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NCT ID: NCT00128492 Completed - Cystic Fibrosis Clinical Trials

Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Cystic Fibrosis (CF) Patients With Pseudomonas Aeruginosa (PA)

AIR-CF3
Start date: August 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety and efficacy of multiple courses of AZLI in patients with cystic fibrosis (CF) and lung infection due to Pseudomonas aeruginosa (PA).

NCT ID: NCT00127972 Completed - HIV Infections Clinical Trials

2NN & CHARM Long-Term Follow-up Study

Start date: February 2004
Phase: Phase 4
Study type: Interventional

It is desirable to obtain extended follow up data on subjects who participated in the 2NN study and the CHARM study in order to see if the beneficial effect of using nevirapine continues up to 144 weeks of treatment.

NCT ID: NCT00127855 Completed - Clinical trials for Haemophilus Influenzae Type b

Dose Ranging Study of Combined Haemophilus Influenzae Type B-Meningococcal Serogroups CY (Hib-MenCY-TT) Vaccine

Start date: March 1, 2003
Phase: Phase 2
Study type: Interventional

This study evaluated the safety and immunogenicity of 3 formulations of Hib-MenCY-TT vaccine compared to 2 control groups receiving licensed meningococcal serogroup C conjugate vaccine and/or licensed Hib conjugate vaccine administered at 2, 4, and 6 months of age. Antibody persistence and immune responses to polysaccharide vaccine boosters were additionally assessed at 11 to 14 months of age.

NCT ID: NCT00127556 Completed - Blood Transfusion Clinical Trials

Transfusion Medicine - Prevention of Bedside Errors

Start date: April 2005
Phase: N/A
Study type: Interventional

This study concerns the safety of blood transfusion. Prior to transfusion, staff should perform a number of essential safety checks to ensure that the correct patient is receiving the correct blood product. Evidence suggests that these safety checks are not always done. This study has been designed to assess the effect of a simple intervention on the performance of the bedside safety check. The hypothesis is that a simple intervention will improve the performance of the bedside check.

NCT ID: NCT00127283 Completed - Clinical trials for Acquired Bleeding Disorder

Recombinant Factor VIIa in Acute Intracerebral Haemorrhage

FAST
Start date: May 2005
Phase: Phase 3
Study type: Interventional

This trial is conducted in Asia, Europe, Middle East, North America, Oceania, and South America. The purpose of this study is to evaluate the treatment of Recombinant Factor VIIa (eptacog alfa (activated)) in patients with acute intracerebral bleeding. It is expected that more patients will recover without severe permanent disability after acute treatment with Recombinant Factor VIIa by reducing further intracerebral bleeding.

NCT ID: NCT00126880 Completed - HIV Infections Clinical Trials

AVX754 (a New Nucleoside Reverse Transcriptase Inhibitor [NRTI]) to Treat Drug-resistant HIV

Start date: July 2005
Phase: Phase 2
Study type: Interventional

The study will measure how safe and effective AVX754 (a new drug for the treatment of HIV) is in treating HIV-1 infected people who have failed treatment with lamivudine.

NCT ID: NCT00126295 Completed - Stroke Clinical Trials

Evaluation of an Individualised Written Education Package for Stroke Patients

Start date: June 2003
Phase: Phase 2
Study type: Interventional

The primary aim of the randomised controlled trial was to evaluate the effectiveness of a tailored written education package (“What you need to know about stroke") on the outcomes of: - Knowledge about stroke, self-efficacy, anxiety, depression, perceived health status, satisfaction with the content and presentation of the information received, and desire for additional information for patients following stroke and - Knowledge about stroke, self-efficacy, anxiety, depression, satisfaction with the content and presentation of the information received, and desire for additional information for their carers. A secondary aim was to evaluate the effect of written information on the outcomes of knowledge about stroke, self-efficacy, anxiety, depression, and perceived health status of patients following stroke and on knowledge about stroke, self-efficacy, anxiety, and depression of their carers.

NCT ID: NCT00125892 Completed - Fibromyalgia Clinical Trials

A Study of Duloxetine in the Treatment of Fibromyalgia

Start date: July 2005
Phase: Phase 3
Study type: Interventional

This study is designed to evaluate duloxetine for the treatment of fibromyalgia syndrome patients.

NCT ID: NCT00124761 Completed - Neoplasm Metastasis Clinical Trials

A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases

Start date: December 2002
Phase: Phase 3
Study type: Interventional

This study examines surgery versus radiosurgery (highly focussed radiation) for the treatment of cancer which has spread to one spot in the brain (solitary brain "metastasis"). For these two treatment options, it will compare patients' survival times, quality of life, control rate of the brain metastases and side effects. It uses the most rigorous scientific method available called "randomisation" which minimises biases that exist with other types of studies. It will involve 30 - 40 patients.

NCT ID: NCT00124449 Completed - Clinical trials for Arthritis, Rheumatoid

Study of Abatacept Versus Placebo to Assess the Prevention of Rheumatoid Arthritis (RA) in Adult Patients

Start date: February 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess if Abatacept given for six months will prevent rheumatoid arthritis (RA) in patients who are at risk for the development of RA in comparison to placebo. High risk patients are defined as those having a positive laboratory test for anti-cyclic citrullinated peptide (anti-CCP2).