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NCT ID: NCT05300126 Completed - Palliative Care Clinical Trials

Brief Hypnosis Intervention for Palliative Care Patients and Their Relatives.

HypnoPal
Start date: February 14, 2022
Phase: N/A
Study type: Interventional

The study objective is to assess the feasibility of hypnosis sessions for palliative care patients in home care and of their relatives. The intervention consists of four 15-minute hypnosis sessions for the patients and for one family member, taking place at the patient's home. Recordings will be given to practice self-hypnosis.

NCT ID: NCT05298917 Completed - Cornea Clinical Trials

Influence of Silicone Hydrogel Extended Contact Lens Wear on Corneal Sensitivity

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Soft contact lens wear reduces the amount of oxygen reaching the eye, which may have an influence on corneal sensitivity. The aim of this study is to measure corneal sensitivity with means of liquid jet esthesiometry at baseline and after 6 days of continuous, extended contact lens wear.

NCT ID: NCT05297760 Active, not recruiting - Allergic Rhinitis Clinical Trials

Intralymphatic Immunotherapy With Polvac Grass & Rye Allergen Extract

Start date: February 10, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

The primary goal is to investigate the efficacy of intralymphatic immunotherapy (ILIT) for the treatment of allergic rhinitis and allergic asthma due to sensitisation to grass pollen allergens. 60 patients with allergic rhinitis will be included and randomized to receive either Polvac (n=30) or placebo (n=30). All patients will receive three injections with 4-8 weeks interval. The injections into a inguinal lymph node is guided by sonography. Patients will record symptoms and medication use in the summer of 2022 and 2023.

NCT ID: NCT05297435 Completed - Clinical trials for Trauma, Psychological; Somatic

Psychotraumatology in Somatic Medicine

Start date: January 19, 2021
Phase:
Study type: Observational [Patient Registry]

Psychotraumatology is clinically highly relevant, especially in the medical-somatic disciplines. Despite progress in recent decades, the clinical care is still inadequate - with unfavorable health effects for affected patients. There are avoidable burdens for involved clinicians and the health care system as a whole, also in terms of costs. With this background, our long-term project combines different research levels. Besides clarifying the clinical phenomenon, it aims to examine 1) the influence of traumatization on the physician-patient interaction as well as 2) the current psychological stress of the patients. Furthermore, 3) moderating factors on the side of the physicians, such as professional experience on the physician-patient interaction will be examined.

NCT ID: NCT05297058 Active, not recruiting - Aging Clinical Trials

Association of Chronological Age, Subjective Age and Bio-functional Age With Serum Anti-müllerian Hormone

Start date: July 1, 2022
Phase:
Study type: Observational

This study aims to assess the association between aging and serum anti-müllerian hormone.

NCT ID: NCT05294978 Recruiting - Retinal Dystrophies Clinical Trials

EyeConic: Qualification for Cone-Optogenetics

Start date: July 1, 2021
Phase:
Study type: Observational

This study aims to prepare for the first-in-human clinical trial of cone optogenetics vision restoration. As a first step, this worldwide multicenter ocular imaging study (EyeConic Study) is performed to identify eligible patients.

NCT ID: NCT05294965 Completed - Thermogenesis Clinical Trials

Beta 2 Adrenergic Stimulation vs Cold Exposure to Activate Human Brown Adipose Tissue

ASCENT
Start date: April 27, 2022
Phase: Early Phase 1
Study type: Interventional

The purpose of the study is to asses brown adipose tissue activity in humans after intravenous administration of the selective beta-2-adrenergic agonist fenoterol as compared to the natural activator of brown adipose tissue, a mild cold stimulus.

NCT ID: NCT05294887 Recruiting - Clinical trials for Coronary Artery Disease

Randomized Trial to Examine a Differential Therapeutic Response in Symptomatic Patients With Non-obstructive Coronary Artery Disease

EXAMINE-CAD
Start date: March 4, 2022
Phase: Phase 4
Study type: Interventional

EXAMINE-CAD-DZHK22 is a prospective, randomized, double-blind, placebo-controlled, crossover trial investigating the efficacy of beta blocker (bisoprolol) and calcium channel blocker (diltiazem) therapy in symptomatic patients with non-obstructed coronary arteries according to coronary physiological testing results.

NCT ID: NCT05294627 Completed - Prostate Cancer Clinical Trials

Validation of the Stockholm3 Test for Detection of Prostate Cancer in the Swiss Population

Start date: January 1, 2020
Phase:
Study type: Observational

The purpose of this study is to collect blood samples to investigate the prognostic performance of the STHLM3 test in a population of Swiss and German men suspected of harbouring prostate cancer based on a combination of elevated PSA levels (e.g. >2.5 ng/ml) and/or pathological digital rectal examination and/or MRI-findings.

NCT ID: NCT05293834 Recruiting - Forensic Psychiatry Clinical Trials

Virtual Reality Aggression Prevention Training (VRAPT) for (Forensic) Psychiatric Patients

Start date: September 21, 2022
Phase: N/A
Study type: Interventional

Violent and aggressive behavior as well as disorders related to aggressive behavior are highly common in both adult and juvenile forensic psychiatric patients, and is also present in a subgroup of non-forensic psychiatric in- and out-patients. One promising new treatment option is Virtual Reality. A newly developed program in this area is the Virtual Reality Aggression Prevention Training (VRAPT). The purpose of the current feasibility and pilot study is to test VRAPT in a Swiss forensic and non-forensic psychiatric setting, including both adult and juvenile patients, and to examine whether VRAPT is an effective treatment method for aggressive behavior.