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Clinical Trial Summary

The aim of the present study was to evaluate if the analysis of NT-proBNP might be used as an initial step for the diagnosis of chronic heart failure in patients with COPD in primary health care, and to select patients for a further examination by echocardiography.


Clinical Trial Description

Patients with a confirmed diagnosis of COPD were examined regarding chronic heart failure.

1. An interview regarding symptoms: breathlessness, orthopnoea, night cough, nocturia, walking distance.

2. Physical examination: weight and height, heart and lung auscultation, blood pressure measurement after 5 minutes' rest in the sitting position and the presence of peripheral oedema.

3. Electrocardiography.

4. Natriuretic peptide- NT-proBNP (Immulite 2500, Siemens Healthcare Diagnostics AB Sweden).

5. Patients with the NT-proBNP level of > 1200 pg/ml were referred for echocardiography to assess left ventricular function. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01801722
Study type Observational
Source Lund University
Contact
Status Completed
Phase N/A
Start date April 2008
Completion date June 2008

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