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Cataract clinical trials

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NCT ID: NCT01127711 Completed - Clinical trials for Cardiovascular Diseases

Cohort of Swedish Men

COSM
Start date: September 1997
Phase: N/A
Study type: Observational

The Cohort of Swedish Men began in 1997, when all men born between 1918 and 1952 and residing in two counties in central Sweden received a questionnaire including about 350 items concerning diet and other lifestyle factors. A second questionnaire was sent out in 2008-09.

NCT ID: NCT01127698 Completed - Clinical trials for Cardiovascular Diseases

Swedish Mammography Cohort

SMC
Start date: March 1987
Phase: N/A
Study type: Observational

The Swedish Mammography Cohort began in 1987-1990, when 66,651 women living in two counties in central Sweden completed a mailed questionnaire that included items about their diet, parity, age at first child's birth, history of breast cancer in family, weight, height, and education. Follow-up questionnaires have been sent out in 1997 and in 2008-09.

NCT ID: NCT01124045 Completed - Inflammation Clinical Trials

Difluprednate Pediatric Study for the Treatment of Inflammation Post-Cataract Surgery

Start date: August 2010
Phase: Phase 3
Study type: Interventional

The primary objective of this study was to compare the safety and efficacy of Durezol™ compared to Pred Forte™ for the treatment of inflammation following cataract surgery in a pediatric population 0 to 3 years of age.

NCT ID: NCT01123928 Completed - Cataract Clinical Trials

Guangdong Uptake of Surgery Trial

GUSTO
Start date: July 2010
Phase: N/A
Study type: Interventional

The purpose of this study is: 1. To determine whether an educational intervention designed based on studies in the area is effective in increasing acceptance of surgery and presentation to the hospital, when adjusting for a number of potential determinants of service uptake; 2. To assess short-term impact of the educational intervention on knowledge about cataract and attitudes toward locally-available surgical services.

NCT ID: NCT01122576 Completed - Cataract Clinical Trials

Evaluation of 3 Intraocular Lenses Following Lens Extraction

Start date: June 2010
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate the efficacy and subject satisfaction with three different FDA approved lenses for adults over 40 years of age who desire a reduction in spectacle dependence.

NCT ID: NCT01109173 Completed - Cataract Clinical Trials

Confirmatory Study Nepafenac 0.3%

Start date: June 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study was to assess the safety and efficacy of an investigational eye drop intended for the prevention and treatment of inflammation (swelling and redness) and pain in the eye after cataract extraction.

NCT ID: NCT01103401 Completed - Cataract Clinical Trials

Ketorolac Plus Tobramycin/Dexamethasone Versus Tobramycin/Dexamethasone After Uneventful Phacoemulsification Surgery

Start date: October 2009
Phase: N/A
Study type: Interventional

This randomized controlled trial compares two regimens of topical therapy: - tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon), one drop four times/day - combination of tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon), one drop four times/day, plus Ketorolac tromethamine 0.5% (Acular®, Allergan), one drop three times/day. Patients are independently assessed by two ophthalmologists. On days 7,14,21,28 patients are evaluated for - corneal edema - conjunctival hyperemia - anterior chamber (Tyndall) reaction. The investigators purpose was to evaluate the benefit of adding a non-steroid agent to an antibiotic/steroid combination after uneventful phacoemulsification. Adopting a weekly follow-up, to gain insight into the optimal duration of postoperative treatment and to examine whether risk factors for inflammation exist.

NCT ID: NCT01098812 Completed - Cataract Clinical Trials

Clinical Evaluation of a 1-Piece Intraocular Lens

Start date: March 2010
Phase: Phase 3
Study type: Interventional

The aims of this study are to: - Demonstrate a reduction in postoperative cylinder compared to results from the control lens - Demonstrate better uncorrected distance visual acuity compared to the control lens

NCT ID: NCT01085357 Completed - Cataract Clinical Trials

Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery

COMPASS
Start date: September 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the CyPass Implant for lowering intraocular pressure (IOP) in patients with glaucoma who undergo cataract surgery.

NCT ID: NCT01078103 Completed - Diabetes Clinical Trials

Corneal Endothelial Changes Associated With Phacoemulsification in Diabetes Mellitus Type II

Start date: July 2005
Phase: Phase 4
Study type: Observational

Some studies indicated that the diabetic corneal endothelium is morphologically abnormal and may be at risk in any intraocular surgical procedure, while others showed no significant differences between diabetic and non-diabetic corneal endothelium.The purpose of this study is to investigate the differences in corneal endothelial cell density and morphology in diabetic patients and normal patients after phacoemulsification with intraocular lens implantation.To investigate if haemoglobin A1c can be used as a predictor of corneal endothelial cell changes after phacoemulsification.