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NCT ID: NCT06386237 Recruiting - Cognitive Change Clinical Trials

Nutritional Modulation of Cognition and Brain Activity

Start date: April 8, 2024
Phase: N/A
Study type: Interventional

The aim of the present study is to investigate the effects of different meal interventions on cognition (i.e., learning and decision making) and brain activity in healthy participants.

NCT ID: NCT06384846 Recruiting - Clinical trials for Acute Coronary Syndrome

AI Algorithms in Prediction of ACS Based on Leukocyte Properties

Start date: February 1, 2024
Phase:
Study type: Observational

The goal of this observational study is to find out if artificial intelligence (AI) can accurately predict acute coronary syndrome (ACS) using data on white blood cells in adults. The main question it aims to answer is: - Can AI algorithms based on white blood cell data predict ACS with accuracy comparable to that of high-sensitivity cardiac troponin (hs-cTn)? Researchers will look at how the AI model's predictions stack up against the standard hs-cTn blood tests to see which is more accurate in diagnosing ACS. Participants in this study will have already had blood tests as part of their usual care. Their previously collected health information and blood test results will be used to help train and test the AI algorithms. Participants will not undergo any new procedures for the study itself.

NCT ID: NCT06384365 Recruiting - Taste, Altered Clinical Trials

Interaction of Inflammation, Taste Perception and Preferences as a Function of Physical Activity and Body Composition

Start date: April 15, 2024
Phase:
Study type: Observational

The aim of this study is to investigate whether differences in taste perception and preference behavior can be attributed to inflammatory processes induced by physical activity. The focus will be on sweet taste and the perception of fat. A non-invasive, observational study design will be used.

NCT ID: NCT06383390 Not yet recruiting - Clinical trials for Overweight and Obesity

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Start date: May 2024
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/m^2 or higher and Atherosclerotic Cardiovascular Disease and/or chronic kidney disease.

NCT ID: NCT06381999 Completed - Clinical trials for Post-stroke Spasticity

Validity and Inter-rater Reliability for Early Recognition of Spasticity Using the Decision Tree Tool

I-REFER
Start date: October 27, 2023
Phase:
Study type: Observational

The aim of this study is to investigate the validity and Inter-rater reliability for early recognition of spasticity by nurses and physiotherapists using the decision tree tool.

NCT ID: NCT06376188 Completed - Communication Clinical Trials

Improving Breaking Bad News in Pediatrics by Simulated Communication

SimCom
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Breaking bad news, especially a death notice, is an essential part of the medical profes-sional communication. Being inadequately trained in those skills this may result in un-pleasant psychosocial consequences for everyone involved. This prospective, single-center, randomized controlled trial evaluated the delivery of a death notice to simulation parents out of the perspective of these parents (professional actors), the participants (students) and by video analysis. The simulation patient has prior unexpectedly died during a simulated resuscitation. The intervention group broke the bad news after receiving a short communication

NCT ID: NCT06368518 Recruiting - Clinical trials for Hypertrophic Cardiomyopathy

Austrian HCM Registry

Start date: March 8, 2024
Phase:
Study type: Observational [Patient Registry]

The Austrian Hypertrophic Cardiomyopathy (HCM) Registry is a prospective, multicenter registry enrolling patients at multiple outpatient clinics across Austria including academic and non-academic centers. Patients will undergo a structured examination process including assessment for symptoms of HCM, past medical history, concomitant medication, family history and the presence of HCM-specific red flags. Furthermore, clinical data derived from electrocardiogram, echocardiography, laboratory analysis, and genetic testing will be collected focusing on a lean variable dictionary and, in addition, specific hypothesis-driven research parameters. All data are entered into an electronic case report form (eCRF) (Phoenix Clinical Trial Management System). In order to perform multicenter analyses, data can be extracted from the eCRF after approval by the steering committee.

NCT ID: NCT06365437 Recruiting - Clinical trials for Kidney Transplantation

A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation

Start date: June 6, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of escalating doses of TCD601 when compared to rATG in de novo renal transplant patients.

NCT ID: NCT06362850 Recruiting - Cardiac Arrest Clinical Trials

Tele-Support for Emergency Medical Technicians

POHCA
Start date: April 8, 2024
Phase: N/A
Study type: Interventional

In this manikin-based simulation study the impact of tele-support during a simulated pediatric out-of-hospital cardiac arrest scenario on emergency medical technicians' guideline adherence, on gaze behavior as well as on performance of resuscitation management and cognitive load will be analyzed.

NCT ID: NCT06362083 Recruiting - Urethral Stricture Clinical Trials

Urethral Stricture Database

Start date: January 15, 2024
Phase:
Study type: Observational

Establishment of a clinical urethral stricture database for a prospective longitudinal cohort study.