Overactive Bladder in Elderly Patients- An Early Warning of Coronary Artery Disease

Coronary Artery Disease Clinical Trial

Official title:

Overactive Bladder in Elderly Patients- An Early Warning of Coronary Artery Disease

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02854813
• Other study ID #: 5192
• Status: Completed
• Phase: N/A
• First received: July 31, 2016
• Last updated: May 29, 2017
• Start date: January 2016
• Est. completion date: January 2017

Study information

• Verified date: May 2017
• Source: Ankara Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Investigators aimed to investigate the association between over active bladder and coronary artery disease as demonstrated on coronary angiography.

Description:

The close relationship has been demonstrated between pelvic ischemia and overactive bladder (OAB) in a study involving elderly patients. In this study, it has been found that pelvic ischemia has triggered OAB and it has been related with cardiac ischemia. The aim of this study was to delineate the correlation between OAB and the degree of coronary artery stenosis as demonstrated on coronary angiography.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 250
• Est. completion date: January 2017
• Est. primary completion date: January 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years to 90 Years

Eligibility

Inclusion Criteria:

• patients, whom were diagnosed to undergo coronary angiography in a center of cardiology

Exclusion Criteria:

• a maximum flow rate of 15 ml. per second or less,

• residual volume of 100 cc or more,

• diabetes mellitus,

• neurologic disease,

• prostate or bladder cancer,

• renal failure,

• urinary tract infection,

• nephrolithiasis or pelvic surgery,

• patients with a history of percutaneous coronary intervention or coronary artery bypass grafting

Related Conditions & MeSH terms

• Coronary Artery Disease
• Coronary Disease
• Myocardial Ischemia
• Overactive Bladder Syndrome
• Urinary Bladder, Overactive

Locations

Country	Name	City	State
Turkey	Ankara Training and Research Hospital	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Ankara Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

References & Publications (2)

De EJ, Hou P, Estrera AL, Sdringola S, Kramer LA, Graves DE, Westney OL. Pelvic ischemia is measurable and symptomatic in patients with coronary artery disease: a novel application of dynamic contrast-enhanced magnetic resonance imaging. J Sex Med. 2008 Nov;5(11):2635-45. doi: 10.1111/j.1743-6109.2008.00969.x. Epub 2008 Aug 26. — View Citation

Tarcan T, Azadzoi KM, Siroky MB, Goldstein I, Krane RJ. Age-related erectile and voiding dysfunction: the role of arterial insufficiency. Br J Urol. 1998 Dec;82 Suppl 1:26-33. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Over active bladder V8 questionnaire score		1 week