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NCT ID: NCT00105443 Completed - Clinical trials for Carcinoma, Hepatocellular

A Phase III Study of Sorafenib in Patients With Advanced Hepatocellular Carcinoma

SHARP
Start date: March 2005
Phase: Phase 3
Study type: Interventional

The purpose of the study is: Find out if patients receiving sorafenib will live longer. Find out if sorafenib has any effect on patient reported outcomes. Find out if sorafenib prevents the growth of or shrinks liver tumors and/or their metastases. Determine the pharmacokinetics (PK) in patients with liver cancer.

NCT ID: NCT00105248 Completed - Clinical trials for Respiratory Tract Infections

Patient Centered Communication Training to Reduce Antibiotic Use in Acute Respiratory Tract Infections

Start date: January 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of a short training program for general practitioners in patient-centered communication to reduce antibiotic prescription for acute respiratory tract infections (ARTI).

NCT ID: NCT00105144 Completed - Candidiasis Clinical Trials

Study of Micafungin in Patients With Invasive Candidiasis or Candidemia

Start date: September 2004
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine the safety and effectiveness of two dose levels of micafungin versus caspofungin in the treatment of proven invasive candidiasis or candidemia.

NCT ID: NCT00104936 Terminated - Clinical trials for Brain and Central Nervous System Tumors

Radiotherapy or Radiosurgery Compared With Observation Alone in Treating Patients With Newly Diagnosed, Benign Meningioma That Has Been Partially Removed by Surgery

Start date: December 2004
Phase: Phase 3
Study type: Interventional

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Radiosurgery may be able to send x-rays directly to the tumor and cause less damage to normal tissue. Giving radiation therapy or radiosurgery after surgery may kill any remaining tumor cells. It is not yet known whether radiation therapy or radiosurgery is more effective than observation alone in treating benign meningioma. PURPOSE: This randomized phase III trial is studying radiation therapy or radiosurgery to see how well they work compared to observation alone in treating patients with newly diagnosed, benign meningioma that has been partially removed by surgery.

NCT ID: NCT00104624 Terminated - Breast Cancer Clinical Trials

Docetaxel in Treating Older Women With Metastatic Breast Cancer

Start date: May 2005
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase II trial is studying how well docetaxel works in treating older women with metastatic breast cancer and whether it helps improve the ability to perform daily activities.

NCT ID: NCT00103844 Completed - Clinical trials for Chronic Myeloid Leukemia

Dasatinib (BMS-354835) Versus Imatinib Mesylate in Subjects With Chronic Myeloid Leukemia

Start date: February 2005
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to estimate the major cytogenetic response rates of BMS-354825 and imatinib (800 mg/d) in subjects with chronic phase, Philadelphia chromosome positive, chronic myeloid leukemia (PH+ CML) with disease resistant to imatinib at a dose of 400-600 mg/d.

NCT ID: NCT00103285 Completed - Clinical trials for Acute Lymphoblastic Leukemia

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Start date: April 11, 2005
Phase: Phase 3
Study type: Interventional

This randomized phase III trial is studying different combination chemotherapy regimens and comparing how well they work in treating patients with newly diagnosed acute lymphoblastic leukemia. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells.

NCT ID: NCT00102466 Completed - Clinical trials for Diabetes Mellitus, Type 2

Vildagliptin Compared to Gliclazide in Combination With Metformin in Patients With Type 2 Diabetes

Start date: January 2005
Phase: Phase 3
Study type: Interventional

This study is not being conducted in the United States. Many people with type 2 diabetes cannot maintain target blood glucose levels when taking a single oral drug. The purpose of this study is to assess the safety and effectiveness of vildagliptin, an unapproved drug, compared to that of gliclazide in lowering overall blood glucose levels when added to metformin in people with type 2 diabetes not at target blood glucose levels on metformin alone.

NCT ID: NCT00102388 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of Vildagliptin Compared to Gliclazide in Drug Naive Patients With Type 2 Diabetes

Start date: January 2005
Phase: Phase 3
Study type: Interventional

This study is not being conducted in the United States. The purpose of this study is to assess the safety and effectiveness of vildagliptin, an unapproved drug, compared to gliclazide in lowering overall blood glucose levels in people with type 2 diabetes who have not been previously treated with drug therapy to lower their blood sugar.

NCT ID: NCT00102128 Terminated - Clinical trials for Ischemic Heart Disease

Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack.

Start date: November 2002
Phase: Phase 2
Study type: Interventional

Study to examine the safety and effectiveness of implanted skeletal muscle cells (cells removed from the thigh muscle) into scarred areas of heart muscle after heart attack.