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NCT ID: NCT00038480 Completed - HIV Infections Clinical Trials

Safety and Effectiveness of Lopinavir/Ritonavir in HIV Infected Infants

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to find out if the drug lopinavir/ritonavir (LPV/RTV) is safe and well tolerated in HIV infected infants. This study will also determine the most effective dose of LPV/RTV for infants.

NCT ID: NCT00038103 Completed - Breast Neoplasms Clinical Trials

Open-Label Study Of Exemestane With Or Without Celecoxib In Postmenopausal Women With ABC Having Progressed On Tamoxifen

Start date: January 2002
Phase: Phase 2
Study type: Interventional

This is an open-label, multicenter, randomized (1:1 randomization ratio) study of either exemestane or exemestane plus celecoxib in postmenopausal women with ABC having progressed on tamoxifen.

NCT ID: NCT00036647 Completed - Clinical trials for Carcinoma, Non-small-cell Lung

OSI-774 (Tarceva) in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Start date: November 1, 2001
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if OSI-774 will improve overall survival of patients with incurable stage IIIB/IV non-small cell lung cancer compared to standard of care. OSI-774 is a new type of drug under evaluation called an epidermal growth factor receptor (EGFR). OSI-774 is an investigational drug that has not yet been approved by the U.S. Food and Drug Administration (FDA).

NCT ID: NCT00036088 Completed - Schizophrenia Clinical Trials

Olanzapine Versus An Active Comparator in the Treatment of Schizophrenia

Start date: August 2001
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine how Olanzapine compares to an active comparator in the treatment of schizophrenia

NCT ID: NCT00035425 Completed - Febrile Neutropenia Clinical Trials

Treatment of Neutropenic Patients With Fever Who Are Suspected to Have A Gram Positive Infection

Start date: November 2001
Phase: Phase 3
Study type: Interventional

This study will treat patients who have fever and neutropenia (after cancer chemotherapy) that is possibly due to a specific bacteria (gram positive bacteria).

NCT ID: NCT00034853 Completed - Clinical trials for Arthritis, Juvenile Rheumatoid

Meloxicam [Mobic] in Juvenile Rheumatoid Arthritis (JRA)

Start date: December 2000
Phase: Phase 3
Study type: Interventional

To obtain safety, efficacy, pharmacokinetic and dosing information for meloxicam oral suspension in children with Juvenile Rheumatoid Arthritis (JRA)

NCT ID: NCT00029913 Completed - HIV Infections Clinical Trials

A Study of Patients Who Develop HIV Infection After Enrolling in HIV Vaccine Trials or HIV Vaccine Preparedness Trials

Start date: April 2002
Phase: N/A
Study type: Observational

Despite risk reduction counseling, some individuals in HIV vaccine trials or vaccine preparedness studies may engage in risk behavior that results in HIV infection. The purpose of the HVTN 403 study is to find out more about how persons respond to HIV infection if they have received an experimental HIV-1 vaccine before they became HIV infected. Some people in HVTN 403 received an experimental HIV vaccine as a participant in a clinical trial before getting infected with HIV. Other people in this study were in a vaccine preparedness study when they got infected with HIV. None of these individuals became infected with HIV as result of their participation in an HIV vaccine or vaccine preparedness study. HVTN 403 will compare immune responses between those who previously received an experimental HIV vaccine and those who did not. Information learned from this study may be important in guiding future developments of new HIV vaccines and other treatments for HIV and AIDS.

NCT ID: NCT00028301 Completed - HIV Infections Clinical Trials

Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success With Protease Inhibitor-Containing HAART Regimen(s)

Start date: February 2001
Phase: Phase 3
Study type: Interventional

This study will compare 2 treatments in the way they affect cholesterol levels and the amount of HIV in the blood.

NCT ID: NCT00027352 Completed - HIV Infections Clinical Trials

A Comparison of Two Ways to Manage Anti-HIV Treatment (The SMART Study)

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of this study is to compare two ways of using anti-HIV drugs to help health care providers and patients decide how to best use anti-HIV treatments over many years. Many health care providers now treat patients with daily drugs to keep the viral load as low as possible. This approach helps patients with CD4 counts less than 200-250 cells/mm3 live longer without serious diseases. But it is not known if this is the best way to treat patients with higher CD4 counts. There is information suggesting that these patients may be able to wait to use anti-HIV drugs while CD4 counts are above 250 cells/mm3. Because this study will be carried out over several years, it will provide information on the long-term advantages and disadvantages of these two treatment strategies.

NCT ID: NCT00026338 Completed - Pancreatic Cancer Clinical Trials

Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer

Start date: October 29, 2001
Phase: Phase 3
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Biological therapies such as erlotinib use different ways to stimulate the immune system and stop cancer cells from growing. Combining chemotherapy and biological therapy may kill more tumor cells. It is not yet known if gemcitabine is more effective with or without erlotinib in treating pancreatic cancer. PURPOSE: Randomized phase III trial to determine the effectiveness of gemcitabine with and without erlotinib in treating patients who have unresectable locally advanced or metastatic pancreatic cancer.