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NCT ID: NCT02538848 Completed - Clinical trials for Type 2 Diabetes Mellitus

Study of HTD4010 in Healthy Volunteers

Start date: October 2015
Phase: Phase 1
Study type: Interventional

To investigate safety and tolerability of HTD4010 after single ascending doses (SAD) in healthy volunteers

NCT ID: NCT02538666 Completed - Lung Cancer Clinical Trials

An Investigational Immuno-therapy Study of Nivolumab, or Nivolumab in Combination With Ipilimumab, or Placebo in Patients With Extensive-Stage Disease Small Cell Lung Cancer (ED-SCLC) After Completion of Platinum-based Chemotherapy

CheckMate 451
Start date: October 13, 2015
Phase: Phase 3
Study type: Interventional

In this study, all patients must have already completed first-line chemotherapy to treat extensive-stage disease small cell lung cancer. The purpose of this study is to show that nivolumab, or nivolumab plus ipilimumab followed by nivolumab by itself, will prolong overall survival when administered as consolidation treatment in patients that are stable or responding after chemotherapy. Patients receiving treatment will be compared with patients taking placebo.

NCT ID: NCT02538653 Completed - Clinical trials for Metabolic Disorder; Carbohydrate, Absorption, Intestine

Determination of the Postprandial Responses to Two Cereal Foods Differing by Their SDS Content Consumed Alone.

Start date: September 2015
Phase: N/A
Study type: Interventional

This study aimed at determining the 4-hours postprandial blood glucose and insulin responses to the ingestion of cereal product differing by their SDS content.

NCT ID: NCT02538640 Completed - Clinical trials for Metabolism and Nutrition Disorders

Determination of the Postprandial Responses to Two Cereal Foods Differing by Their SDS Content and GI Consumed Alone.

Start date: August 2015
Phase: N/A
Study type: Interventional

This is a laboratory-based research study conducted in two parts. Open cross-over design. 2 test sessions per subject included in the study. It aims at determining the postprandial blood glucose and insulin responses to the ingestion of cereal product differing by their SDS content and GI in 20 healthy non-smoking voluntary subjects, aged from 18 to 45 years.

NCT ID: NCT02536404 Completed - Ulcerative Colitis Clinical Trials

Extension Study of APD334-003 in Patients With Moderately to Severely Active Ulcerative Colitis

Start date: January 25, 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether etrasimod (APD334) is a safe and effective treatment for ulcerative colitis after 52 weeks of treatment.

NCT ID: NCT02536300 Terminated - Follicular Lymphoma Clinical Trials

Dose Optimization Study of Idelalisib in Follicular Lymphoma

Start date: January 14, 2016
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to establish a safe and effective dosing regimen of idelalisib in participants with relapsed or refractory follicular lymphoma (FL) who have no other therapeutic options.

NCT ID: NCT02535416 Completed - Healthy Clinical Trials

A Study of ARC-520 at Varying Infusion Rates in Healthy Adult Volunteers

Start date: September 2015
Phase: Phase 1
Study type: Interventional

Single doses of ARC-520 will be evaluated at varying infusion rates and by slow bolus push.

NCT ID: NCT02535234 Completed - Clinical trials for Obstructive Sleep Apnoea

Comparison of Two Continuous Positive Airway Pressure Systems

Start date: April 2016
Phase: N/A
Study type: Interventional

Randomised crossover trial of a novel and traditional Continuous Positive Airway Pressure (CPAP) system in Obstructive Sleep Apnoea patients.

NCT ID: NCT02535091 Completed - Partial Epilepsy Clinical Trials

Safety and Pharmacokinetic Study of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures

Start date: August 3, 2016
Phase: Phase 3
Study type: Interventional

This is a multicenter, open label study to assess the safety and pharmacokinetics of YKP3089 as adjunctive therapy in subjects with partial onset seizures. Initially, subjects taking phenytoin or phenobarbital will be enrolled followed by additional subjects taking anti-epileptic drugs (AED) other than phenytoin and phenobarbital to further investigate long-term safety.

NCT ID: NCT02534935 Completed - Clinical trials for Meningococcal B Disease

Immunogenicity, Safety and Tolerability of a Neisseria Meningitidis Serogroup B Bivalent Recominant Lipoprotein 2086 Vaccine (Bivalent rLP2086) in Healthy Toddlers.

Start date: August 31, 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the immunogenicity, safety and tolerability of a new vaccine that might prevent meningococcal B disease. The study will be conducted in healthy toddlers aged between 12 and 24 months.