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NCT ID: NCT00314964 Completed - Hot Flashes Clinical Trials

Study Evaluating PD-0299685 for the Treatment of Vasomotor Symptoms (Hot Flashes / Flushes) Associated With Menopause

Start date: August 2006
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to determine if PD-0299685 is effective and safe in the treatment of vasomotor symptoms (hot flashes / flushes) associated with menopause.

NCT ID: NCT00314860 Completed - Clinical trials for Restless Legs Syndrome

RLS In Adults: Comparing Immediate Release Formulation With Extended Release Formulation Of Ropinirole

Start date: February 2006
Phase: Phase 3
Study type: Interventional

Restless Legs Syndrome (RLS) study in adults comparing immediate release ropinirole with extended release ropinirole over 12 weeks

NCT ID: NCT00314210 Completed - Anxiety Disorders Clinical Trials

Safety and Efficacy Maintenance Study of Quetiapine SR to Treat GAD Patients.

PLATINUM
Start date: March 2006
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the efficacy of quetiapine SR compared to placebo in increasing time from randomisation to an anxiety event in patients with generalised anxiety disorder (GAD). PLEASE NOTE: Seroquel SR and Seroquel XR refer to the same formulation. The SR designation was changed to XR after consultation with FDA.

NCT ID: NCT00314145 Completed - Clinical trials for Japanese Encephalitis

A Safety and Efficacy Study of Two Japanese Encephalitis Vaccines ChimeriVax™-JE and JE-VAX

Start date: November 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine non-inferiority in seroconversion and to compare the safety and tolerability between ChimeriVaxTM-JE and JE-VAX to the respective homologous virus strain after completion of vaccination course.

NCT ID: NCT00314132 Completed - Clinical trials for Japanese Encephalitis

Safety Study of ChimeriVax™-JE Vaccine to Prevent Japanese Encephalitis.

Start date: October 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess whether ChimeriVax™ JE vaccine (a new vaccine to be used for vaccination against Japanese encephalitis) is safe and well tolerated when compared to placebo (dummy) vaccination.

NCT ID: NCT00313820 Completed - Clinical trials for Central Neuropathic Pain

Efficacy Of Pregabalin In Subjects With Post-Stroke Central Neuropathic Pain

Start date: August 2006
Phase: Phase 4
Study type: Interventional

Efficacy and Safety of flexibly dosed pregabalin compared to placebo among subjects with central post stroke pain (CPSP)

NCT ID: NCT00313222 Completed - Clinical trials for Chronic Thromboembolic Pulmonary Hypertension

Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension

Start date: October 2005
Phase: Phase 3
Study type: Interventional

The present trial investigates a possible use of oral bosentan, which is currently approved for the treatment of symptoms of pulmonary arterial hypertension (PAH), to patients suffering from inoperable chronic thromboembolic pulmonary hypertension (CTEPH) because of (i) peripheral localization of thrombotic material or (ii) persistent or recurrent pulmonary hypertension after pulmonary endarterectomy.

NCT ID: NCT00312845 Completed - Clinical trials for Non-Hodgkin's Lymphoma

Study of VELCADE and Rituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the combination of VELCADE and rituximab improves progression free survival relative to rituximab alone in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma (B-NHL) who never received rituximab or who have previously responded to rituximab. This is an international study being conducted in the United States and in many countries around the world. A complete list of study locations is listed below.

NCT ID: NCT00312806 Completed - Clinical trials for Gastroesophageal Reflux Disease (GERD)

Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341)

Start date: May 2006
Phase: Phase 3
Study type: Interventional

The aim of the present study is to identify factors (such as symptom patterns and symptom scores) that influence the response to treatment with pantoprazole using different evaluation methods (e.g., ReQuest™ questionnaire, patient and investigator assessment). Pantoprazole will be administered once daily in the morning at one dose level. The study duration consists of a treatment period of 8 weeks. The study will provide further data on safety and tolerability of pantoprazole.

NCT ID: NCT00312208 Completed - Breast Cancer Clinical Trials

Docetaxel in Breast Cancer

Start date: November 2001
Phase: Phase 3
Study type: Interventional

Primary objective : - To compare disease-free survival after treatment with docetaxel in combination with doxorubicin and cyclophosphamide to doxorubicin and cyclophosphamide followed by docetaxel in operable adjuvant breast cancer HER2neu negative patients with positive axillary lymph nodes. Secondary objectives : - To compare toxicity and quality of life between the 2 above-mentioned arms. - To evaluate pathologic and molecular markers for predicting efficacy.