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Chronic Obstructive Pulmonary Disease clinical trials

View clinical trials related to Chronic Obstructive Pulmonary Disease.

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NCT ID: NCT04485832 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Telehealth Could Mitigate Disease Progression Compared to Standard of Care in COPD - a Randomized Controlled Trial

Start date: April 5, 2016
Phase: N/A
Study type: Interventional

The objective of this randomised controlled trial is to test, whether telehealthcare can improve HRQOL and reduce emergency admissions and hospitalisations due to AECOPD. Different outcome parameters as described in the endpoints section will be analysed.

NCT ID: NCT04485741 Completed - Asthma Clinical Trials

Strados System at Center of Excellence

Start date: September 23, 2020
Phase:
Study type: Observational

Listening to breath sounds with the stethoscope/auscultation is used by pulmonary physicians in conjunction with pulmonary function, signs and symptoms, oxygen saturation and diagnostic testing to admit, follow and discharge patients from hospital. Of these, only auscultation routinely ceases upon discharge from Hospital. Healthcare utilization statistics have shown that for more than a decade, readmission after discharge for an exacerbation of COPD or severe asthma (or chronic heart failure) remains a major problem. The Strados System has been designed to extend the range of lung sound recording both geographically and temporally to improve the standard of care when access to continuous monitoring has been replaced by periodic or no monitoring. The primary purpose of this study is to assess the clinical utility of the Strados System in enabling periodic recording and reviewing of breath sounds in patients with chronic respiratory diseases, either in the ICU, or in less continuously monitored settings, including after inpatient discharge.

NCT ID: NCT04483154 Recruiting - COPD Clinical Trials

Perry Virtual - A Prospective and Observational Rural Health Trial

Start date: August 1, 2020
Phase:
Study type: Observational

The principal objective of the study is to determine if patient-empowered, real-time and home- based patient monitoring of vital parameters can lead to: - Reduction in admission rates and improved clinical management of chronically ill patients - Reduction in use of medications - Reported quality of life A minimum of 100 patients will be recruited, monitored and observed over 6 months from home with the Coala Heart Monitor. The study population will be representative of rural, high-risk, Medicare (65+ of age) subjects with chronic conditions and will be recruited by the Perry Community Hospital in Linden, TN.

NCT ID: NCT04481555 Recruiting - COPD Clinical Trials

Eosinophil-guided Reduction of Inhaled Corticosteroids

COPERNICOS
Start date: June 28, 2021
Phase: Phase 4
Study type: Interventional

Clinical trial on eosinophil-guided time-updated person-specific reduction of inhaled corticosteroid (ICS) therapy and prophylactic azithromycin therapy in patients with severe or very severe chronic obstructive pulmonary disease (COPD) receiving long-acting b-agonist (LABA) / long-acting muscarinic receptor antagonists (LAMA) / ICS treatment.

NCT ID: NCT04479969 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Enabling Independent Living by Expanding Access to Home-Based Pulmonary Rehabilitation

Start date: March 22, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to test an existing home-based pulmonary rehab program with the addition of video chat and a capability of a Spanish version.

NCT ID: NCT04479930 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Effects of an mHealth Web-Based Platform (HappyAir) on Adherence to a Maintenance Program After Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease

Start date: December 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Objective: This study aimed to assess the effects of an integrated care plan based on an mHealth web-based platform (HappyAir) on adherence to a 1-year maintenance program applied after pulmonary rehabilitation in COPD patients. Methods: COPD patients from three hospitals were randomized to a control group or an intervention group (HappyAir group). Patients from both groups received an 8-week program of pulmonary rehabilitation and educational sessions about their illness. After completion of the process, only the HappyAir group completed an integrated care plan for 10 months, supervised by an mHealth system and therapeutic educator. The control group only underwent the scheduled check-ups. Adherence to the program was rated using a respiratory physiotherapy adherence self-report (CAP FISIO) questionnaire. Other variables analyzed were adherence to physical activity (Morisky-Green Test), quality of life (Chronic Obstructive Pulmonary Disease Assessment Test, St. George's Respiratory Questionnaire, and EuroQOL-5D), exercise capacity (6-Minute Walk Test), and lung function.

NCT ID: NCT04474717 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease in Combination With Atherosclerosis (Clinical and Biochemical Study)

Start date: November 15, 2020
Phase: N/A
Study type: Interventional

one-centered, open, non-randomized, controlled clinical trial will focus on a comprehensive study of the clinical, functional and molecular biochemical characteristics of the natural course of COPD in combination with peripheral atherosclerosis

NCT ID: NCT04473313 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Educational Follow-up in COPD Patients After Pulmonary Rehabilitation.

EDURESPI
Start date: July 16, 2020
Phase:
Study type: Observational

After pulmonary rehabilitation, the challenge is to maintain the benefits reached during the program and increase physical activity. As exercise training, education is the corner stone of pulmonary rehabilitation. Education allows to support behavioral changes in daily life. Recommendations about modalities for maintaining physical activity are still clear, however for educational follow up recommendations need to be clarified. After a pulmonary rehabilitation program, there is no defined plan for educational follow up nor location to perform education session. The aim of this study is to evaluate the proportion of patients who succeed to establish and maintain the objectives they defined during the pulmonary rehabilitation program, one year after this program.

NCT ID: NCT04467242 Recruiting - COPD Clinical Trials

Right Ventricular Diastolic Dysfunction

RVDD
Start date: July 20, 2020
Phase:
Study type: Observational

Heart-lung interactions remain misunderstood whereas pulmonary and cardiac pathologies are very commonly associated. Emphysema by increasing intrathoracic pressure appears to affect cardiac function. Interestingly, previous studies have shown a link between the telediastolic volume of the right ventricle (measured by RMI) and the intensity of emphysema. Our hypothesis is that the emphysema by increasing intrathoracic pressure leads to or accentuates right cardiac diastolic dysfunction by decreasing compliance and cardiac preload. To verify this hypothesis the investigators will perform KT loop procedures in order to acquire intracardiac pressure/volume curves before and after lung volume reduction. The pressure/volume curves allow the analysis of systolic and diastolic function, cardiac contractility and loading conditions.

NCT ID: NCT04466020 Completed - Cancer Clinical Trials

SELF - BREATHE for Chronic Breathlessness

Start date: June 3, 2020
Phase:
Study type: Observational

Semi-structured qualitative interviews will be conducted to understand key factors that would enable / facilitate patients with chronic breathlessness to potentially use an online breathlessness intervention (SELF-BREATHE).