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NCT ID: NCT00622609 Completed - Clinical trials for Cerebrovascular Accident

Anti-MAG First Administration to Human

Start date: August 1, 2007
Phase: Phase 1
Study type: Interventional

GSK249320 is a monoclonal antibody directed against myelin associated glycoprotein (MAG), a protein that inhibits axonal regeneration. GSK249320 acts as a MAG antagonist, and through this activity it is hypothesised that it will enhance recovery from neuronal degeneration following acute axonal injury, which occurs in spinal cord injury or stroke.

NCT ID: NCT00622583 Completed - Hernia Clinical Trials

International Hernia Mesh Registry

IHMR
Start date: September 1, 2007
Phase:
Study type: Observational

This is an open-label, multi-center, long-term, prospective hernia mesh registry. A minimum of 4,800 hernia patients will be enrolled from approximately 60 active sites globally

NCT ID: NCT00622245 Terminated - Clinical trials for Depression in Patients With Bipolar Disorder

Efficacy and Safety of Lu AA34893 in Patients With Bipolar Depression

Start date: January 2008
Phase: Phase 2
Study type: Interventional

This study will evaluate the efficacy and safety of different doses of Lu AA34893 in the treatment of depression in patients with bipolar disorder.

NCT ID: NCT00622089 Terminated - Type 2 Diabetes Clinical Trials

Open Label Safety & Pharmacodynamic Study 24Wk w/DIO-902 Combo w/Metformin & Atorvastatin in T2DM Patients

Start date: January 2008
Phase: Phase 2/Phase 3
Study type: Interventional

DiObex Inc. is developing an experimental drug (DIO-902) that is made up of part of the ketoconazole molecule for the treatment of elevated blood glucose associated with type 2 diabetes mellitus. Ketoconazole (Nizoral®) is a drug available by prescription for the treatment of fungal infections however DIO-902 is an investigational drug. DIO-902 may lower blood glucose by lowering levels of a naturally occurring hormone called cortisol. Elevated cortisol may contribute to the development of type 2 diabetes.

NCT ID: NCT00621244 Completed - Multiple Myeloma Clinical Trials

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

Start date: March 1, 2003
Phase: Phase 1/Phase 2
Study type: Interventional

This study evaluated safety, tolerability, pharmacokinetics and preliminary anti-leukemic or anti-tumor activity of LBH589B in adult patients with advanced hematological malignancies

NCT ID: NCT00620542 Completed - Clinical trials for Coronary Atherosclerosis

CRESTOR Athero Imaging Head to Head IVUS Study

SATURN
Start date: January 2008
Phase: Phase 3
Study type: Interventional

A 104-week, randomized, double-blind, parallel group, multi-center Phase IIIb study comparing the effects of treatment with rosuvastatin 40 mg or atorvastatin 80 mg on atherosclerotic disease burden as measured by intravascular ultrasound in patients with coronary artery disease.

NCT ID: NCT00620529 Completed - Clinical trials for Polycystic Ovary Syndrome

The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome

fops
Start date: February 2008
Phase: Phase 4
Study type: Interventional

We hypothesise that fish oils will have a beneficial effect on cardiometabolic parameters in women with PCOS. The purpose of this study therefore is to examine the effects of fish oils on blood pressure, heart rate variability and liver fat content in obese women with the polycystic ovary syndrome.

NCT ID: NCT00619957 Completed - Other Osteoporosis Clinical Trials

Efficacy and Safety of Risedronate Therapy Administered 35 mg Once A Week in Men With Osteoporosis

Start date: June 2002
Phase: Phase 3
Study type: Interventional

Two year study to determine the safety and efficacy of weekly 35 mg Risedronate doses in men with osteoporosis followed by a two year follow-up study.

NCT ID: NCT00618722 Completed - Clinical trials for Moderate or Severe Submental Fullness

Phase 1-2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat

ATX-101
Start date: August 2007
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the safety and potential efficacy of deoxycholic acid injection compared to placebo for the reduction of submental fat (fat below the chin).

NCT ID: NCT00618618 Completed - Clinical trials for Moderate or Severe Submental Fullness

Phase 2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat

Start date: April 2008
Phase: Phase 2
Study type: Interventional

Phase 2 trial to evaluate the safety and potential efficacy of one concentration of deoxycholic acid injection, given in three dosing paradigms, compared to placebo for the reduction of submental fat (fat beneath the chin).