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Cataract clinical trials

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NCT ID: NCT01076309 Completed - Cataract Clinical Trials

Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Tamsulosin

Start date: June 2009
Phase: N/A
Study type: Observational

The purpose of this study is to determine whether corneal endothelium cell loss during cataract surgery is higher in patients taking Tamsulosin.

NCT ID: NCT01069341 Completed - Clinical trials for Proliferative Diabetic Retinopathy

Use of Ranibizumab to Treat Rubeosis in Diabetics Prior to Cataract Surgery

Start date: July 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study was to determine the safety of ranibizumab: a) as a surgical adjunct during cataract surgery in subjects with proliferative diabetic retinopathy (PDR) induced rubeosis and, b) in treatment of proliferative diabetic retinopathy (PDR).

NCT ID: NCT01069172 Completed - Cataract Clinical Trials

Study of the Femtosecond Laser System as Compared to Continuous Curvilinear Capsulorhexis for Cataract Surgery

Start date: February 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the OptiMedica Femtosecond Laser System to perform surgical maneuvers used in the treatment of subjects with cataracts. The safety and efficacy will be compared to the standard surgical procedure of continuous curvilinear capsulorhexis (CCC) and ultrasonic phacoemulsification.

NCT ID: NCT01069029 Completed - Visual Acuity Clinical Trials

Combined Versus Successive Macular Hole and Cataract Surgery

Start date: January 2006
Phase: N/A
Study type: Observational

The purpose of this study is to compare functional and anatomical results of a combined surgery and two time surgery for macular hole and cataract extraction in one hundred and twenty patients (120 eyes) with idiopathic Macular Hole (MH) and cataract in two academic centers.

NCT ID: NCT01061918 Completed - Cataract Clinical Trials

Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses

Start date: August 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR intraocular lenses (IOLs) 6 months post cataract surgery.

NCT ID: NCT01061463 Completed - Cataracts Clinical Trials

Occupational Cataracts and Lens Opacities in Interventional Cardiology : the O'CLOC Study

Start date: October 2009
Phase: N/A
Study type: Observational

The purpose of this study is to test the existence of an increased risk of cataracts among interventional cardiologists as compared to cardiologists not exposed to X-rays.

NCT ID: NCT01052558 Completed - Glaucoma Clinical Trials

GTS400 Stent Implantation in Conjunction With Cataract Surgery in Subjects With Open-angle Glaucoma

Start date: January 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the GTS400 trabecular micro-bypass stent in reducing intraocular pressure (IOP) in subjects with open-angle glaucoma or ocular hypertension and co-existing cataract.

NCT ID: NCT01051648 Completed - Cataract Clinical Trials

Triamcinolone Assisted Anterior Vitrectomy

Start date: December 2007
Phase: Phase 2
Study type: Interventional

Injecting Triamcinolone acetenoide for visualizing and removing vitreous from the anterior chamber.

NCT ID: NCT01045733 Completed - Cataract Clinical Trials

A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)

Start date: December 2009
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate and compare postoperative corneal aberrations and visual parameters in patients contralaterally implanted with an AcrySof IQ Toric intraocular lens (IOL) and AcrySof IQ Aspheric IOL with concomitant limbal relaxing incision.

NCT ID: NCT01030601 Completed - Diabetes Clinical Trials

Analysis of the Effect of Intravitreal Dexamethasone Injection on Diabetic Macular Edema After Cataract Surgery (IDDMECS)

IDDMECS
Start date: January 2010
Phase: Phase 2
Study type: Interventional

Macular Edema (Swelling of a particular site of the retina) can become a significant problem for Diabetics undergoing Cataract surgery. And a significant number of people who undergo Cataract surgery each year are diabetics. And when you multiply these two factors together you are left with a significant number of people who do not gain as much vision as their peers. Diabetics who develop Macular Edema actually can loose some vision after surgery and when you follow them up, they don't gain as much vision. This Study aims to prevent such an event from happening and therefore allow Diabetics to gain as much vision as they can from cataract surgery. This study will use Dexamethasone injected intravitreally (into the gel of the eye) at the end of cataract extraction to control Macular edema brought about by surgery. The main outcome is the central retina thickness and retinal volume as measured by Optical Coherence Tomography. Secondary outcomes are BCVA and incidence of Laser Treatment. Other Drugs, life Bevacizumab and Pegaptanib, have been used for this purpose but they are expensive and have potential systemic side-effects due to anti-VEGF (vascular endothelial growth factor) actions. Dexamethasone has been used in the eye for decades and is short-lived, minimizing possible systemic effects. Moreover, this drug is at least 15x cheaper than the previously mentioned ones and therefore has tremendous benefit for developing countries. We seek an alternative drug that can reduce or prevent Macular edema at a less expensive and safer way.