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NCT ID: NCT02087579 Completed - Schizophrenia Clinical Trials

Parallel Group, Multiple Dose Pharmacokinetics Study of Five Antipsychotic Medications in Psychiatric Participants

Start date: February 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to gather information about the steady-state plasma concentrations of aripiprazole, olanzapine, quetiapine and their relevant metabolites, at various dose levels and at different time points after dosing. In addition, comparison of capillary drug concentrations vs. venous drug concentrations will be performed for aripiprazole, olanzapine, paliperidone, quetiapine, risperidone and their relevant metabolites.

NCT ID: NCT02087527 Terminated - Cellulitis Clinical Trials

Use of Corticosteroids in Children With Cellulitis

Start date: June 2014
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy of addition of corticosteroid therapy to antibiotic treatment during the first 48 hours of admission to the hospital in patients with cellulitis and its impact in the duration of the stay.

NCT ID: NCT02082548 Completed - Atrial Fibrillation Clinical Trials

Clinical Trial to Improve Treatment With Blood Thinners in Patients With Atrial Fibrillation

IMPACT-AF
Start date: June 2014
Phase: N/A
Study type: Interventional

To determine whether a comprehensive evaluation and customized multilevel educational interventions will increase the rate of use of oral anticoagulants and the adherence and persistence of use in patients with atrial fibrillation. Our hypothesis is that there will be differences in the use of oral anticoagulants and the persistence in patients between the control and interventional group. There will be a greater change in the use of oral anticoagulants over one year in the cohort in the intervention sites than the control sites. This will be due to two factors: greater initiation of oral anticoagulants among patients not treated at baseline and greater persistence of treatment for those on treatment at baseline

NCT ID: NCT02079246 Completed - Alzheimer's Disease Clinical Trials

Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease

STAR Extension
Start date: April 7, 2014
Phase: Phase 3
Study type: Interventional

To evaluate the long-term safety and tolerability of idalopirdine (Lu AE58054) as adjunctive therapy to donepezil in patients with mild-moderate Alzheimer's Disease (AD).

NCT ID: NCT02075255 Completed - Asthma Clinical Trials

Efficacy and Safety Study of Benralizumab to Reduce OCS Use in Patients With Uncontrolled Asthma on High Dose Inhaled Corticosteroid Plus LABA and Chronic OCS Therapy

Start date: April 28, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to confirm if benralizumab can reduce the use of maintenance OCS in systemic corticosteroid dependent patients with severe refractory asthma with elevated eosinophils.

NCT ID: NCT02075138 Completed - Rhinoconjunctivitis Clinical Trials

Grass Observational Study

Start date: April 2014
Phase: N/A
Study type: Observational

Grass pollen allergens are universally recognised as a major cause of allergic diseases in humans, including asthma, allergic rhinitis, conjunctivitis and dermatitis. The purpose of the current study is to evaluate allergy symptoms and allergy medication in subjects with grass-related rhinoconjunctivitis.

NCT ID: NCT02075008 Terminated - Asthma Clinical Trials

Long-term Safety Study of QGE031 in Patients With Allergic Asthma Who Completed Study CQGE031B2201

Start date: March 27, 2014
Phase: Phase 2
Study type: Interventional

This study planned to assess long-term safety of QGE031 during 12 months treatment in asthma patients who completed study CQGE031B2201.

NCT ID: NCT02071134 Recruiting - Parkinson's Disease Clinical Trials

Registry of Deep Brain Stimulation With the VERCISEā„¢ System: Vercise DBS Registry

Start date: March 4, 2014
Phase:
Study type: Observational [Patient Registry]

The purpose of this registry is to compile characteristics of world-wide outcomes for the use of Boston Scientific's commercially available Vercise DBS System in the treatment of Parkinson's disease. The utilization of Image Guided Programming (IGP), and other commercially available programming features, used as planning tools for the programming of patients with Boston Scientific's Vercise DBS System are also evaluated. Additionally, the utilization of the DBS Illumina 3D feature that may be used for the programming of patients with Boston Scientific's Vercise DBS Systems is also evaluated.

NCT ID: NCT02070978 Terminated - Clinical trials for Lupus Erythematosus, Systemic

Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Participant Who Participated in ADDRESS II)

Start date: July 29, 2014
Phase: Phase 2
Study type: Interventional

This is a multicenter, double-blind, Phase 2b, long-term extension (LTE) to the ADDRESS II core trial (EMR 700461-023) (NCT01972568), to evaluate long-term safety and tolerability of atacicept in participants with systemic lupus erythematosus (SLE). Participants who completed the 24-week core study ADDRESS II core study (NCT01972568) and thus not met any of the discontinuation criteria were invited to enter this long-term extension (LTE) study NCT02070978.

NCT ID: NCT02069704 Completed - Clinical trials for Metastatic Colorectal Cancer (mCRC)

Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients

Start date: October 29, 2014
Phase: Phase 1
Study type: Interventional

This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care.