Coronary Arteriosclerosis Clinical Trial
Official title:
Characteristics of Culprit Lesion and Changes in Plaque Composition During Follow up in NSTEMI. A Dual Energy Cardiac CT Study
Identifying patients who are at risk for a future myocardial infarction, is still one of the
biggest challenges in cardiology.
In this study the investigators will investigate culprit lesion in patients with NSTEMI and
the ability of cardiac CT with dual energy computed tomography (DECT) scanning to describe
and identify plaques that may be vulnerable. The investigators will also describe changes in
characteristic in both stable and unstable plaques during 1 year follow up of NSTEMI and a
matching group of stable angina pectoris (SAP) patients.
Patients with verified NSTEMI undergo contrast-enhanced coronary DECT before conventional
coronary angiography (CAG), and DECT characteristics of the culprit lesion will be
determined. All Non-culprit lesions will be observed during 2 month and 1 year follow up
characteristics and changes in plaque composition, volume and core content will be assessed.
Patients with SAP undergo a baseline DECT similar to NSTEMI group. Because the expected
change in coronary plaques in SAP group is minimal, there is no need for follow up at 2
month.
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