View clinical trials related to Chronic Pain.
Filter by:This Phase 3, multi-center study will evaluate the long-term safety and tolerability of hydrocodone bitartrate controlled release capsule (HC-CR) at daily doses of 40 mg or more in subjects with moderate to severe chronic pain. Long-term maintenance of HC-CR efficacy will be evaluated.
The purpose of the study is to gather clinical information on subjects' experiences with and without the use of the new feature of the RestoreSensor implantable neurostimulator (INS).
The purpose of this study is to quantify the effect of multiple doses of PF-04531083 on the pharmacokinetics (PK) of co-administered single dose simvastatin.
We would like to determine how well hypnosis works when induced through virtual reality medium for patients who have suffered a major burn injury in the past two years and suffer from chronic pain. These patients are coming back to the outpatient burn and plastic clinic at Harborview Medical Center for routine follow-up. We think that patients will find VR-Hypnosis interesting, and it will help them relax and feel less pain.
Millions of individuals with chronic pain smoke and our preliminary research suggests that currently available strategies to help people quit smoking may not be effective for individuals with chronic pain. This is important in that smokers with chronic pain have worse pain-related health outcomes compared to nonsmokers with chronic pain. The primary aim of this research project is to develop a smoking cessation intervention for specific use in an outpatient clinical setting for smokers with chronic pain.
The purpose of this study is to determine if the combination of thoracic paravertebral block and multimodal analgesia will decrease chronic pain and arm morbidity in patients undergoing breast cancer surgery with lymph node dissection as compared to patients receiving local anesthesia with multimodal analgesia.
The purpose of this study is to determine the safety and efficacy of Deep Brian Stimulation (DBS) of the ventral capsular/ventral striatal as a treatment for patients with Thalamic Pain Syndrome (TPS). The central hypothesis to be tested in this investigation is that VC/VS stimulation will modulate the affective component of TPS and, consequently, improve pain related disability.
This randomised prospective study was designed to compare the convalescence and the long-term sequelae in inguinal hernia repair with either a bilayer mesh as devised by Gilbert (Prolene Hernia System®) or an onlay mesh applied according to Lichtenstein.
This is an explorative study investigating potential nerve injury after VATS.
Primary objective shared by the 3 registries : Describe the different pharmacotherapeutic management in patients : - DB (Diabetes): with type 2 diabetes, treated with oral and / or injectable antidiabetics - CP (Chronic Pain): with any disease leading to chronic pain (lasting for more than 3 months) - AF (Atrial Fibrillation): with ongoing AF or AF diagnosed within 12 months before enrollment Secondary objectives shared by the 3 observatories: - Describe the occurrence of clinical events, hospitalizations and death, according to the different medical care conditions, and analyze their predicting factors - Estimate the resources consumption according to the medical and non medical management of these patients, - Analyze the impact of some factors (patient's cognitive status, autonomy, renal function ...) on the current practice Secondary objectives specific shared by DB and AF registries : - Analyze the geriatric pharmaco-genetic aspects Specific secondary objectives for each observatory : - DB : Describe HbA1c level, percentage of responders and body weight evolution according to the different medical care conditions - CP : Evaluate pain consequences on Daily Living Activities and patient autonomy