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NCT ID: NCT01792414 Completed - Major Depression Clinical Trials

Transcranial Electrical Stimulation (TES) for the Treatment of Depression.

Start date: January 2013
Phase: N/A
Study type: Interventional

This study is a RCT of transcranial electrical stimulation in depressed patients. Mood, cognitive test performance and biomarkers will be measured during the trial.

NCT ID: NCT01790802 Completed - Clinical trials for Age-related Macular Degeneration

Laser Intervention in Early Age-Related Macular Degeneration Study

LEAD
Start date: November 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether 2RT nanosecond laser therapy slows the progression to advanced age-related macular degeneration.

NCT ID: NCT01789749 Completed - Colonic Adenomas Clinical Trials

Soft Coagulation for the Prevention of Adenoma Recurrence

SCAR
Start date: July 2013
Phase: N/A
Study type: Interventional

Recurrence after endoscopic mucosal resection of laterally spreading lesions (LSL) >= 20mm in size occurs in approximately 20% of cases at surveillance colonoscopy. We aim to evaluate the efficacy of prophylactic adjuvant thermal ablation of the EMR mucosal defect margin in reducing adenoma recurrence following colonic EMR.

NCT ID: NCT01788163 Completed - Clinical trials for EGFR Mutation Status in aNSCLC Patients

Asia Pacific and Russia Diagnostic Study for EGFR Testing

IGNITE
Start date: February 27, 2013
Phase: N/A
Study type: Interventional

Interventional diagnostic, international, multicenter and non-comparative study of EGFR mutation status in aNSCLC patients (locally advanced and/or metastatic disease) with adenocarcinoma and non-adenocarcinoma histologies. It will be conducted in Asia Pacific and Russia and will assess the current status of EGFR mutation testing, and the concordance of EGFR mutation status derived from tumour samples and blood based circulating free DNA.

NCT ID: NCT01788046 Completed - Clinical trials for Hyperparathyroidism, Secondary

Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis

Start date: March 12, 2013
Phase: Phase 3
Study type: Interventional

This study is designed to assess the efficacy and safety of etelcalcetide (AMG 416) compared with placebo in the treatment of SHPT in CKD patients receiving hemodialysis.

NCT ID: NCT01787799 Completed - Clinical trials for Atherosclerotic Lesion(s)

EVOLVE II QCA: A Prospective, Multicenter Trial to Assess the SYNERGY Stent System for the Treatment of Atherosclerotic Lesion(s)

EVOLVE II QCA
Start date: March 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate 9 month angiographic and intravascular ultrasound (IVUS) data for the SYNERGY Everolimus-Eluting Platinum Chromium Coronary Stent System (SYNERGY Stent System) in the treatment of subjects with atherosclerotic lesion(s) ≤34 mm in length (by visual estimate) in native coronary arteries ≥2.25 mm to ≤4.0 mm in diameter (by visual estimate).

NCT ID: NCT01787747 Completed - Healthy Clinical Trials

Pharmacokinetics (PK) and Tolerability of AVP-786 in Healthy Volunteers

Start date: October 2012
Phase: Phase 1
Study type: Interventional

To assess the single- and multiple-dose pharmacokinetic (PK), safety and tolerability of AVP-786 in healthy volunteers.

NCT ID: NCT01787669 Completed - Diabetes Clinical Trials

Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema

SwitchDMO
Start date: June 2013
Phase: Phase 2
Study type: Interventional

The specific aim of the study is to test the following hypothesis: That switching between treatments from bevacizumab to Ozurdex or vice versa in eyes with diabetic macular oedema with no or incomplete response from one therapy is beneficial.

NCT ID: NCT01787552 Completed - Clinical trials for Hematologic Diseases

A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF

Start date: May 8, 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this phase Ib/II clinical trial was to: a) evaluate the safety of the co-administration of LDE225 and INC424 in myelofibrosis patients and establish a maximum tolerated dose and/or Recommended Phase II dose of the combination and b) to assess the efficacy of the co-administration of LDE225 and INC424 on spleen volume reduction.

NCT ID: NCT01787513 Completed - Depression Clinical Trials

Cognitive Bias Modification (CBM) Via Imagery and Internet Cognitive Behavioural Therapy (iCBT) for Depression

Start date: February 2013
Phase: N/A
Study type: Interventional

A randomised controlled trial comparing Internet based cognitive behavioural therapy for major depressive disorder plus a cognitive bias modification intervention (OxIGen) version A vs. Internet based cognitive behavioural therapy for major depressive disorder plus a cognitive bias modification intervention (OxIGen) version B on symptoms of depression and negative interpretation bias.