myocardial ischemia-reperfusion injury and low cardiac output syndrome. It will inevitably affect the patient's postoperative recovery. A number of studies have shown that dexmedetomidine, as an auxiliary sedative, has the effects of inhibiting stress response, antiarrhythmia and cardiac protection.Dexmedetomidine has been widely used in anesthesia in cardiac surgery. However, at present, few clinical studies pay attention to its mechanism. In this study, dexmedetomidine will be used in cardiac surgery with cardiopulmonary bypass to explore the mechanism of cardiac ischemia-reperfusion injury and the protective effect of dexmedetomidine.

NCT ID: NCT05598086 Completed - Fracture Clinical Trials

Anti-fibrinolytic and Anti-inflammatory Effects of Local Infiltration of Tranexamic Acid in Patients With Calcaneal Fractures

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

Background. Consensus is lacking regarding the use of tranexamic acid (TXA) in calcaneal fracture surgery. This study aims to investigate the hypothesis that local infiltration of TXA in the post-operation would maintain hemoglobin (Hb) level, reduce incision drainage volume and risk of infection in patients with displaced intra-articular calcaneal fractures. Methods. A total of 120 patients with displaced intra-articular calcaneal fractures who received extensible lateral L-shaped approach were included in this trial and equally randomized to receive one single dose of 1g TXA or 1g normal saline after closing incision. The demographic data and fracture characteristics, intra-operative indicators, laboratory tests and Visual Analogue Scale (VAS) scores, incision drainage volume, and incision-related complications were collected and compared between the two groups.

NCT ID: NCT05597150 Completed - Healthy State Clinical Trials

The Exploration of the Regulatory Effect of Magnesium on Intestinal Flora in Healthy Adults

Start date: October 15, 2022
Phase: N/A
Study type: Interventional

In this A Single-center, Prospective, Self-controlled trial, subjects should avoid a high-magnesium diet for 1-3 weeks and take magnesium supplements for 4-6 weeks.

NCT ID: NCT05597137 Completed - Healthy Clinical Trials

The Exploration of the Regulatory Effect of Zinc on Intestinal Flora in Healthy Adults

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

In this A Single-center, Prospective, Self-controlled trial, subjects should avoid a high-Zinc diet for weeks 1-2 and take Zinc supplements for weeks 3-4