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Carotid Artery Stenosis clinical trials

View clinical trials related to Carotid Artery Stenosis.

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NCT ID: NCT03764306 Terminated - Stroke, Ischemic Clinical Trials

New Ischemic Cerebral Lesions After Endarterectomy vs. Stenting for the Treatment of Symptomatic Carotid Stenosis

CARECarotid
Start date: May 1, 2015
Phase: N/A
Study type: Interventional

Background and purpose. Even if periprocedural cerebral microembolism associated with carotid endarterectomy or stenting usually does not manifest as clinically overt stroke, neuropsychological disturbances resulting from these events represent an important clinical and socioeconomic problem. Still, it remains unclear whether the use proximal protection can lower the incidence of cerebral embolism associated with the treatment of carotid stenosis. Materials and methods. This was a prospective randomised single-centre study, which was aimed at comparison of surgical eversion endarterectomy with stenting under proximal protection in symptomatic patients. The investigators evaluated the incidence of new ischaemic lesions revealed by the diffusion-weighted magnetic resonance imaging 2-4 days after the treatment and neurologic events.

NCT ID: NCT03464851 Terminated - Clinical trials for Carotid Artery Stenosis

Evaluation of a Novel Technique to Diagnose Carotid Artery Stenosis

Start date: March 8, 2018
Phase:
Study type: Observational

The purpose of this study is to determine the accuracy of a new non-invasive device, the Carotid Stenotic Scan (CSS), to check for stenosis of the internal carotid artery (ICA) as compared to a carotid ultrasound study.

NCT ID: NCT01236508 Terminated - Stroke Clinical Trials

Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease

Start date: November 2010
Phase: Phase 4
Study type: Interventional

The investigators hypothesize that inflammation in carotid plaque is predictive of the extent of ischemic lesion burden on the brain and will add to risk stratification for individuals with carotid disease.

NCT ID: NCT00805311 Terminated - Stroke Clinical Trials

Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis

AMTEC
Start date: April 2009
Phase: Phase 4
Study type: Interventional

The aim of this study is to determine whether optimal medical treatment can postpone carotid endarterectomy.

NCT ID: NCT00597545 Terminated - Diabetes Clinical Trials

Effect of Raised CBF During CEA on Cognition in DM Patients

Start date: March 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if we can reduce the incidence of cognitive dysfunction — difficulty in performing certain pencil-paper, memory, finger dexterity and thinking type of tasks called neuropsychometric tests — in patients with adult onset diabetes mellitus (DM) undergoing surgery on the carotid artery (CEA). We hypothesize that cognitive dysfunction can be decreased in patients with type II DM by augmenting cerebral blood flow with a shunt during carotid endarterectomy compared to patients with Type II DM who are treated with "conventional" management in which a shunt is placed only if the electroencephalogram (EEG) indicates cerebral ischemia.

NCT ID: NCT00335972 Terminated - Clinical trials for Carotid Artery Stenosis

The Effects of Dexmedetomidine and Remifentanil on Carotid Patients

Start date: June 2006
Phase: Phase 4
Study type: Interventional

We propose to test whether intraoperative administration of dexmedetomidine will reduce hemodynamic control in the intra- and post-operative periods and reduces PACU analgesic requirements in patients undergoing carotid endarterectomy.