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Clinical Trial Summary

Post-thrombotic syndrome (PTS) is the most frequently observed chronic complication of deep vein thrombosis (DVT), with an estimated cumulative incidence of 20-50%. Endovascular venous recanalization with angioplasty and stenting of obstructive lesions is the recommended treatment option to reduce or correct the symptoms of DVT. However, its impact on the physical capacity and breathlessness of patients has not been fully demonstrated. The heterogeneous evidences of clinical improvement is probably related to the presence or absence of collateral veins developed in these patients with proximal venous obstruction (iliac or iliofemoral with or without inferior vena cava involvement), which ensure the cardiac venous return. The aim of this study is to compare changes in maximal oxygen uptake after endovascular venous recanalization in DVT patients and to evaluate the hemodynamic, respiratory and muscular improvement induced by the restoration of venous flow in the occluded segments.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05794932
Study type Interventional
Source University Hospital, Montpellier
Contact Valérie MONNIN-BARES, MD
Phone +334 67 33 59 91
Email v-monnin@chu-montpellier.fr
Status Recruiting
Phase N/A
Start date April 17, 2023
Completion date December 17, 2025

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