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NCT06253962 Clinical Trial

Carotid Atherosclerosis in Predicting Coronary Artery Disease

Carotid Atherosclerosis Clinical Trial

— CACA  

Official title:
Carotid Atherosclerosis in Predicting Coronary Artery Disease

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06253962
Other study ID # CACA
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date February 10, 2024
Est. completion date December 31, 2028

Study information
Verified date February 2024
Source Shanghai Zhongshan Hospital
Contact Danbo Lu, PhD
Phone +86 021 64041990
Email lu.danbo@zs-hospital.sh.cn
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Carotid plaque burden and composition features, particularly lipid necrotic core, are significantly associated with severity of CAD stenosis. This study aims to explore the relationship between various phenotypic patterns of carotid atherosclerosis with the prevalence, phenotype, and severity of coronary atherosclerosis. The patients with chest tightness or chest pain will receive carotid artery ultrasonography before coronary angiography so as to explore the relationship between them.

Recruitment information / eligibility
Status Recruiting
Enrollment 1000
Est. completion date December 31, 2028
Est. primary completion date December 31, 2026
Accepts healthy volunteers No
Gender All
Age group 14 Years to 90 Years
Eligibility Inclusion Criteria: - patients receive carotid ultrasound and coronary angiography Exclusion Criteria: - None

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• coronary agiongraphy
severity of coronary atherosclerosis

Locations
Country Name City State
China 180 Fenglin Road Shanghai

Sponsors (1)
Lead Sponsor Collaborator
Shanghai Zhongshan Hospital

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary MACE acute myocardial infarction; heart failure; cardiac death; revascularization two years after angiography
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