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NCT ID: NCT01197560 Completed - Clinical trials for Diffuse Large B-cell Lymphoma

Study of Lenalidomide to Evaluate Safety and Effectiveness in Patients With Diffuse Large B-Cell Lymphoma (DLBCL)

Start date: September 2, 2010
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to compare lenalidomide to a control drug and see which one delays Diffuse Large B-Cell Lymphoma (DLBCL) disease progression longer.

NCT ID: NCT01196091 Completed - Clinical trials for Systemic Lupus Erythematosus

A Study of LY2127399 in Participants With Systemic Lupus Erythematosus

Start date: December 2010
Phase: Phase 3
Study type: Interventional

The purpose of this SLE study is to evaluate the efficacy, safety and tolerability of two different doses of LY2127399 administered in participants with active SLE.

NCT ID: NCT01195883 Completed - Clinical trials for Postoperative Complications

Effect of Goal-directed Crystalloid Versus Colloid Administration on Major Postoperative Morbidity

C-C
Start date: November 2010
Phase: N/A
Study type: Interventional

A trial in which patients having open abdominal surgery are randomized to receive either crystalloids or colloids intraoperatively, guided by esophageal Doppler. The investigators test the primary hypothesis that goal-directed colloid administration during elective abdominal surgery decreases a composite of postoperative complications within 30 days of surgery.

NCT ID: NCT01195584 Completed - Clinical trials for Degenerative Lumbar Disease

Minimal Access Surgical Technique (MAST) in Obese Patients in Degenerative Lumbar Disease

Start date: May 2010
Phase: N/A
Study type: Observational

The study concerns a retrospective analysis of all subjects operated as of 1st Jan 2008 using Minimal Access Surgical Technique (MAST). The study is descriptive in nature and will present the observation of all cumulated patients operated with MAST. The study data will include the general health information of the subjects prior to surgery, information on the surgery such as OP time, blood loss, and the postoperative wound healing process (until discharge), which is on average the 10th postoperative day.

NCT ID: NCT01194570 Completed - Clinical trials for Multiple Sclerosis, Primary Progressive

A Study of Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis

Start date: March 2, 2011
Phase: Phase 3
Study type: Interventional

This randomized, parallel group, double-blind, placebo controlled study will evaluate the efficacy and safety of ocrelizumab in participants with primary progressive multiple sclerosis. Eligible participants will be randomized 2 : 1 to receive either ocrelizumab or placebo.

NCT ID: NCT01193699 Completed - Polycythemia Vera Clinical Trials

Safety Study of Pegylated Interferon Alpha 2b to Treat Polycythemia Vera

PEGINVERA
Start date: August 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is the identification of the maximum tolerated dose (MTD) of the investigational medicinal product. Moreover the safety and tolerability will be assessed and an exploratory analysis of efficacy and biomarker modulation will be performed.

NCT ID: NCT01193244 Completed - Prostate Cancer Clinical Trials

Study Comparing Orteronel Plus Prednisone in Patients With Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer

Start date: October 2010
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, multicenter, phase 3 study evaluating orteronel (TAK-700) plus prednisone compared with placebo plus prednisone in the treatment of men with progressive, chemotherapy-naive, metastatic, castration-resistant prostate cancer (mCRPC)

NCT ID: NCT01191801 Completed - Clinical trials for Acute Myeloid Leukemia

Study of Vosaroxin or Placebo in Combination With Cytarabine in Patients With First Relapsed or Refractory AML

VALOR
Start date: December 17, 2010
Phase: Phase 3
Study type: Interventional

This study compared treatment groups of patients treated with vosaroxin and cytarabine versus patients treated with placebo and cytarabine.

NCT ID: NCT01188681 Completed - Clinical trials for Chronic Lymphocytic Leukemia (CLL)

Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia

Start date: September 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The objective of the first part of the study is to determine a safe dose of TRU-016 that can be used in combination with bendamustine in patients with relapsed CLL. The objectives of the second part of the study are to compare the safety and efficacy of TRU-016 in combination with bendamustine to bendamustine alone in patients with relapsed CLL.

NCT ID: NCT01185743 Completed - Schizophrenia Clinical Trials

Antipsychotics and Gene Expression in Soft Tissues

Start date: July 2010
Phase: Phase 4
Study type: Interventional

Schizophrenia is a severe chronic and disabling mental disorder and is associated with a significant reduction in life expectancy. Atypical antipsychotic treatment compliance may be jeopardized because of drug induced weight gain and abnormalities in carbohydrate and lipid metabolism. Aim: to gain data on drug related effects on gene expression and regulation with special regard to glucose metabolism.