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NCT ID: NCT06363565 Recruiting - Homocysteine Clinical Trials

Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether supplementation of compound nutrients, including folic acid, vitamin B6, vitamin B12, and betaine, will decrease the level of plasma homocysteine in Chinese adults with homocysteine levels above 10 μmol/L.

NCT ID: NCT06363552 Not yet recruiting - Clinical trials for Metastatic Colorectal Cancer

A Study of SC-0191 in Subjects With Metastatic Colorectal Cancer

Start date: May 2024
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to evaluate the preliminary safety and efficacy of SC0191 as single agent or in combination with bevacizumab or 5-FU/LV in advanced colorectal cancer.

NCT ID: NCT06363422 Completed - Clinical trials for Patient Satisfaction

The Value of Epicanthoplasty on the Modification of Upper-eyelid Appearance

Start date: January 1, 2024
Phase:
Study type: Observational

In East Asian populations, the combination of an epicanthic fold and mono-eyelid is one of their anatomical characteristics. Misalignment of the orbicularis oculi muscle and fibrous connections leads to longitudinal tension, forming the epicanthic fold. The epicanthic fold may diminish the aesthetic effects of eyelid cosmetic surgery, shorten the horizontal length, and affect the postoperative shape of double eyelids. As upper eyelid cosmetic surgery is one of the most common cosmetic procedures in Asia, there is increasing attention on the modification of the epicanthic fold and its impact on the formation of double eyelids.

NCT ID: NCT06363370 Recruiting - Clinical trials for Respiratory Syncytial Virus Infections

Human Interferon α1b Inhalation Solution Against Respiratory Syncytial Virus in Children With Lower Respiratory Tract Infections

Start date: March 27, 2024
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy and safety of interferon α1b (GB05) in the treatment of children under 2 years of age with respiratory syncytial virus infection.

NCT ID: NCT06363162 Recruiting - Glioma Clinical Trials

Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

To distinguish various molecular subtypes of gliomas by spectra data obtained from Raman analyzer, including IDH mutant, 1p/19q-codeleted, ATRX deletion, TERT promoter mutation, MGMT promoter methylation, EGFR amplification, H3 K27-altered, TP53 mutant, PTEN deficiency, ki 67, AQP4, VEGF, and so on, comparing with the results of Immunohistochemistry or genetic test on the same brain tissue samples.

NCT ID: NCT06363123 Recruiting - Breast Cancer Clinical Trials

Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis

Start date: March 29, 2024
Phase:
Study type: Observational

The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from multi-cancer patients using advanced mass spectrometry detection technology, in conjunction with metabolomics approaches. The goal is to construct a plasma metabolite database for multi-cancer patients. Simultaneously, we will delve into the exploration and validation of a series of metabolic biomarkers for early multi-cancer diagnosis. The objective is to establish a safer, more convenient, and more sensitive early screening method, thereby providing a reliable scientific foundation and critical evidence for improving the early diagnostic process for individuals at high risk of multi-cancer.

NCT ID: NCT06363006 Recruiting - Clinical trials for Hepatocellular Carcinoma

Combination of Cardonizumab Injection and TKI Second Line Therapy for Advanced Hepatocellular Cancer

Start date: March 11, 2024
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to evaluate the efficacy and safety of cardonilizumab injection combined with TKI in second-line treatment of advanced hepatocellular carcinoma. The main questions it aims to answer are: - Objective response rate (ORR) for evaluation - Disease Control Rate (DCR); Duration of relief (DoR); Progression free survival (PFS); Total survival time (OS); Safety。

NCT ID: NCT06362967 Not yet recruiting - Clinical trials for High Titers of Anti-HLA Antibody (MFI =5000)

The Efficacy and Safety of Desensitation Regimen for Patients With High Titers of Anti-HLA Antibodies Prior to Allo-HSCT

Start date: May 1, 2024
Phase: Phase 2
Study type: Interventional

Evaluation of the efficacy and safety of immunoadsorption or plasma exchange combined with rituximab and high-dose IVIG to reduce high titres of anti-HLA antibodies in patients prior to allogeneic haematopoietic stem cell transplantation

NCT ID: NCT06362902 Recruiting - Colon Cancer Clinical Trials

Laparoscopic Right Hemicolectomy With Transrectal Specimen Extraction for Colon Cancer

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the preliminary surgical outcomes of laparoscopic right hemicolectomy with transrectal specimen extraction. The hypothesis is that this type of natural orifice specimen extraction surgery (NOSES) could achieve good short-term and oncological outcomes for right colon cancer patients.

NCT ID: NCT06362512 Recruiting - Stroke Clinical Trials

Cognitive-motor Exercise for Stroke Patients in Function, Cognition and Related Brain Changes.

COGMOTION
Start date: April 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate a cognitive-motor exercise on dual-task interference during dual-task ankle movement and the corresponding alterations of brain activity.