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NCT03738631 Clinical Trial

Cardiac Biomarkers After Marathon Running and Coronary Atherosclerosis

Coronary Artery Disease Clinical Trial

— MaraCat  

Official title:
Association of Cardiac Biomarker Elevation After Marathon Running and Coronary Atherosclerosis - the MaraCat Study

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT03738631
Other study ID # T171/2018
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date August 17, 2018
Est. completion date December 1, 2022

Study information
Verified date November 2020
Source University of Turku
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study evaluates cardiac biomarkers and their association to coronary artery disease in marathon runners.

Description:

The MaraCat study is an observational prospective study evaluating the association between cardiac biomarkers and coronary artery disease in 43 runners participating in the 2018 Paavo Nurmi Marathon. The study participants were recruited according to two age criteria - under 35 years and over 44 years of age. Comprehensive laboratory samples were collected immediately after the run, while the control workup was done in a separate visit with no significant physical excercise in the preceding two weeks. In the under 35 years -group, the control workup included an echocardiography, ecg and blood samples. In the over 44 years group, the control studies included coronary CT, echocardiography, ecg and laboratory tests.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 43
Est. completion date December 1, 2022
Est. primary completion date December 1, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 35 Years to 90 Years
Eligibility Inclusion Criteria: - Age under 35 years or over 44 years - Participant of Paavo Nurmi Marathon 2018 - Informed consent signed Exclusion Criteria: - No informed consent - existing coronary artery disease

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Finland Turku University Hospital, Heart Center Turku

Sponsors (1)
Lead Sponsor Collaborator
University of Turku

Country where clinical trial is conducted

Finland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Cardiac Troponin-T level after marathon Cardiac troponin-T levels (ng/L), [electrochemiluminescence (ECLIA) method] 0-30minutes after finishing the Paavo Nurmi Marathon
Primary Association Cardiac troponin-T level and coronary CT findings Cardiac troponin-T levels (ng/L), [electrochemiluminescence (ECLIA) method] Cardiac Troponin-T 0-30 minutes after finishing the Paavo Nurmi Marathon. Control Troponin-T levels and coronary CT angiography at control visit (>30days after marathon).
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