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NCT01671306 Clinical Trial

The Association Between Monocyte Subsets and Coronary Collateral Development in Diabetes Mellitus

Coronary Artery Disease Clinical Trial

Official title:
The Association Between Monocyte Subsets and Coronary Collateral Development in Diabetes Mellitus

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01671306
Other study ID # 1037
Secondary ID Samsun EAH
Status Completed
Phase N/A
First received August 18, 2012
Last updated August 22, 2012
Start date January 2011
Est. completion date October 2011

Study information
Verified date August 2012
Source Samsun Education and Research Hospital
Contact n/a
Is FDA regulated No
Health authority Turkey: Ministry of Health
Study type Observational

Clinical Trial Summary

Monocyte heterogeneity in peripheral blood seems to be important in coronary collateral development in non-diabetic patients with stable coronary artery disease. Our aim in this study is to find out any possible relationship between the levels of circulating monocyte subsets and coronary collateral development in type 2 diabetic patients.

Description:

83 diabetic patients with severe coronary artery disease were enrolled in the study. These patients were investigated according to their collateral development. Monocytes and their subtypes, namely CD14++CD16- and CD14+CD16+ cells were compared in 2 groups

Recruitment information / eligibility
Status Completed
Enrollment 83
Est. completion date October 2011
Est. primary completion date October 2011
Accepts healthy volunteers No
Gender Both
Age group 30 Years to 80 Years
Eligibility Inclusion Criteria:

- presence of > 95% stenosis of at least one major coronary artery in their first coronary angiogram.

Exclusion Criteria:

- Patients experiencing acute coronary syndrome either with or without ST elevation in the last one month

- Evidence of ongoing infection and inflammation, known malignancy and chronic kidney disease

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Samsun Education and Research Hospital
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