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NCT ID: NCT00294385 Completed - Breast Cancer Clinical Trials

Study Comparing Concomitant Docetaxel + Gemcitabine to Sequential Therapy of Docetaxel Followed by Gemcitabine

Start date: June 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the Time To Disease Progression (TTDP) between those patients with unresectable, locally recurrent or metastatic breast cancer who are treated with concomitant Docetaxel plus Gemcitabine to those patients treated with sequential therapy of Docetaxel followed by Gemcitabine.

NCT ID: NCT00293124 Completed - Clinical trials for Gastrointestinal Stromal Tumors

Open-label Trial of GlivecWith Unresectable or Metastatic Malignant Gastrointestinal Stromal Tumors

Start date: March 2004
Phase: Phase 3
Study type: Interventional

The rationale is to assess the clinical and biological activity of Imatinib and to compare the data with historic data. Additionally this study has been designed to gain more experience with the treatment of GIST in several Central and Eastern European Countries.

NCT ID: NCT00293046 Completed - Allergy Clinical Trials

Assessment of Grazax® Treatment Compliance

Start date: February 2006
Phase: Phase 3
Study type: Interventional

This trial is performed to assess whether the Grazax® treatment compliance can be improved by use of a compliance device (Memozax®).

NCT ID: NCT00292435 Completed - Clinical trials for Venous Insufficiency

Efficacy and Tolerability CVI (A 12-week, Double-blind, Randomised, Placebo-controlled, Multicentre Trial (CVI)

Start date: March 2006
Phase: Phase 3
Study type: Interventional

To determine efficacy and tolerability of Antistax 360 mg tablets in chronic venous insufficiency linked to edema (swelling) and subjective symptoms

NCT ID: NCT00291798 Completed - Breast Cancer Clinical Trials

Neoadjuvant Endocrinotherapy of Breast Cancer (Mamma Carcinoma) With Exemestane

Start date: September 2000
Phase: Phase 2
Study type: Interventional

The objective of the present clinical investigation is to determine whether hormonal therapy given preoperatively is able to reduce tumor size to an extent that facilitates breast-conserving procedures.

NCT ID: NCT00291759 Completed - Breast Cancer Clinical Trials

ABCSG 8 - Adjuvant Treatment in Patients With Hormone Receptor-positive Breast Cancer With Good to Moderate Differentiation.

Start date: January 1996
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the difference in event-free survival between postmenopausal women with hormone receptor-positive early breast cancer who switched from tamoxifen to anastrozole and those who continued to receive tamoxifen.

NCT ID: NCT00291330 Completed - Thromboembolism Clinical Trials

Efficacy and Safety of Dabigatran Compared to Warfarin for 6 Month Treatment of Acute Symptomatic Venous Thromboembolism

RE-COVER I
Start date: February 2006
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to determine the comparative safety and efficacy of dabigatran etexilate 150 mg bid administered orally and warfarin as needed (pro re nata - prn) to maintain an International Normalised Ratio (INR) of 2.0-3.0 for 6 month treatment of acute symptomatic venous thromboembolism (VTE), following initial treatment (5-10 days) with a parenteral anticoagulant approved for this indication. This trial aims to demonstrate non-inferiority of dabigatran compared with warfarin in patients with acute symptomatic VTE. After achieving non-inferiority, this trial also aims to establish superiority (by means of hierarchical tests) of dabigatran over warfarin.

NCT ID: NCT00289627 Completed - Melanoma Clinical Trials

A Single Arm Study of Ipilimumab Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma

Start date: April 2006
Phase: Phase 2
Study type: Interventional

The purpose of this clinical research study is to evaluate the Best Overall Response Rate (BORR), (as per modified WHO criteria) in patients with previously treated melanoma-Stage III (unresectable) or Stage IV melanoma receiving 10 mg/kg of ipilimumab. The safety of this product will also be evaluated.

NCT ID: NCT00289510 Completed - Influenza Clinical Trials

Safety and Immunogenicity Study of an Inactivated Influenza Vaccine (Whole Virion, Vero Cell Derived)

Start date: January 2006
Phase: Phase 1/Phase 2
Study type: Interventional

The objective of this study is to assess the safety and immunogenicity of inactivated influenza vaccine (whole virion, Vero cell derived). Subjects will be randomly assigned to receive a single injection of whole virion, Vero cell derived or egg derived influenza vaccine on Day 0. Subjects will return to the study site for safety evaluation at predetermined intervals for 180 days after vaccination. Subjects will also have blood drawn at predetermined intervals to measure their immunologic response to vaccination.

NCT ID: NCT00288249 Completed - Breast Neoplasms Clinical Trials

Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Breast Cancer

Start date: December 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether the study drug is effective and safe in the treatment of patients with metastatic breast cancer