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NCT ID: NCT03985774 Completed - Carotid Stenosis Clinical Trials

The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Study

DW-MRI OUS
Start date: February 26, 2015
Phase:
Study type: Observational [Patient Registry]

The goal of this study is to evaluate the incidence of post procedure DW-MRI lesions (relative to baseline) and debris captured in the ENROUTE Transcarotid NPS inline filter during a transcarotid stenting procedure.

NCT ID: NCT03985150 Completed - Clinical trials for Peripheral Arterial Disease

Biomechanical Analysis of Arterial Tissue From Patient Suffering From Peripheral Artery Disease in the Lower Limb

Start date: September 16, 2019
Phase:
Study type: Observational

The current treatment approaches for peripheral artery disease are largely unsatisfactory. Therefore, diseased tissue will be collected as well as patient-specific arterial geometries. The tissue will be tested microstructurally and mechanically to obtain data required to optimize treatment methods through in silico modeling.

NCT ID: NCT03983564 Completed - Clinical trials for Obstructive Sleep Apnea

Derivation and Validation of a Combination of BOSTON Score and DES-OSA Score for Selection of OSA Patients.

Start date: September 1, 2021
Phase:
Study type: Observational

Derivation and Validation of a combination of BOSTON score and DES-OSA score to exclude OSA or to confirm OSA in patients.

NCT ID: NCT03982654 Completed - Labour Onset Clinical Trials

Investigating the Physiology of Labour and Labour Onset Through Longitudinal Measurements Performed With a Wearable Sensor

Start date: March 30, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to collect data to support the development and validation of a machine learning model for the automatic detection, prediction and monitoring of labour, through the use of a wearable sensor (Bloomlife sensor) that can be easily used at home. Women participating in the study will be asked to regularly record data with the Bloomlife sensor, from inclusion in the study until delivery. In addition, clinical information related to their pregnancy and delivery will be collected.

NCT ID: NCT03982186 Completed - Clinical trials for Hepatitis B, Chronic

A Study of Different Combination Regimens Including JNJ-73763989 and/or JNJ-56136379 for the Treatment of Chronic Hepatitis B Virus Infection

REEF-1
Start date: August 1, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to establish the dose-response relationship for antiviral activity of 3 dose levels of JNJ-73763989+nucleos(t)ide analog (NA) and to evaluate the efficacy of combination regimens of JNJ-73763989+NA (with and without JNJ-56136379) and of JNJ-56136379+NA.

NCT ID: NCT03981809 Completed - Cancer Pain Clinical Trials

Screening Tool to Identify the Dominant Pain Mechanism in Cancer Survivors: PainsCan

PainsCan
Start date: June 13, 2019
Phase:
Study type: Observational [Patient Registry]

Development and internal validation of an easy-to-use tool for clinical pain assessment. The tool has to be applicable in any clinical practice and without the need for expensive and complicated hospital tools to identify the source of persistent pain after the treatment of cancer.

NCT ID: NCT03981237 Completed - Post-operative Pain Clinical Trials

Postoperative Pain After Ultrasonically and Laser-activated Irrigation During Root Canal Treatment

Start date: March 25, 2019
Phase: N/A
Study type: Interventional

The aim of this prospective, randomized clinical study is to compare the frequency and intensity of post-operative pain after root canal treatment with ultrasonically-activated or laser-activated irrigation.

NCT ID: NCT03980080 Completed - Healthy Subjects Clinical Trials

Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of OSE-127 in Healthy Subjects

Start date: December 19, 2018
Phase: Phase 1
Study type: Interventional

This study is a first-in-human phase I randomised, double-blind, placebo-controlled, evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Single (IV and SC) and Multiple (IV only) Ascending Doses of OSE-127 in Healthy Subjects.

NCT ID: NCT03979989 Completed - Pharmacokinetic Clinical Trials

Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol)

Start date: September 28, 2005
Phase: Phase 1
Study type: Interventional

This was a single center, open-label, two-way crossover, drug-drug-interaction study to determine the effect of multiple dosing of omeprazole on 4 consecutive days on the pharmacokinetics of a single dose of an immediate-release capsule of CG5503 (tapentadol) in healthy participants.

NCT ID: NCT03979313 Completed - Clinical trials for Respiratory Syncytial Virus Infections

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY)

MELODY
Start date: July 23, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics (PK), and antidrug antibody (ADA) response for MEDI8897 in healthy late preterm and term infants who are 35 weeks or greater gestational age and entering their first RSV season.